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Annotation:
Pathological anatomy is part of basic study subjects. It introduces students to the nature of human diseases, the cause of diseases (etiology), the mechanisms of their development (pathogenesis) and the changes in cells and tissues caused by the disease (morphology of diseases).
General pathology:
Cell injury, death and adaptation; inflammation and repair; disorders of vascular flow; disorders of the immune system; genetic and pediatric diseases; environmental diseases; infectious diseases; neoplasia.
Entry requirements:
Biology II, Physiology II
Poslední úprava: Žáková Michaela, Bc. (11.09.2025)
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Compulsory literature: 1. Kumar V, Abbas AK, Aster JC: Robbins Basic Pathology. 9. vyd., Elsevier, 2013. ISBN 978-1437717815 2. Zámečník J. et al.: Patologie. Praha, LD, s.r.o. - Prager Publishing, 2024 - 2. vydání. ISBN 978-80-11-04919-5 Poslední úprava: Žáková Michaela, Bc. (11.09.2025)
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Conditions for granting pathology credit in winter term: Credit examination takes place on the last two pathology practical classes, in the period from 5 to 16 January 2026. The basic condition for granting the credit is participation in practical classes (one absence is accepted; each absence must be announced before the beginning of the class by e-mail to the teacher) and passing all e-tests during the practicals. More than one absence must be replaced in a way agreed with the assistant teacher. Credit is tested by a written test and subsequent oral examination. The test has 50 questions, the threshold is 80 % correct answers. Oral part is based in the diagnosis of one to two microscopic slides and verification of knowledge of the relevant theory. ≥ 80 % → oral examination → credit < 80 % → credit not awarded → 2nd attempt - oral examinatory → credit In the case of on-line teaching only, the credit will be tested solely by a written test with 50 questions. The minimum to meet is 80 % correct answers. For credit there are one regular and 2 additional terms. The last attempt is always tested only orally (slides and relevant theory). The credit is tested generally by the assistant professor of the group. Poslední úprava: Žáková Michaela, Bc. (11.09.2025)
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Sylabus: Lectures Lecturers: • Kateřina Kamarádová, MD, PhD • Petra Kašparová, MD, PhD • Adéla Matějková, MD, PhD • Tomáš Rozkoš, MD, PhD • Prof. Aleš Ryška, MD, PhD • Jiří Soukup, MD, PhD • Václav Stejskal, MD, PhD
1. Introductory lesson (prof. Ryška, 3 hours) - online 2. Cell injury, death and adaptation (prof. Ryška, 6 hours) - online 3. Inflammation and repair (dr. Kašparová, 6 hours) 4. Disorders of the immune system (dr. Kašparová, 6 hours) 5. Infectious diseases (dr. Rozkoš, 6 hours) 6. Neoplasia (prof. Ryška, 9 hours) 7. Environmental diseases (dr. Kamarádová, 6 hours) - online 8. Disorders of vascular flow (dr. Matějková, 6 hours) 9. Genetic and pediatric diseases (dr. Soukup, 6 hours) 10. Cardiovascular system (dr. Stejskal, 9 hours)
Practical courses & seminars Lecturers: • Group 7 (Friday, 1 - 3 h.) - dr. Podhola • Group 8 (Monday 1 - 3 h.) - dr. Stejskal • Group 9 (Tuesday 1 - 3 h.) - dr. Rozkoš
Practical courses: Regressive changes. Necrosis. Kidney infarction (č. 1); Myocardial infarction (č. 2); Pancreatic necrosis (acute pancreatitis) (č. 3); Brain malacia (č. 4); Hemorrhagic pulmonary infarction (č. 5); Tuberculosis of the adrenal gland (č. 6). Dystrophy. Hepatic steatosis (č. 10); Gaucher disease (spleen) (č. 11); Pigmented naevus intradermal (č. 12); Anthracosis and silicosis of the lung (č. 13); Hepatic hemochromatosis (č. 14); Hepatic hemochromatosis (Fe) (č. S14); Metastatic calcification in the lung (č. 13); Metastatic calcification in the lung (Kossa) (č. S13). Adaptation. Reparation. Lipomatous atrophy of the pancreas (č. 20); Muscle atrophy (č. 21); Myocardial hypertrophy (č. 22); Endometrial hyperplasia (č. 23); Myoadenomatous prostatic hyperplasia (č. 24); Cervical epithelial metaplasia + cystosis (č. 25); Wound healing (granulation tissue) (č. 26); Scar after myocardial infarction (č. 27); Scar after myocardial infarction (trichrom)(S27). Non-specific inflammation. Cytomegaly (adnate – lungs or liver) (č. 30); Herpetic esophagitis (č. V1); Fibrous pericarditis (č. 31); Abscessing parotitis (č. 32); Hematogenous kidney abscesses (č. 33); Acute pyelonephritis (č 34); Chronic cholecystitis (č. 35). Specific inflammations. Fungal and parasitic diseases. Tuberculosis of the lung (č. 40); Tuberculosis of the lung (BK) (č. S40); Pulmonary sarcoidosis (č. 41); Actinomycosis (č. 42); Foreign body granuloma (č. 43); Aspergillosis (pneumonia) (č. 44); Aspergillosis (pneumonia) (Groccott) (č. S44); Oxyuriasis of the appendix (č. 45). Circulatory disorders. Brain hemorrhage (č. 50); Posthemorrhagic pseudocyst (č. 51); Posthemorrhagic pseudocyst (Fe) (č. S51); Thrombosis of the calf veins (č. 52); Successive pulmonary embolism (č. 53); Successive pulmonary embolism (elastic - recanalization) (č. S53); Venostatic lung induration (č. 54); Venostatic lung induration (Fe) (č. S54); Pulmonary fat embolism (č. 55); Pulmonary fat embolism (sudan) (č. S55); Pulmonary edema (č. 56). Circulatory disorders. Immunopathology. Chronic venous congestion in the liver (č. 60); DIC kidney (č. 61); Amyloidosis of the kidney (č. 62); Amyloidosis of the kidney (Maldyk) (č. S62); Hashimoto's thyroiditis (č. 63); Toxic Goiter (Graves-Basedow) (č. 64); Acute rejection of a transplanted kidney (č. 65). Pseudotumours. Precancerous lesions. Polycystic kidney disease - adult type (č. 70); Epidermoid cyst of the skin (č. 71); Endometriosis (č. 72); M. Bowen (č. 73); Cervical dysplasia (CIN III/HSIL) (č. 74). Tumours. Dermatofibroma (č. 80); Uterine leiomyoma (č. 81); Capillary haemangioma (č. 82); Cavernous haemangioma (č. 83); Lipom (č. 84); Liposarcoma (č. 85); Osteosarcoma (č. 86). Epithelial tumors, mixed. Metastasis. Tubulovillous adenoma of the colon (č. 90); Condyloma acuminatum (č. 91); Pleomorphic adenoma of the parotid gland (č. 92); Colon cancer (č. 93); Metastasis of adenocarcinoma in the liver (č. 94); Carcinomatous lymphangioedema of the lung (č. 95); Melanoma metastasis in the lymph node (č. 96); Melanoma metastasis in the lymph node (SOX10) (č. S96) Credit examination (compulsory). Poslední úprava: Žáková Michaela, Bc. (15.09.2025)
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