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Annotation:
Pathological anatomy is part of basic study subjects. It introduces students to the nature of human diseases, the cause of diseases (etiology), the mechanisms of their development (pathogenesis) and the changes in cells and tissues caused by the disease (morphology of diseases).
Pathology of the male reproductive system; pathology of the female reproductive system; pathology of the nervous system; pathology of the skin; pathology of the musculoskeletal system; pathology of the endocrine system; pathology of the breast; developmental defects of the orofacial region; dental caries; pulp and periodontal diseases; pathology of the lips, tongue and oral mucosa; pseudotumors and cysts; odontogenic tumors; diseases of the jaws and maxillary sinus; non-neoplastic diseases of the salivary glands; salivary gland tumors; systemic diseases and syndromes with manifestations in the orofacial region; cervical lymphadenopathy.
Entry requirements:
Histology and Embryology II, Pathological Anatomy I
The aim of the course:
The subject of Pathological Anatomy II includes a part of special (organ) pathology and the whole of orofacial pathology. The aim of special pathology is to familiarize students with the etiopathogenesis, morphology, clinical manifestations and complications of the most important diseases of the male reproductive system, female reproductive system, nervous system, musculoskeletal system, endocrine system, breast, and skin. The aim of orofacial pathology is to familiarize students with the etiopathogenesis, morphology, clinical manifestations and complications of developmental defects of the head and neck area, dental caries and periodontal diseases, non-neoplastic diseases and benign and malignant tumors of the oral cavity, jaws, salivary glands and cervical lymph nodes and with the manifestations of systemic diseases in the head and neck area.
Poslední úprava: Žáková Michaela, Bc. (03.09.2026)
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Compulsory literature: 1. Zámečník J. et al.: Patologie. Praha, LD, s.r.o. - Prager Publishing, 2019. ISBN 978-80-270-6457-1 2. Kumar v, Abbas AK, Aster JC: Robbins Basic Pathology. 9. vyd. Elsevier, 2013. ISBN 978-1437717815. 3. Odell, E.W.: Cawson´s Essentials of Oral Pathology and Oral Medicine. 9th ed., Elsevier, 2017. ISBN 978-0-7020-4982-8
Recommended literature: 1. Slezák R, Dřízhal I: Atlas chorob ústní sliznice. Praha, Quintessenz, 2004. ISBN 80-903181-5-0
Poslední úprava: Žáková Michaela, Bc. (03.09.2026)
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Conditions for granting pathology credit and for examination in winter term: Credit Credit examination takes place on the last two pathology practical classes, in the period from 7 to 21 January 2027. The basic condition for granting the credit is participation in practical classes (one absence is accepted; each absence must be announced before the beginning of the class by e-mail to the teacher). More than one absence must be replaced in a way agreed with the assistant teacher. Another condition for awarding credit is passing all e-tests during practical classes. The e-test has 10 questions, the minimum for passing is 80 % correct answers. The oral part of credit consists of diagnostics of two microscopic slides and verifying knowledge of the relevant theory. A student who does not achieve 80 % success in e-tests or has more than one absence will be given five microscopic slides for diagnostics and the relevant theory for the oral part of the credit. For credit there are one regular and 2 additional terms. The credit is tested generally by the assistant professor of the group.
Exam Exam period 25. 1. – 19. 2. 2027. The exam is oral and includes a total of 3 questions, namely 1x general pathology, 1x special pathology and 1x orofacial pathology. The student can take the exam only after obtaining credit for both semesters (must be registered in SIS). The student registers for the exam via SIS. Students will receive information about the exam dates and detailed instructions during the lecture and will be published in SIS no later than a month before the start of the exam period.
Repeating the course: When repeating the course Pathological Anatomy: Pathological anatomy I (summer term) - recommended. Pathological anatomy II (winter term) - it is mandatory to complete the entire winter semester course. Poslední úprava: Žáková Michaela, Bc. (03.09.2026)
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Lectures Lecturers: • Aleš Kohout, MD, Ph.D. • Kateřina Kamarádová, MD, PhD • Prof. MUDr. Jan Laco, Ph.D. • MUDr. Miroslav Podhola, Ph.D. • Prof. MUDr. Aleš Ryška, Ph.D.
Systemic Pathology (continued) 1. Female genital system (prof. Laco, 3 hod.) 2. Musculoskeletal system. (prof. Laco, 3 hod.) 3. Male genital system. (prof. Laco, 3 hod.) 4. Endocrine system. Breast. (prof. Ryška, 3 hod.) 5. Nervous system. Skin. (dr. Kohout, 3 hod.)
Oral Pathology 6. Developmental disorders (prof. Laco, 3 hod.) 7. Systemic disorders and syndromes with head and neck region manifestation. (dr. Kamarádová, 3 hod.) 8. Pathology of lips, tongue and oral mucosa I. (dr. Kamarádová, 3 hod.) 9. Pathology of lips, tongue and oral mucosa II. (dr. Kamarádová, 3 hod.) 10. Caries. Pulpal and periodontal disorders. (prof. Laco, 3 hod.) 11. Pseudotumors and cysts. (prof. Laco, 3 hod.) 12. Odontogenic tumors. (prof. Laco, 3 hod.) 13. Diseases of jaws and maxillary sinus. (prof. Laco, 3 hod.) 14. Nonneoplastic salivary gland disorders. (prof. Laco, 3 hod.) 15. Salivary gland tumors. (prof. Laco, 3 hod.)
Practical Classes: Lecturers Michaela Kopalová, MD Tereza Sokolová, MD
Practical Classes 1. Introduction: Parotid gland (124). Submandibular gland (125). Sublingual gland (126). Tooth development (179a). 2. Inflammations and Reactive Lesions of Salivary Glands: Acute purulent sialadenitis (131). Chronic sialadenitis (132). Interstitial sialadenitis (mumps) (130). Cytomegalovirus sialadenitis (144). Lymphoepithelial sialadenitis (Sjögren syndrome)(208). Necrotizing sialometaplasia (133a). 3. Tumors od Salivary Glands: Pleomorphic adenoma (184). Warthin tumor (186). Adenoid cystic carcinoma (185). Mucoepidermoid carcinoma (187). Acinic cell carcinoma (220). Salivary duct carcinoma (187a). 4. Inflammations: Herpetic esophagitis (145). Candida glossitis (128+Gram). Lichen planus (206). Pemphigus vulgaris (221). Pemphigoid (222). 5. Inflammations: Acute osteomyelitis (223). Chronic sinusitis (134). Hypersensitive sinusitis (135). Granulomatous cheilitis (143). Actinomycosis (142). 6. Cysts: Radicular cyst (136a, 136b, 136c). Lymphoepithelial cyst (137). Epidermoid cyst (138). Thyreoglossal duct cyst (139). Mucocele (178). 7. Reactive Lesions and Benign Tumors: Giant cell epulis (168). Congenital granular cell epulis (226). Squamous cell papilloma (224). Fibroma (171). Hemangioma (175). Lymphangioma (225). Lipoma (181). Granular cell tumor (183). Schwannoma (227). 8. Precancerous Lesions and Malignant Tumors; Melanocytic Lesions: Leukoplakia (167). Actinic cheilitis (228). Squamous cell carcinoma (198). Basalioma (197). Pigmented nevus (194). Malignant melanoma (195). 9. Non-neoplastic Lesions of Jaws: Cherubism (177c). Central giant cell granuloma (229). Fibrous dysplasia (230). Paget disease of bone (210). Osteoma (177). 10. Odontogenous Tumors of Jaws: Ameloblastoma (179). Pindborg tumor (211). Keratocystic odontogenous tumor (231). Ameloblastic fibroma (211b). Odontoma (232). 11. Non-odontogenous Tumors of Jaws: Osteochondroma (233). Osteosarcoma (177b). Chondroma (201a). Chondrosarcoma (201b2). Langerhans cell histiocytosis (235). 12. Lesions of Lymphatic Nodes and Thyroid Gland: Sarcoidosis (163). Tuberculosis (165). Toxoplasmosis (166a). Graves disease (160). Follicular adenoma (236). Papillary carcinoma (237). 13. Revision seminar. 14. Credit. Poslední úprava: Žáková Michaela, Bc. (03.09.2026)
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