Pharmacology, pharmacodynamics, molecular mechanisms of drug action and drug
targets, pharmacokinetics, monitoring drug plasma concentration in relation to therapeutic
effects, adverse effects of drugs, system and disease oriented drug groups with
pharmacological profiles.
Poslední úprava: Kolářová Jana (08.03.2021)
Cíl předmětu - angličtina
Knowledge and skills to be acquired: prescription, general knowledge of the basic principles of pharmacology - pharmacokinetics, pharmacodynamics. Special knowledge of basic principles of pharmacology - knowledge of the groups of drugs according to anatomical systems and their diseases, including clinical indications and adverse effects.
Poslední úprava: MAT89030 (15.10.2012)
Literatura
Povinná:
Katzung, Bertram G. Kruidering-Hall, Marieke Tuan, Rupa Lalchandani Vanderah, Todd W. Trevor, Anthony J.. Katzung & Trevor's pharmacology : examination & board review. New York: McGraw-Hill, 2021, 600 s. ISBN 978-1-260-11712-7.
Ritter, James Flower, R. J. Henderson, Graeme Loke, Yoon Kong MacEwan, David J. Robinson, Emma S. J., Fullerton, James. Rang & Dale's pharmacology. London: Elsevier, 2024, 850 s. ISBN 978-0-323-87395-6.
Brunton, Laurence L. Knollmann, Björn C. (eds.). Goodman & Gilman's the pharmacological basis of therapeutics. New York: McGraw Hill, 2023, 1645 s. ISBN 978-1-264-25807-9.
Doporučená:
Karen Whalen. Lippincott® Illustrated Reviews: Pharmacology, 8th Edition. Philadelphia, US: Lippincott Williams & Wilkins, 2021, 704 s. ISBN 9781975170554.
Lüllmann, Heinz, Mohr, Klaus, Hein, Lutz. Color atlas of pharmacology. Stuttgart ; New York: Thieme, 2018, 444 s. ISBN 978-3-13-241065-7.
Poslední úprava: Canová Nikolina, MUDr., Ph.D. (13.09.2024)
Metody výuky - angličtina
Pharmacology 2 B80386
Organization of teaching the master's form of General medicine + Erasmus study at the Institute of Pharmacology of the 1st Medical Faculty of Charles University for the winter semester 2026/2027:
Teaching takes place in the form of lectures and seminars according to the schedule published in the SIS.Attendance at lectures is recommended, attendance at seminars is mandatory.
An exceptions are the first three teaching weeks of the semester, when presence lectures take place (seminars do not take place). Plese, follow "Schedule" in the SIS.
Schedule of group seminars, teachers, and lecture rooms in the Institute of Pharmacology, 1st Faculty of Medicine, Charles University in Prague, Albertov 4, Prague 2:
Thursdays 13.00 - 14.30 - Lectures in the lecture hall of the Institute of Pharmacology (since 01.10. 2026 )
If you have any questions, do not hesitate to contact us.
PharmDr. Alena Pilková (alena.pilkova@vfn.cz), representative for teaching
prof. MUDr. Ondřej Slanař, Ph.D. (oslan@lf1.cuni.cz ), head of the department
Poslední úprava: Šafářová Lenka (06.10.2026)
Sylabus - angličtina
Topics of lectures and seminars:
• Antihypertensives, pharmacotherapy of hypertension
• Antiobesity drugs
• Medicines that affect blood clotting
• Hypolipidemics
• Antiarrhythmics
• Antivirals
• Antibiotics
• Antidiabetics, insulins
• Pharmacotherapy of thyroid disorders
• Treatment of osteoporosis
• Immunopharmacology
• Cell and gene therapy, biological treatment
• Anticancer pharmacotherapy
• Remedies for respiratory diseases
• Pharmacotherapy of acute conditions
• Pharmacotherapy of pregnant women, lactating women, children and the elderly
• Drugs for diseases of the urogenital tract, drugs used in obstetrics
Poslední úprava: Kolářová Jana (08.03.2021)
Rozpis výuky -
Rozpis stáž
Týden bloku
Obsah stáže
Soubory
Poznámka
Hodnocení
4
Pharmacotherapy of bacterial diseases - case reports.
Pharmacology seminars
5
Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
Pharmacology seminars
6
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
Pharmacology seminars
7
TDM (therapeutic drug monitoring) - separate schedule.
Pharmacology seminars
8
Hypertension therapy overview + case reports
Pharmacology seminars
9
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction
Pharmacology seminars
10
Pharmacotherapy of respiratory tract system diseases - case reports.
Pharmacology seminars
11
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
Pharmacology seminars
12
Pharmacotherapy in rheumatology: rheumatoid arthritis, osteoarthritis, gout.
Pharmacology seminars
13
Repetition of psychotropic drugs.
Pharmacology seminars
14
Test - psychotropic drugs. Repetition of prescription writing.
Pharmacology seminars
15
Pharmacotherapy of acute conditions – case studies. CREDIT
Pharmacology seminars
Rozpis semestrální
Výukový týden
Datum
Od - Do
Typ výuky
Téma
Učitel
Soubory
Poznámka
Hodnocení
1
01.10.2026
13:00 - 14:30
přednáška
Pharmacotherapy of ischemic heart disease. Overview of antiarrhythmic drugs.
MUDr. Nikolina Canová, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4,
2
08.10.2026
13:00 - 14:30
přednáška
Heart failure. Diuretics. Therapy of hypertension.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4,
3
15.10.2026
13:00 - 14:30
přednáška
Antimicrobials
PharmDr. Sara Merdita
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
4
22.10.2026
13:00 - 14:30
přednáška
Antivirals, antifungals, antiparasitics.
PharmDr. Sara Merdita
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
5
29.10.2026
13:00 - 14:30
přednáška
Anticoagulants and anti-platelet drugs; fibrinolytics and antifibrinolytics.
PharmDr. Sara Merdita
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
6
05.11.2026
13:00 - 14:30
přednáška
Hypolipidemics. An overview of the possibilities of pharmacological influence of the metabolic syndrome.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
7
12.11.2026
13:00 - 14:30
přednáška
Overview of hypothalamic-pituitary hormones. Corticosteroids.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
8
19.11.2026
13:00 - 14:30
přednáška
Drugs used in diseases of the respiratory system.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
9
26.11.2026
13:00 - 14:30
přednáška
Drugs used in diseases of gastrointestinal tract.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
10
03.12.2026
13:00 - 14:30
přednáška
Cell and gene therapy, biological treatment. Immunopharmacology.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
12
17.12.2026
13:00 - 14:30
přednáška
Drugs used to treat diseases of the urogenital tract, drugs used in obstetrics.
MUDr. Olga Bartošová, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
13
07.01.2027
13:00 - 14:30
přednáška
Pharmacotherapy in pregnant women, breastfeeding, children and the elderly.
MUDr. Karolína Hronová, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
14
14.01.2027
13:00 - 14:30
přednáška
Drugs in palliative therapy
MUDr. Olga Bartošová, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
15
21.01.2027
13:00 - 14:30
přednáška
Acute and chronic drug intoxication – treatment and antidotes.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
Schedule study visit
Week of the block
Summary of the study visit
Files
Note
Hodnocení
4
Pharmacotherapy of bacterial diseases - case reports.
Pharmacology seminars
5
Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
Pharmacology seminars
6
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
Pharmacology seminars
7
TDM (therapeutic drug monitoring) - separate schedule.
Pharmacology seminars
8
Hypertension therapy overview + case reports
Pharmacology seminars
9
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction
Pharmacology seminars
10
Pharmacotherapy of respiratory tract system diseases - case reports.
Pharmacology seminars
11
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
Pharmacology seminars
12
Pharmacotherapy in rheumatology: rheumatoid arthritis, osteoarthritis, gout.
Pharmacology seminars
13
Repetition of psychotropic drugs.
Pharmacology seminars
14
Test - psychotropic drugs. Repetition of prescription writing.
Pharmacology seminars
15
Pharmacotherapy of acute conditions – case studies. CREDIT
Pharmacology seminars
Schedule semestral
Educational week
Date
From - To
Education type
Theme
Teacher
Files
Note
Hodnocení
1
01.10.2026
13:00 - 14:30
lecture
Pharmacotherapy of ischemic heart disease. Overview of antiarrhythmic drugs.
MUDr. Nikolina Canová, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4,
2
08.10.2026
13:00 - 14:30
lecture
Heart failure. Diuretics. Therapy of hypertension.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4,
3
15.10.2026
13:00 - 14:30
lecture
Antimicrobials
PharmDr. Sara Merdita
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
4
22.10.2026
13:00 - 14:30
lecture
Antivirals, antifungals, antiparasitics.
PharmDr. Sara Merdita
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
5
29.10.2026
13:00 - 14:30
lecture
Anticoagulants and anti-platelet drugs; fibrinolytics and antifibrinolytics.
PharmDr. Sara Merdita
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
6
05.11.2026
13:00 - 14:30
lecture
Hypolipidemics. An overview of the possibilities of pharmacological influence of the metabolic syndrome.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
7
12.11.2026
13:00 - 14:30
lecture
Overview of hypothalamic-pituitary hormones. Corticosteroids.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
8
19.11.2026
13:00 - 14:30
lecture
Drugs used in diseases of the respiratory system.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
9
26.11.2026
13:00 - 14:30
lecture
Drugs used in diseases of gastrointestinal tract.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4
10
03.12.2026
13:00 - 14:30
lecture
Cell and gene therapy, biological treatment. Immunopharmacology.
prof. MUDr. Ondřej Slanař, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4