Pharmacology, pharmacodynamics, molecular mechanisms of drug action and drug
targets, pharmacokinetics, monitoring drug plasma concentration in relation to therapeutic
effects, adverse effects of drugs, system and disease oriented drug groups with
pharmacological profiles.
Poslední úprava: Kolářová Jana (08.03.2021)
Cíl předmětu - angličtina
Knowledge and skills to be acquired: prescription, general knowledge of the basic principles of pharmacology - pharmacokinetics, pharmacodynamics. Special knowledge of basic principles of pharmacology - knowledge of the groups of drugs according to anatomical systems and their diseases, including clinical indications and adverse effects.
Poslední úprava: MAT89030 (15.10.2012)
Literatura
Povinná:
Katzung, Bertram G. Kruidering-Hall, Marieke Tuan, Rupa Lalchandani Vanderah, Todd W. Trevor, Anthony J.. Katzung & Trevor's pharmacology : examination & board review. New York: McGraw-Hill, 2021, 600 s. ISBN 978-1-260-11712-7.
Ritter, James Flower, R. J. Henderson, Graeme Loke, Yoon Kong MacEwan, David J. Robinson, Emma S. J., Fullerton, James. Rang & Dale's pharmacology. London: Elsevier, 2024, 850 s. ISBN 978-0-323-87395-6.
Brunton, Laurence L. Knollmann, Björn C. (eds.). Goodman & Gilman's the pharmacological basis of therapeutics. New York: McGraw Hill, 2023, 1645 s. ISBN 978-1-264-25807-9.
Doporučená:
Karen Whalen. Lippincott® Illustrated Reviews: Pharmacology, 8th Edition. Philadelphia, US: Lippincott Williams & Wilkins, 2021, 704 s. ISBN 9781975170554.
Lüllmann, Heinz, Mohr, Klaus, Hein, Lutz. Color atlas of pharmacology. Stuttgart ; New York: Thieme, 2018, 444 s. ISBN 978-3-13-241065-7.
Poslední úprava: Canová Nikolina, MUDr., Ph.D. (13.09.2024)
Metody výuky - angličtina
Pharmacology 2 B80386
Organization of teaching the master's form of General medicine + Erasmus study at the Institute of Pharmacology of the 1st Medical Faculty of Charles University for the winter semester 2025/2026:
Teaching takes place in the form of lectures and seminars according to the schedule published in the SIS.Attendance at lectures is recommended, attendance at seminars is mandatory.
An exceptions are the first three teaching weeks of the semester, when compulsory presence lectures take place (seminars do not take place). Plese, follow "Schedule" in the SIS.
Schedule of group seminars, teachers, and lecture rooms in the Institute of Pharmacology, 1st Faculty of Medicine, Charles University in Prague, Albertov 4, Prague 2:
Thursdays 13.00 - 14.30 - Lectures in the lecture hall of the Institute of Pharmacology (since 23. 10. 2025)
If you have any questions, do not hesitate to contact us.
MUDr. Nikolina Canová, Ph.D. (ncano@lf1.cuni.cz ), representative for teaching
prof. MUDr. Ondřej Slanař, Ph.D. (oslan@lf1.cuni.cz ), head of the department
Poslední úprava: Canová Nikolina, MUDr., Ph.D. (03.09.2025)
Sylabus - angličtina
Topics of lectures and seminars:
• Antihypertensives, pharmacotherapy of hypertension
• Antiobesity drugs
• Medicines that affect blood clotting
• Hypolipidemics
• Antiarrhythmics
• Antivirals
• Antibiotics
• Antidiabetics, insulins
• Pharmacotherapy of thyroid disorders
• Treatment of osteoporosis
• Immunopharmacology
• Cell and gene therapy, biological treatment
• Anticancer pharmacotherapy
• Remedies for respiratory diseases
• Pharmacotherapy of acute conditions
• Pharmacotherapy of pregnant women, lactating women, children and the elderly
• Drugs for diseases of the urogenital tract, drugs used in obstetrics
Poslední úprava: Kolářová Jana (08.03.2021)
Rozpis výuky -
Rozpis semestrální
Výukový týden
Datum
Od - Do
Typ výuky
Téma
Učitel
Soubory
Poznámka
Hodnocení
1
01.10.2025
14:15 - 16:00
přednáška
Pharmacotherapy of ischemic heart disease. Antiarrhythmic drugs.
The attendance is obligatory for all students.
MUDr. Nikolina Canová, Ph.D.
The attendance is obligatory for all students.
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
For lecture materials, please see File tab.
průměr: 4, hodnoceno: 5x
2
09.10.2025
14:15 - 16:00
přednáška
Heart failure. Diuretics. Therapy of hypertension.
The attendance is obligatory for all students.
MUDr. Nikolina Canová, Ph.D.
Seminars are canceled, however, the attendance at lectures is obligatory for all students.
The lecture is held in the lecture hall of the Institute of Pharmacology (2nd floor), Albertov 4, Prague 2, 128 00.
Lecture materials - see the "files" tab.
průměr: 4, hodnoceno: 4x
3
15.10.2025
14:15 - 16:00
přednáška
Antimicrobials I., II.
The attendance is obligatory for all students.
MUDr. Olga Bartošová, Ph.D.
The attendance is obligatory for all students.
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
For lecture materials, please see File tab.
průměr: 5, hodnoceno: 2x
4
21.10.2025
13:00 - 14:30
seminář
Pharmacotherapy of bacterial diseases - case reports.
Tuesdays from 01:00 PM to 02:30 PM – groups 4051 and 4052 + Erasmus
Note: The final program of seminars will always be determined by the teacher in connection with the dates of TDM teaching, lectures (and holiday days).
průměr: 4, hodnoceno: 2x
22.10.2025
14:45 - 16:15
seminář
Pharmacotherapy of bacterial diseases - case reports.
Wednesdays from 02:45 PM to 04:15 PM – groups 4053 and 4054
Note: The final program of seminars will always be determined by the teacher in connection with the dates of TDM teaching, lectures (and holiday days).
23.10.2025
13:00 - 14:30
přednáška
Antivirals, antifungals, antiparasitics.
doc. Danica Michaličková
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4, Prague 2, 128 00 (except 1/10 and 15/10/2025).
Lecture materials - see the "files" tab.
průměr: 5, hodnoceno: 2x
5
28.10.2025
13:00 - 14:30
seminář
Free day - SELF STUDY: OFF-LINE STUDY MATERIALS - Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
29.10.2025
14:45 - 16:15
seminář
Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
30.10.2025
13:00 - 14:30
přednáška
Anticoagulants and anti-platelet drugs; fibrinolytics and antifibrinolytics.
doc. Danica Michaličková
Lecture materials - see the "files" tab.
průměr: 5, hodnoceno: 2x
6
04.11.2025
13:00 - 14:30
seminář
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
05.11.2025
14:45 - 16:15
seminář
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
06.11.2025
13:00 - 14:30
přednáška
Hypolipidemics. An overview of the possibilities of pharmacological influence of the metabolic syndrome.
MUDr. Nikolina Canová, Ph.D.
Lecture materials - see the "files" tab.
7
11.11.2025
13:00 - 14:30
seminář
TDM (therapeutic drug monitoring) - separate schedule.
12.11.2025
14:45 - 16:15
seminář
TDM (therapeutic drug monitoring) - separate schedule.
13.11.2025
13:00 - 14:30
přednáška
Overview of hypothalamic-pituitary hormones. Corticosteroids.
MUDr. Olga Bartošová, Ph.D.
Lecture materials - see the "files" tab.
8
18.11.2025
13:00 - 14:30
seminář
Hypertension therapy overview + case reports
19.11.2025
14:45 - 16:15
seminář
Hypertension therapy overview + case reports
20.11.2025
13:00 - 14:30
přednáška
Drugs used in diseases of the respiratory system.
doc. Danica Michaličková
Lecture materials - see the "files" tab.
9
25.11.2025
13:00 - 14:30
seminář
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction
26.11.2025
14:45 - 16:15
seminář
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction
27.11.2025
13:00 - 14:30
přednáška
Drugs used in diseases of gastrointestinal tract.
MUDr. Nikolina Canová, Ph.D.
Lecture materials - see the "files" tab.
10
02.12.2025
13:00 - 14:30
seminář
Pharmacotherapy of respiratory tract system diseases - case reports.
03.12.2025
14:45 - 16:15
seminář
Pharmacotherapy of respiratory tract system diseases - case reports.
04.12.2025
13:00 - 14:30
přednáška
Cell and gene therapy, biological treatment. Immunopharmacology
prof. MUDr. Ondřej Slanař, Ph.D.
Lecture materials - see the "files" tab.
11
09.12.2025
13:00 - 14:30
seminář
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
10.12.2025
14:45 - 16:15
seminář
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
Pharmacotherapy in rheumatology: rheumatoid arthritis, osteoarthritis, gout.
17.12.2025
14:45 - 16:15
seminář
Pharmacotherapy in rheumatology: rheumatoid arthritis, osteoarthritis, gout.
18.12.2025
13:00 - 14:30
přednáška
Drugs used to treat diseases of the urogenital tract, drugs used in obstetrics.
MUDr. Olga Bartošová, Ph.D.
Lecture materials - see the "files" tab.
13
06.01.2026
13:00 - 14:30
seminář
Repetition of psychotropic drugs.
07.01.2026
14:45 - 16:15
seminář
Repetition of psychotropic drugs.
08.01.2026
13:00 - 14:30
přednáška
Pharmacotherapy in pregnant women, breastfeeding, children and the elderly.
MUDr. Karolína Hronová, Ph.D.
Lecture materials - see the "files" tab.
14
13.01.2026
13:00 - 14:30
seminář
Test - psychotropic drugs. Repetition of prescription writing.
14.01.2026
14:45 - 16:15
seminář
Test - psychotropic drugs. Repetition of prescription writing.
15.01.2026
13:00 - 14:30
přednáška
Drugs in palliative therapy
MUDr. Olga Bartošová, Ph.D.
Lecture materials - see the "files" tab.
15
20.01.2026
13:00 - 14:30
seminář
Pharmacotherapy of acute conditions – case studies. CREDIT
21.01.2026
14:45 - 16:15
seminář
Pharmacotherapy of acute conditions – case studies. CREDIT
22.01.2026
13:00 - 14:30
přednáška
Acute and chronic drug intoxication – treatment and antidotes.
prof. MUDr. Ondřej Slanař, Ph.D.
Lecture materials - see the "files" tab.
Schedule semestral
Educational week
Date
From - To
Education type
Theme
Teacher
Files
Note
Hodnocení
1
01.10.2025
14:15 - 16:00
lecture
Pharmacotherapy of ischemic heart disease. Antiarrhythmic drugs.
The attendance is obligatory for all students.
MUDr. Nikolina Canová, Ph.D.
The attendance is obligatory for all students.
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
For lecture materials, please see File tab.
průměr: 4, hodnoceno: 5x
2
09.10.2025
14:15 - 16:00
lecture
Heart failure. Diuretics. Therapy of hypertension.
The attendance is obligatory for all students.
MUDr. Nikolina Canová, Ph.D.
Seminars are canceled, however, the attendance at lectures is obligatory for all students.
The lecture is held in the lecture hall of the Institute of Pharmacology (2nd floor), Albertov 4, Prague 2, 128 00.
Lecture materials - see the "files" tab.
průměr: 4, hodnoceno: 4x
3
15.10.2025
14:15 - 16:00
lecture
Antimicrobials I., II.
The attendance is obligatory for all students.
MUDr. Olga Bartošová, Ph.D.
The attendance is obligatory for all students.
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
For lecture materials, please see File tab.
průměr: 5, hodnoceno: 2x
4
21.10.2025
13:00 - 14:30
seminar
Pharmacotherapy of bacterial diseases - case reports.
Tuesdays from 01:00 PM to 02:30 PM – groups 4051 and 4052 + Erasmus
Note: The final program of seminars will always be determined by the teacher in connection with the dates of TDM teaching, lectures (and holiday days).
průměr: 4, hodnoceno: 2x
22.10.2025
14:45 - 16:15
seminar
Pharmacotherapy of bacterial diseases - case reports.
Wednesdays from 02:45 PM to 04:15 PM – groups 4053 and 4054
Note: The final program of seminars will always be determined by the teacher in connection with the dates of TDM teaching, lectures (and holiday days).
23.10.2025
13:00 - 14:30
lecture
Antivirals, antifungals, antiparasitics.
doc. Danica Michaličková
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4, Prague 2, 128 00 (except 1/10 and 15/10/2025).
Lecture materials - see the "files" tab.
průměr: 5, hodnoceno: 2x
5
28.10.2025
13:00 - 14:30
seminar
Free day - SELF STUDY: OFF-LINE STUDY MATERIALS - Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
29.10.2025
14:45 - 16:15
seminar
Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
30.10.2025
13:00 - 14:30
lecture
Anticoagulants and anti-platelet drugs; fibrinolytics and antifibrinolytics.
doc. Danica Michaličková
Lecture materials - see the "files" tab.
průměr: 5, hodnoceno: 2x
6
04.11.2025
13:00 - 14:30
seminar
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
05.11.2025
14:45 - 16:15
seminar
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
06.11.2025
13:00 - 14:30
lecture
Hypolipidemics. An overview of the possibilities of pharmacological influence of the metabolic syndrome.
MUDr. Nikolina Canová, Ph.D.
Lecture materials - see the "files" tab.
7
11.11.2025
13:00 - 14:30
seminar
TDM (therapeutic drug monitoring) - separate schedule.
12.11.2025
14:45 - 16:15
seminar
TDM (therapeutic drug monitoring) - separate schedule.
13.11.2025
13:00 - 14:30
lecture
Overview of hypothalamic-pituitary hormones. Corticosteroids.
MUDr. Olga Bartošová, Ph.D.
Lecture materials - see the "files" tab.
8
18.11.2025
13:00 - 14:30
seminar
Hypertension therapy overview + case reports
19.11.2025
14:45 - 16:15
seminar
Hypertension therapy overview + case reports
20.11.2025
13:00 - 14:30
lecture
Drugs used in diseases of the respiratory system.
doc. Danica Michaličková
Lecture materials - see the "files" tab.
9
25.11.2025
13:00 - 14:30
seminar
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction
26.11.2025
14:45 - 16:15
seminar
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction
27.11.2025
13:00 - 14:30
lecture
Drugs used in diseases of gastrointestinal tract.
MUDr. Nikolina Canová, Ph.D.
Lecture materials - see the "files" tab.
10
02.12.2025
13:00 - 14:30
seminar
Pharmacotherapy of respiratory tract system diseases - case reports.
03.12.2025
14:45 - 16:15
seminar
Pharmacotherapy of respiratory tract system diseases - case reports.
04.12.2025
13:00 - 14:30
lecture
Cell and gene therapy, biological treatment. Immunopharmacology
prof. MUDr. Ondřej Slanař, Ph.D.
Lecture materials - see the "files" tab.
11
09.12.2025
13:00 - 14:30
seminar
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
10.12.2025
14:45 - 16:15
seminar
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
