SubjectsSubjects(version: 978)
Course, academic year 2025/2026
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Cell Biology for teachers - MB150P73
Title: Biologie buňky pro učitelské kombinace
Czech title: Biologie buňky pro učitelské kombinace
Guaranteed by: Department of Cell Biology (31-151)
Faculty: Faculty of Science
Actual: from 2024
Semester: winter
E-Credits: 3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, Ex [HT]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Note: enabled for web enrollment
priority enrollment if the course is part of the study plan
Guarantor: RNDr. Nataša Šebková, Ph.D.
Teacher(s): RNDr. Nataša Šebková, Ph.D.
Incompatibility : MB150P31
Is co-requisite for: MB150C28U
Is incompatible with: MB151P95
Is complex co-requisite for: MB150C28, MB150P04A
In complex pre-requisite: MB150P22, MB152P02
Annotation -
Please note, the lectures are given in czech language only.



Last update: Šebková Nataša, RNDr., Ph.D. (12.10.2021)
Literature - Czech

Alberts et al.: Základy buněčné biologie - Úvod do molekulární biologie buňky (orig. Essential Cell Biology. Garland Publishing, Inc. NY, 1st edition, 1997) 2001 (ISBN 80-902906 -0-4).

Alberts et al.: Molecular Biology of the Cell. 3rd ed., 1994 (ISBN 0-8153-1919-4), 4th ed., 2002 (ISBN 0-8153-4072-9).
Lodish et al.: Molecular Cell Biology. 3rd ed., 1995 (ISBN 0-7167-2380), 4th ed., 2000 , 5th ed., 2004 (ISBN 0-7167-4366-3).
Alberts et al.: Essential Cell Biology. 1st ed., 1998 (ISBN 0-8153-2045-0 Hardcover,
ISBN 0-8153-2971-7 Paperback). 2nd ed. 2003 (ISBN 0-8153-3480-X).
Pollard T.D.: Cell Biology. 1st ed., 2002 (ISBN 0-7216-3997-6).
Kovář J.: Buněčná proliferace a mechanismy její regulace I. a II. Karolinum 1998 a 1999.
Středoškolská učebnice se shodným tematem..

Last update: Šebková Nataša, RNDr., Ph.D. (12.10.2021)
Requirements to the exam -

Examination of Cell Biology for the teacher combination will take the form of a written test. Each test will be multiple choice test, contains 20 questions. Test also includes 2 questions, students will answer in writing.
For each correctly answered question 1 to 20 counts four points, for two correct 2 points, for one correct one point. For the correct answer in the written part student receives 5 points. In the test, it is possible to reach a maximum of 90 points. To meet the test student must receive a minimum of 60 points.

Last update: Šebková Nataša, RNDr., Ph.D. (12.10.2021)
Syllabus -

- Types and structure of viruses, interaction with the host cell; life cycle

- Types and structure of cells; cell organelles and their functions; comparison of bacterial, archaeal and eukaryotic cells; mitochondria and chloroplasts - structure, semiautonomy, evidence of origin; ubiquitin-proteasome system; proteins and their structures

- Anatomy and function of the cell nucleus - structure of the nucleus, organization of genetic information, chromatin, chromosome, structure and function of DNA, utilization of genetic information

- Membranes and transport - structure and function of the biomembrane, its properties; function of membrane proteins; membrane potential; cell cortex; glycocalyx; receptors; transmembrane transport of substances; types of transport; osmosis

- Intracellular compartments and transport - entry of proteins into membrane organelles; vesicular transport; secretion and membrane trafficking - endocytosis and exocytosis

- Cellular metabolism - catalysis and energy utilization by cells; coupled reactions, biological oxidations; breakdown of sugars and fats; mitochondria and chloroplasts - role in cellular energy balance; photosynthesis

- Cytoskeleton - microtubules, microfilaments, intermediate filaments, septins; structure and function, organizational centres; associated proteins; molecular mechanisms of movement - molecular motors and intracellular transport, types of cell movement, cilia, flagella, amoeboid movement, muscle contraction, interaction of cells with the extracellular matrix; bacterial cytoskeleton

- Cell division - cell proliferation, cell cycle and its phases, mitotic spindle, specifics of plant cells, nuclear division and cytokinesis, mechanisms of cell cycle regulation, apoptosis, tumor growth

- Cell-to-cell communication - types of signalling, membrane and nuclear receptors, major classes of cell surface receptors, intracellular signal transducers, molecular switches, signalling cascades and their integration, regulation, disorders and their consequences

- Extracellular matrix and cell junctions - plant cell wall, structure, properties, function, synthesis; bacterial cell wall; extracellular matrix of animal cells, epithelia and intercellular junctions; interaction of cells with extracellular matrix

 - Immune system - functions and components of the immune system; specific, non-specific immunity; MHC glycoproteins; immune responses based on T and B lymphocytes, NK cells and antibodies - T and B cell activation, clonal selection, inflammation

Last update: Šebková Nataša, RNDr., Ph.D. (27.03.2025)
Learning outcomes -

Learning Outcomes

1. Viruses

Knowledge:
The student knows the basic types of viruses, their structure, replication strategies, and life cycles.

Skills:
The student explains virus–host cell interactions and distinguishes between different viral life cycles.

Competences:
The student is able to assess the significance of viral infections in cellular biology and medicine.

Bloom’s taxonomy: Remembering – Understanding – Evaluating

2. Cell Types and Organelles

Knowledge:
The student knows the structure of bacterial, archaeal, and eukaryotic cells and the functions of major cellular organelles.

Skills:
The student compares different cell types with respect to their structure and function.

Competences:
The student applies this knowledge to interpret biological processes in different organisms.

Bloom’s taxonomy: Remembering – Analyzing – Applying

3. Mitochondria and Chloroplasts

Knowledge:
The student knows the structure and functions of mitochondria and chloroplasts.

Skills:
The student explains their semi-autonomy and summarizes evidence supporting their endosymbiotic origin.

Competences:
The student integrates this knowledge to explain the cellular energy balance.

Bloom’s taxonomy: Understanding – Creating (Synthesizing)

4. Cell Nucleus and Genetic Information

Knowledge:
The student knows the structure of the cell nucleus, chromatin organization, DNA structure, and the genetic code.

Skills:
The student explains the flow of genetic information according to the central dogma of molecular biology.

Competences:
The student interprets fundamental molecular genetic processes in the cell.

Bloom’s taxonomy: Understanding – Applying

5. Biomembranes and Transport

Knowledge:
The student knows the composition and properties of biological membranes, membrane proteins, and transport mechanisms.

Skills:
The student applies this knowledge to explain passive and active transport, osmosis, and membrane potential.

Competences:
The student analyzes the impact of changes in membrane properties on cellular function.

Bloom’s taxonomy: Understanding – Applying – Analyzing

6. Intracellular Compartments and Transport

Knowledge:
The student knows the principles of protein targeting and vesicular transport.

Skills:
The student distinguishes and describes endocytosis and exocytosis.

Competences:
The student explains the relationship between compartmentalization and functional specialization of the cell.

Bloom’s taxonomy: Understanding – Analyzing

7. Cellular Metabolism

Knowledge:
The student knows the basic metabolic pathways, principles of catalysis, and biological oxidations.

Skills:
The student explains the role of mitochondria and chloroplasts in energy metabolism and photosynthesis.

Competences:
The student applies metabolic knowledge to explain cellular energy demands.

Bloom’s taxonomy: Understanding – Applying

8. Cytoskeleton and Cell Motility

Knowledge:
The student knows the types of cytoskeletal filaments and their associated proteins.

Skills:
The student analyzes cytoskeletal functions in intracellular transport and cell motility.

Competences:
The student interprets the role of the cytoskeleton in cell–environment interactions.

Bloom’s taxonomy: Analyzing – Creating (Synthesizing)

9. Cell Cycle and Cell Death

Knowledge:
The student knows the phases of the cell cycle, mechanisms of its regulation, and types of cell death.

Skills:
The student explains the differences between apoptosis and necrosis and their biological significance.

Competences:
The student evaluates the relationship between cell cycle dysregulation and tumor growth.

Bloom’s taxonomy: Understanding – Evaluating

10. Cell Communication

Knowledge:
The student knows the basic types of cell signaling and the major classes of receptors.

Skills:
The student analyzes signaling pathways and their integration within the cell.

Competences:
The student evaluates the consequences of signaling defects for cellular and organismal function.

Bloom’s taxonomy: Analyzing – Evaluating

11. Extracellular Matrix and Immunity

Knowledge:
The student knows the structure and functions of the extracellular matrix, cell junctions, and key components of the immune system.

Skills:
The student explains cell–extracellular matrix interactions and the principles of immune responses.

Competences:
The student integrates knowledge of cell biology and immunology to explain tissue organization and immune defense.

Bloom’s taxonomy: Creating (Synthesizing) – Evaluating

Last update: Šebková Nataša, RNDr., Ph.D. (26.12.2025)
 
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