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Course, academic year 2023/2024
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Immunology - GAF143
Title: Immunology
Guaranteed by: Department of Biological and Medical Sciences (16-16150)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2023
Semester: winter
Points: 0
E-Credits: 4
Examination process: winter s.:combined
Hours per week, examination: winter s.:42/14, C+Ex [HS]
Capacity: unlimited / 60 (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Explanation: (F,2.r.)
Note: deregister from the exam date if a requisite was not fulfilled
course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: PharmDr. Jana Urbánková Rathouská, Ph.D.
Classification: Health Care > Clinical Disciplines
Comes under: 2.ročník 2023/24 Pharmacy (EN19)
Co-requisite : GAF181
Pre-requisite : GAF366
Is co-requisite for: GAF234, GAF181
Is pre-requisite for: GAF305
Annotation -
Immunology is an integral part of a set of disciplines focused on understanding the biological nature of humans. The main aim of the course is to introduce students to the principles of the functioning of the immune system as a whole, with its role in homeostasis, both under physiological and pathological conditions. The practical implications of immunological research are also emphasized, especially in the field of medical laboratory methodology and in the prevention and therapy of a number of diseases. As graduates of the Faculty of Pharmacy have been successful in both clinical and experimental immunology, this discipline is conceived as one of the options for future professional employment.
Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (19.02.2024)
Course completion requirements

 Attaining a credit and passing exam.
 For the credit it is necessary to complete the exercises without unexcused absences, to pass successfully the credit test and to submit protocols rated 2 and better.

 The exam consists of a multiple choice test, a written miniassay and an oral part of the exam. The evaluation of all three parts is complex.











Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (21.09.2023)
Literature - Czech


Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (21.09.2023)
Syllabus -
  • The structure of the immune system: cells, lymphoid organs, lymphatic vessels
  • Ontogeny and phylogeny of immunity
  • Antigens, molecules recognizing antigens specifically, immunoglobulins, the generation of diversity of antibodies, T-cell antigen receptors
  • Major histocompatibility complex, immunogenetics
  • Antigen-antibody reaction, basic immunochemistry, principles of serology
  • Adaptive immunity, immunological memory, immunity to microbes; principles of vaccination
  • Antitumour immunity, mechanisms of graft rejection
  • Immunological tolerance
  • Innate immunity: phagocytosis, complement, inflammation.
  • Regulation in the immune system, co-operation of cells of immune system, cytokine network, the role of the immune system in homeostasis
  • Immunopathology: allergy and hypersensitivity, autoimmune diseases, immunodeficiency, AIDS
  • Principles of immunological methods, their application in pharmacy
  • Immunoglobulins, molecules specifically recognizing antigen
  • Immunonological memory, principles of vaccines
  • Introduction in the laboratory methods like: testing of phagocytic activity, assays for estimation of complement activity, assessment of lysozyme and C-reactive protein, precipitation in gels, immunoelectrophoresis, basic serological tests, immunoenzymatic and immunofluorescence assays, MHC matching, flow cytometry
Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (21.09.2023)
Teaching methods
Lectures, exercises with practical part, seminar, self-study with the use of recommended literature and materials for lectures.
Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (21.09.2023)
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