SubjectsSubjects(version: 953)
Course, academic year 2023/2024
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Immunopharmacology - GAF234
Title: Immunopharmacology
Guaranteed by: Department of Biological and Medical Sciences (16-16150)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2023
Semester: summer
Points: 0
E-Credits: 3
Examination process: summer s.:combined
Hours per week, examination: summer s.:28/14, C+Ex [HS]
Capacity: unlimited / unlimited (30)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Explanation: (F 3.r.)
Note: deregister from the exam date if a requisite was not fulfilled
course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: PharmDr. Jana Urbánková Rathouská, Ph.D.
Co-requisite : GAF143
Annotation -
Immunopharmacology (rarely lectured in Europe) extends knowledge of the subject of immunology and responds to the rapid development of immune modulating drugs. These include, in particular, medicines used in transplant medicine, allergy and clinical immunology, and immunomodulation procedures applied in oncology. In particular, issues of immunity and vaccine prevention, as well as the side immunotoxic and allergenic effects of other drugs and xenobiotics are discussed. Attention is also paid to the relationship between immune and neurohumoral regulation systems, the influence of stress, nutrition and the environment on immunity. Practical aspects of immunopharmacological therapy are presented. Students have the opportunity to study in detail the specific problem of immunopharmacotherapy and thus gain experience in the field of medical informatics.
Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (19.02.2024)
Course completion requirements

Attaining a credit and passing exam.
For the credit, it is necessary to complete the exercises without unauthorized absences and presentation of one seminar topic.

The exam consists of a multiple choice test, a written miniassay and an oral test. The evaluation of all three parts is complex.


Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (19.02.2024)
Literature - Czech


  • Nijkamp P., Parnham M. J (Eds.). Principles of Immunopharmacology. Berlin: Springer, 2011, 728 s. ISBN 978-3-0346-0136-8.


  • Klein, Jan, Hořejší, Václav. Immunology. Oxford: Blackwell, 1999, 722 s. ISBN 0-632-05468-9.


  • Rich, Robert R. (ed.). Clinical immunology : principles and practice. London: Mosby Company, 2001, 63 s. ISBN 0-7234-3161-2.

Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (19.02.2024)
Syllabus -
  • Active immunization, vaccines technology, perspective vaccines, means of passive immunization, antibodies in therapy, monoclonal antibodies, immunoconjugates - specific drug targeting, immunotoxins.

  • Therapeutic use of cytokines, immunomodulators of microbial origin, thymic hormones and synthetic immunostimulators.

  • Drugs for immunosupressive therapy: corticosteroids, antimetabolites and calcineurine inhibitors.

  • Therapy and prevention of allergic diseases and drug hypersensitivity.

  • Relationships between immune and neurohumoral regulations, influence of stress, nutrition and environment on immunity.

  • Basic immunotoxicology - principles of testing of immunomodulating and immunotoxicological properties of drugs and xenobiotics.

  • Clinical aspects of antiallergic, immunosuppressive, immunostimulating and substitutive therapy.

Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (19.02.2024)
Learning resources
Essential supports are given in each lecture and are also discussed in seminars.
Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (19.02.2024)
Teaching methods
Lectures, seminars, self-study with the use of recommended literature and supporting materials.
Last update: Urbánková Rathouská Jana, PharmDr., Ph.D. (19.02.2024)
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