This subject focuses on educating students in biomedical research and biotechnologies. It teaches the basis of
scientific work, introduction to methodology in biomedicine up to the development of novel diagnostics and
therapeutics. Lectures and seminars will contain the insight into modern tools such as transgenic biology or
global technologies such as OMICs.
Poslední úprava: Marcela Holanová (01.02.2023)
This subject focuses on educating students in biomedical research and biotechnologies. It teaches the basis of
scientific work, introduction to methodology in biomedicine up to the development of novel diagnostics and
therapeutics. Lectures and seminars will contain the insight into modern tools such as transgenic biology or
global technologies such as OMICs.
Metody výuky
Poslední úprava: Ing. Lucie Vyšatová (31.01.2024)
Lectures will be held in BIOCEV (Seminary Room U2.020 - Průmyslová 595, 252 50 Vestec) starting February 22nd 2024 from 4 pm. In case of questions, please do not hesitate to contact Lucie Vyšatová (lucie.vysatova@lf1.cuni.cz).
Rozpis výuky -
Rozpis datumový
Den
Datum
Popis
Učitel
Soubory
Poznámka
Hodnocení
Čtvrtek
22.02.2024
Title: Protein engineering in biomedicine
State-of-the-art protein engineering is progressively asserting itself in biomedicine in a plethora of tasks such as adjustment, amplification, or attenuation of immune responses, development of new diagnostic and therapeutic modalities, and strategies to treat multiple infectious, autoimmune, and neoplastic diseases.
RNDr. Jiří Zahradník, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Čtvrtek
07.03.2024
Title: Tumor ecosystem
Tumors are composed of cancer cells as well as non-malignant cells such as infiltrating leukocytes and cancer-associated fibroblasts. These non-malignant cells participate in the control of cancer cell differentiation, proliferation and migration via extensive intercellular dialogue utilizing the paracrine secretion of many bioactive factors. The principle of their activity will be shown as an example of cancer-associated fibroblasts.
prof. MUDr. Karel Smetana, DrSc.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Čtvrtek
21.03.2024
Title: CLINICAL PROTEOMICS
Using efficient separation methods and high-resolution mass spectrometry PROTEOMICS enables monitoring of quantitative and qualitative changes of thousands of proteins in biological samples. Detailed knowledge of proteome changes in cells and tissues can elucidate molecular mechanisms of physiologic and pathologic processes, and identify disease markers or novel therapeutic targets.
doc. RNDr. Jiří Petrák, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Čtvrtek
04.04.2024
Title: CELL BIOLOGY : Stem cell biology versus proliferation and differentiation control
Regulatory mechanisms in normal cell differentiation including transcription factors and their effector pathways. Biology of stem cells and tissue transplantation. Regulation of cell cycle and its detection.
prof. MUDr. Tomáš Stopka, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Čtvrtek
18.04.2024
Title: Biology of solid tumors and translational medicine
Basic principles of cancer development, cancer driver mutations and targeted therapy, cancer evolution and progression, cancer cell dormancy and invasiveness, circulating tumor cells.
RNDr. Radoslav Janoštiak, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Čtvrtek
02.05.2024
Title: GENETICS : Cancer genomes and genome editing technology
Cancer associated acquired DNA mutations and their role in tumor development, progression, and therapy resistance. Consequences for interaction of tumor cells with immune system. Use of genome modifying technologies to create models for cancer research and options for therapy.
doc. MUDr. Ondřej Havránek, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Čtvrtek
16.05.2024
Title: Leukocyte migration and immunology
Migration of leukocytes in healthy and pathological states. Imaging of leukocyte behaviour and interactions. Cell biology of leukocyte motility.
Mgr. Miroslav Hons, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Čtvrtek
30.05.2024
Title: Redox Biology
Reactive oxygen and nitrogen species are not just harmful by-products that cause damage to macromolecules and ultimately cell death. They are essential signaling molecules that play a role in basic biological processes, so-called "redox signaling". The basic principles of redox signalling, its role in physiological cellular processes and in cancer will be discussed.
RNDr. Kristýna Pimková, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Schedule by date
Day
Date
Description
Teacher
Files
Note
Hodnocení
Thursday
22.02.2024
Title: Protein engineering in biomedicine
State-of-the-art protein engineering is progressively asserting itself in biomedicine in a plethora of tasks such as adjustment, amplification, or attenuation of immune responses, development of new diagnostic and therapeutic modalities, and strategies to treat multiple infectious, autoimmune, and neoplastic diseases.
RNDr. Jiří Zahradník, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Thursday
07.03.2024
Title: Tumor ecosystem
Tumors are composed of cancer cells as well as non-malignant cells such as infiltrating leukocytes and cancer-associated fibroblasts. These non-malignant cells participate in the control of cancer cell differentiation, proliferation and migration via extensive intercellular dialogue utilizing the paracrine secretion of many bioactive factors. The principle of their activity will be shown as an example of cancer-associated fibroblasts.
prof. MUDr. Karel Smetana, DrSc.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Thursday
21.03.2024
Title: CLINICAL PROTEOMICS
Using efficient separation methods and high-resolution mass spectrometry PROTEOMICS enables monitoring of quantitative and qualitative changes of thousands of proteins in biological samples. Detailed knowledge of proteome changes in cells and tissues can elucidate molecular mechanisms of physiologic and pathologic processes, and identify disease markers or novel therapeutic targets.
doc. RNDr. Jiří Petrák, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Thursday
04.04.2024
Title: CELL BIOLOGY : Stem cell biology versus proliferation and differentiation control
Regulatory mechanisms in normal cell differentiation including transcription factors and their effector pathways. Biology of stem cells and tissue transplantation. Regulation of cell cycle and its detection.
prof. MUDr. Tomáš Stopka, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Thursday
18.04.2024
Title: Biology of solid tumors and translational medicine
Basic principles of cancer development, cancer driver mutations and targeted therapy, cancer evolution and progression, cancer cell dormancy and invasiveness, circulating tumor cells.
RNDr. Radoslav Janoštiak, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Thursday
02.05.2024
Title: GENETICS : Cancer genomes and genome editing technology
Cancer associated acquired DNA mutations and their role in tumor development, progression, and therapy resistance. Consequences for interaction of tumor cells with immune system. Use of genome modifying technologies to create models for cancer research and options for therapy.
doc. MUDr. Ondřej Havránek, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Thursday
16.05.2024
Title: Leukocyte migration and immunology
Migration of leukocytes in healthy and pathological states. Imaging of leukocyte behaviour and interactions. Cell biology of leukocyte motility.
Mgr. Miroslav Hons, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
Thursday
30.05.2024
Title: Redox Biology
Reactive oxygen and nitrogen species are not just harmful by-products that cause damage to macromolecules and ultimately cell death. They are essential signaling molecules that play a role in basic biological processes, so-called "redox signaling". The basic principles of redox signalling, its role in physiological cellular processes and in cancer will be discussed.
RNDr. Kristýna Pimková, Ph.D.
Students are encouraged to read education material ahead of the seminar available at: https://biocev.lf1.cuni.cz/vyuka
