The goal of the elective program is to introduce the methods used in selected areas of basic and clinical pharmacology including modern trends. The course includes practical training of the methods using computers and case studies from clinical practice.
Poslední úprava: Kalhousová Hana (05.02.2019)
Literatura - angličtina
Recommend literature
Goodman & Gilman's The Pharmacological Basis of Therapeutics. 11 edition. McGraw-Hill Professional 2005 (ISBN-10: 0071422803).
The presence on lectures and active participation in seminars and practicals is required (maximum 20% of absence); in the case of 2 and more absences, the student will be asked to create the short communication on a selected topic.
Poslední úprava: Kalhousová Hana (05.02.2019)
Sylabus - angličtina
Lectures
Classical and new molecular targets for drugs, traditional and modern approaches to drug development. (Chladek 3)
Basic terms in pharmacoepidemiology and pharmacoeconomics. Comparative drug studies, trials of pharmacotherapeutic intervention, principles of evidence based medicine in pharmacology, pharmacotherapeutic guidelines, systematic reviews and meta-analyses. (Chladek 3)
Practical courses & seminars
Lecturers
Assoc. Prof. Jaroslav Chladek, M.Sc., Ph.D.
Assoc. Prof. Martin Štěrba, PharmD., Ph.D.
The role of "OMICS" technologies in pharmacological research: genomics, proteomics, transcriptomics and metabolomics (seminar).
New trends in pharmacokinetics (PK/PD) and pharmacodynamics, PK/PD of therapeutic proteins (seminar). PK/PD modelling (practical).
Population pharmacokinetics/pharmacodynamics and its value for personalized pharmacotherapy (seminar). Population PK/PD models for selected drugs (practical).
