PředmětyPředměty(verze: 945)
Předmět, akademický rok 2023/2024
   Přihlásit přes CAS
Physiology I - FD10019
Anglický název: Physiology I
Zajišťuje: Ústav fyziologie (15-130)
Fakulta: Lékařská fakulta v Hradci Králové
Platnost: od 2021
Semestr: zimní
Body: 0
E-Kredity: 7
Způsob provedení zkoušky: zimní s.:
Rozsah, examinace: zimní s.:33/72, Z [HS]
Počet míst: neomezen
Minimální obsazenost: neomezen
4EU+: ne
Virtuální mobilita / počet míst pro virtuální mobilitu: ne
Kompetence:  
Stav předmětu: nevyučován
Jazyk výuky: angličtina
Způsob výuky: prezenční
Způsob výuky: prezenční
Úroveň:  
Garant: prof. MUDr. Michaela Adamcová, Ph.D.
Neslučitelnost : FZ10017
Prerekvizity : FD10003
Záměnnost : FA0203037, FZ10017
Je korekvizitou pro: FD50006, FD10020
Je neslučitelnost pro: FZ10017
Je prerekvizitou pro: FD10031, FD10033, FD10030
Je záměnnost pro: FZ10017
Ve slož. prerekvizitě: FD10048
Termíny zkoušek   Rozvrh   
Anotace - angličtina
Poslední úprava: Ivana Altmannová (17.09.2021)
To gain a good theoretical knowledge in following fileds of medical physiology: regulation of body functions, haematology, immunology, general neurophysiology (transport of ions across cell membrane, resting membrane and action potential), myology, central nervous system (spinal cord reflexes, control of posture and movement, the autonomic nervous system, function of single parts of CNS, sleep and wakefulness, higher nervous functions), cardiovascular system. To gain basal practical skill in haematological laboratory examination, in physical examination of the cardiovascular system, and in investigation of sense functions. Using computer simulation to demonstrate basic electro-physiological principles. To learn how to gain scientific information.
Požadavky ke zkoušce - angličtina
Poslední úprava: Ivana Altmannová (20.09.2021)

Practical classes

Students come properly prepared for performing the planned practical task(s) and knowing the theory immediately related to the task(s). Extent of theoretical knowledge necessary for practical class is outlined by a techaer. Extent of practical preparedness is given by the Manuals for the Practical Classes in Physiology or by instruction manuals published via Moodle, alternatively it might by also outlined by a teacher. If a serious negligence of preparedness is revealed by the assistant, such student is dismissed from practical class and an absence is recorded. Entry to the Department of Physiology will not be allowed to students with obvious signs of an illness and symptoms of acute infectious disease (e.g. body temperature equal to or exceeding 37oC, cough, shortness of breath etc.). Body tempreature might be checked by contactless thermometer. It not stated otherwise, there is a ban on using personal electronic devices (mobile phones, recorders etc.) during practiccal classes. Failure to comply with this rule will be supervised by the Head of the Department of Physiology. Late coming irrespcetive of reason or deliberately leaving class earlier will be considered and recorded as absence. The organization of the practical classes may change in the light of the current epidemic situation and the regulations in force.

 

Protocols


Only in case of onsite tuition, each student has to record results and discussion of every performed practical task in the specified room in Manuals for the Practical Classes in Physiology. This shall be completed before leaving each onsite class, if not agreed on otherwise with the teacher. Students have to follow the arrangement of the records in the Manuals and fill in all expected data. The emphasis lies on capturing the results and analysing them. Erroneous results are accepted, however students are required to provide suggestions on the reason of flaws. In case of remote practical tuition, notes made in the Manuals may be replaced by different handouts provided to students for completing or solving.

 

Seminars

Seminars are intended for deeper repetition of current topic and student consultations with the teacher. Students are asked to select some of the published themes and deliver short oral presentations. We recommend booking at least 3 themes for each seminar with each presentation lasting up to 10 - 15 minutes. Each contribution is followed by discusion. An integral part of the seminar is the test.

  

Obtaining a credit grade

Credit will be given to the students, who fulfil the attendance requirements, have passed the tests in each of the individual physiology system in theat semester and have presented the completed practical class protocols. Each semester that contains phyisology ha a single credit, i.e. there are two credits. In epidemic situarion wil lnecessiate change in character of tuition, criteria for obtaining a credit grade might be amended accordingly.

Attendance:

Students are required to attend all practical (laboratory) classes. The number of absences must not exceed 15 % of all practical classes. If more that 15 % of practical classes per term are missed the reexamination from all practical classes in semester is required. If more than 40 % of practical classes per term are missed the situation will be supervised by the Head of the Deparmtne of Physiology.

Tests:

At the end of laboratory classes in each system, a seminar will be held during which the students will be tested on that system. In order to receive a credit, student must score at least "good" in all tests. The tests will be in the form of a multiple choice questionnaire. Those students who fail the test will take 1st correction test (the date will be announced in advance). There will be dates for 2nd correction at the end of winter and summer term, respectively. Third correction will be at the end of summer semester in the form of oral exam by a commission. Basic knowledge of recording and evaluation of ECG in general medicine students, will be tested, too. In order to receive a credit, student must score at least "good" in this test. The same rules mentioned above are applied for this test. If onsite tests will be impossible, students wil get instructions on alternative remote forms of testing ahead of time.

 

Final examination in physiology

For adminission to final examination students must receive credits in both winter and summer term and sign up for final examination (SIS system). The examination comprises an introductory test, then oral exam follows. Re-examination comprise only the oral part. The number of announced dates for a regular term considers the total number of studnets. More dates will be for the 1st or 2nd retake and will be announced regarding the current requirements.

Use of electronic devices (cell phones, tablets, notebooks etc.) unauthorized materials or communication with other students is strictly prohibited. After selecting final exam questions it is not allowed to leave the room and when necessary an escort will be provided. In case of failure co comply with these rules, students will be classified "fail" and cheating will be announced to the Disciplinary Committee of th Faculty.

Registration and re-registration can be done only through SIDS. Detailed information of the format of this examination will be posted on the bulletin board at the end of the summer term.

Sylabus - angličtina
Poslední úprava: Ivana Altmannová (20.09.2021)

Lecturers

  • Prof. Michaela Adamcová, M.D., Ph.D.
  • Prof. Milan Holeček, M.D., Ph.D.
  • Assoc. Prof. Otto Kučera, M.D., Ph.D.
  • Assoc. Prof. Halka Lotková, M.D., Ph.D.

 

 29. 9. 2021      Introduction to physiology (homeostasis and its regulation). (Adamcová 1)

 29. 9. 2021      Body fluid compartments. Composition of body fluids.  (Adamcová 1)

 29. 9. 2021      Function of blood. Physical constants of blood. Plasma.  (Adamcová 1)

 6. 10. 2021      Red blood cells. Hemolysis. Sedimentation of red cells. (Adamcová 1)

 6. 10. 2021      Haemoglobin. Regulation of red blood cell production - the role of erytropoietin. Essential substances required for erythropoiesis.  (Adamcová 1)

 6. 10. 2021      White blood cells. Regulation of white cell production. (Adamcová 1)

14. 10. 2021     Blood groups, blood transfusion. (Adamcová 1)

14. 10. 2021     Hemostasis (vessel reaction, importance of platelets, blood clotting, anticlotting mechanisms, anticoagulant drugs). (Adamcová 2)

21. 10. 2021     Immunology. Clasification of immune mechanisms (non-specific defence mechanisms, specific immune mechanisms, humoral and cell-mediated). Interactions between non-specific and specific immune mechanisms. Ontogenesis of immunity. Vaccination and passive immunity. 

                        Inflammation, allergy, auto-immunity. (Kučera 3)

22. 10. 2021     Resting membrane potential. Action potential. All-or-nothing principle. Chronaxy. (Adamcová 1)

22. 10. 2021     Excitation, propagation of action potential. Degeneration and regeneration of nerves, elektroneurogram. (Adamcová 1)

22. 10. 2021     Synaptic transmission. Excitatory and inhibitory post-synaptic potentials. Pre-synaptic inhibition and facilitation. Summation and occlusion. Classification of neurotransmitters. (Adamcová 1)

29. 10. 2021     Contraction of skeletal muscle. Neuromuscular junction of skeletal muscle. Energy source and metabolism of muscle contraction. Heat production in muscle. Excitation - contraction coupling. Muscle fatique. (Adamcová 1)

29. 10. 2021     Contraction and excitation of smooth muscle. Neuromuscular junctions of smooth muscle. Neural and hormonal control of smooth muscle contraction. (Adamcová 1)

29. 10. 2021     Spinal cord reflexes - proprioceptive stretch and tendon reflexes, exteroceptive reflexes, the role of muscle spindle and of gamma system, reciprocal innervation. (Holeček 1)   

  4. 11. 2021     Control of posture and movement - motor functions of spinal cord, cerebellum, basal ganglia, descendent part of reticular formation and brain. (Holeček 2)

  4. 11. 2021     Autoconomic nervous system. (Holeček 1)

  5. 11. 2021     Regulation of visceral function - the role of spinal cord, medulla oblongata, hypothalamus and limbic system in control of vegetative functions (vital centres, vomiting, hunger, thirst, sexual reactions, body temperature). Relation of hypthalamus to pituitary gland.  (Holeček 1)

  5. 11. 2021     The reticular activating system, spontaneous and evoked electric brain activity (EEG and evoked potentials). (Holeček 1)

  5. 11. 2021     Blood - brain barrier cerebrospinal fluid. Metabolism of the brain. (Holeček 1)

11. 11. 2021     CNS, inborn and acquired forms of behaviour, learning and memory. Emotion.  (Lotková 2)

11. 11. 2021     Specific characteristics of CNS in human (speech, hemispheric dominance, prefrontal lobes), types of personality. (Lotková 1)

18. 11. 2021     Action potential in cardiac muscle. Electrical and mechanical properties of cardiac muscle, conductive system. (Adamcová 1)

18. 11. 2021     Contraction of cardiac muscle. Excitation-contraction coupling. Homeostasis of calcium. Mechanical properties of heart, metabolism of cardiac muscle.  (Adamcová 1)

18. 11. 2021     The heart as a pump. The cardiac cycle. The main hemodynamic events associated with the cardiac cycle. Heart sounds. (Adamcová 1)

25. 11. 2021     ECG. (Adamcová 1)

25. 11. 2021     Cardiac output - method of measurment, regulation of output. (Adamcová 1)

25. 11. 2021     Dynamics of blood flow. Flow, pressure, and resistance. Laminar and turbulent flow. Poiseuille-Hagen formula. Criticial closing pressure. Law of Laplace. (Adamcová 1)

  9. 12. 2021     Functional parts of circulation of vessel, function of endothelium. Production of interstitial fluid, lymph. (Adamcová 2)

  9. 12. 2021     Local and systemic cardiovascular regulatory mechanisms. Cardiac innervation. The reflex mechanisms for maintaining normal arterial pressure. (Adamcová 1)

10. 12. 2021     Circulation through special regions (tooth pulp cerebral circulation, splanchnic, lung circulation, circulation of the skin, and of muscles). (Adamcová 2)

10. 12. 2021     Stimulus, receptor and generation potential, adaptation of receptors. (Adamcová 1)

16. 12. 2021     Vision. (Adamcová 2)

16. 12. 2021     Tactile sensation, perception of temperature and pain in the orofacial area. (Adamcová 1)

17. 12. 2021     Hearing and vestibular apparatus. (Adamcová 2)

17. 12. 2021     Smell and taste. (Adamcová 1)

 

Practical courses & seminars

Lecturers

  • Prof. Michaela Adamcová, M.D., Ph.D.
  • Prof. Zuzana Červinková, M.D., Ph.D.
  • Prof. Milan Holeček, M.D., D.Sc.
  • Assoc. Prof. Otto Kučera, M.D., Ph.D.
  • Assoc. Prof. Halka Lotková, M.D., Ph.D.
  • David Rychtrmoc, M.D., Ph.D.
  • Pavla Staňková, Mgr., Ph.D.
  • Václav Šafka, M.D., Ph.D.
  • Tumisand Edward Maseko, M.D.
  • Moustafa Elkalaf, MBBCh, Ph.D.

 

Seminars

  1. Test (MCQ) and seminar - hematology and immunology.
  2. Test (MCQ) and seminar -neurophysiology and myology.
  3. Test (MCQ) and seminar - central nervous system.
  4. Test (MCQ) and seminar - cardiovascular system.

Practical courses

  1. Introduction to practical laboratories. Rules of safety work in laboratories. Rules of blood handling and blood sampling.
  2. Packed cell volume (PCV - Hematocrit). Hemolysis. Testing of fragility of red blood cells.
  3. Investigation of capillary resistance. Investigation of bleeding time. Determination of clotting time (Lee-White), APTT, prothrombin time.
  4. Leukocytes - classification of white blood cells (differential count). Red blood cells sedimantation.
  5. Testing for blood group and Rh factor.
  6. Action potential (theory, case).
  7. Neuromuscular transmission (theory, case).
  8. Basic neurological examination - proprioceptive and exteroceptive reflexes.
  9. Autonomic nerve system - the role in the regulation of cardiovascular system.
  10. Physical examination of cardiovascular system. Determination of arterial blood pressure.
  11. ECG I.
  12. ECG II.
  13. Physical examination of cardiovascular system. Determination of arterial blood pressure.
  14. Harvard step test.
  15. Principles of the examination of vision.
  16. Principles of the examination of hearing. Investigation of vestibular function. Credit.

 

Literatura - angličtina
Poslední úprava: Ivana Altmannová (17.09.2021)

Compulsory literature

  1. Hall: Guyton and Hall Textbook of Medical Physiology, Elsevier 2016 (e-book)
  2. Cervinkova et al.: A Manual in Laboratory Studies in Physiology (obtained at the 1st practical class)

 

Recommended literature

  1. Silbernagl, Despopoulos: Color Atlas of Physiology, Georg Thieme Verlag, 2015 (e- book)
  2. Barrett: Ganong´s Review of Medical Physiology, Lange Medical Books, 2010

     

 

 

 

 

 
Univerzita Karlova | Informační systém UK