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This is a compulsory course that belongs among the basic courses of the core curriculum. Upon completion, students will have acquired knowledge and skills in the field of medical microbiology – in the description of individual microorganisms and their properties, in the principles of sampling, transport and processing of biological material, the mechanism of action and effect of antimicrobial agents, the general principles of anti-infective therapy, and the interaction of infectious agents with macroorganisms, which are essential prerequisites for further successful study in higher years. Within the framework of the course, students will acquire, for example, the following knowledge, skills, and competencies: - evaluate laboratory findings that could be related to diseases caused by microorganisms – abnormal leukocyte count, abnormal stool analysis results, occult bleeding, finding of parasites, abnormal urinary sediment, elevated markers of inflammation - understand basic pathological conditions that may be directly related to the action of microorganisms in the human body - e.g., lymphadenopathy, fever, chills, itching, swelling, edema, weight loss, acute severe headache, or meningism - understand the issue of nosocomial infections and their risks - antibiotic resistance, diagnostic and therapeutic options, cooperation with epidemiologists, barrier measures - understand the mechanisms of agent spread in the population, prevention of transmission routes, prevention - issues related to individual immunization – vaccination schedule; mandatory, optional, and recommended vaccinations - use basic clinical judgment when obtaining information relevant to patient treatment. Include scientific knowledge of theoretical medical sciences, including epidemiological information (incidence, prevalence), in clinical reasoning in order to compile a differential diagnosis - assess the severity of the patient's difficulties, symptoms of the disease, or the situation in which the patient finds themselves. Consult with other physicians and team members to confirm and approve the working diagnosis, explain and document the clinical reasoning that led to the working diagnosis; demonstrate critical thinking leading to the establishment of a differential diagnosis. - Recommend an initial, cost-effective diagnostic method for a patient with an acute or chronic illness, or as part of a preventive health examination. Evaluate test results and include them in the differential diagnosis. Understand the implications and urgency of abnormal test results and, if necessary, seek assistance in interpreting them. Poslední úprava: Hurych Jakub, MUDr., Ph.D. (17.02.2026)
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Microbiology I /summer/ Requirements for completing the semester: The requirement for completing the course is to receive a credit.
Requirements for receiving a credit in the summer semester: A credit will be awarded for: 1) participation in practical classes (2 absences outside of compulsory topics are permitted - see below) and 2) obtaining a minimum of 14/20 points from credit tests (written in weeks 6 and 13 during lectures in the Pelouch Hall):
3) Successful completion of the practical exam
The test results will be available online as soon as possible. In case of absence or insufficient points, the student will be tested orally by the relevant teacher during the credit week.
Compulsory topics - practical exercises in weeks 2, 3, and 4 cannot be replaced by self-study (see Dean's Measure No. 4/2022) and absences must be made up by attending practical exercises with another group, or the student will be examined by a group assistant. If absences from these exercises are not made up, credit cannot be awarded.
Poslední úprava: Hurych Jakub, MUDr., Ph.D. (17.02.2026)
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Murray, P. Medical microbiology : Mosby, 2009 (B), (avaible as ebook)
+Mims, C. A.: Medical microbiology : Mosby, 2013 Poslední úprava: Kovář Jan (01.07.2022)
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FOR BETTER RESOLUTION SEE MOODLE: MICROBIOLOGY I Wk Date Lecture (Thu 11:40, Pelouch Hall) Presenting Week's practicals (gr.2 Mon 8:00, gr.1 Tue 8:00, gr.3 Wed 11:40, gr.4 Fri 8:00) 1 26.02.2026 Introduction to Medical microbiology, basics of bacterial cell genetics Doc. MVDr. Oto Melter, Ph.D. "Preanalytical phase of microbiological diagnostics " 2 05.03.2026 Bacterial cell. Pathogenicity of bacteria. RNDr. Jan Tkadlec, Ph.D. Microscopy in bacteriology 3 12.03.2026 Introduction to antibiotics. Systematics of antimicrobials I (execpt for betalactams). doc. MVDr. Oto Melter, Ph.D. Bacterial cultures and procedures leading to the identification of bacteria 4 19.03.2026 Molecular microbiology Prof. MUDr. Pavel Dřevínek, Ph.D. SEMINAR: BETALACTAM ABS.Antimicrobials susceptibility testing (AST) 5 26.03.2026 Significant G+ cocci I (staphylococci) RNDr. Jan Tkadlec, Ph.D. Serological methods 6 02.04.2026 G+ cocci II (streptococci and enterococci) - CREDIT TEST I Mgr. Marcela Krůtová, Ph.D. Diagnostics of G+ cocci I (staphylococci) 7 09.04.2026 G+ rods (corynebacteria, listeria, clostridia) Doc. MVDr. Oto Melter, Ph.D. Diagnostics of G+ cocci II (streptococci and enterococci) 8 16.04.2026 G- bacteria I (enterobacteria) w/ G+ and G- anaerobes MUDr. Anežka Gryndlerová Diagnostics of important G+ rods (corynebacteria, listeria, clostridia and bacilli) 9 23.04.2026 G-bacteria II (non-fermenters, Campylobacter, Helicobacter) doc. MVDr. Oto Melter, Ph.D. Diagnostics of G-bacteria I. (enterobacteria) and anaerobes 10 30.04.2026 G- bacteria III (fastidious: Bordetella, Legionella, Haemophilus, Meningcoccus ) MUDr. Daniela Lžičařová Diagnostics of G-bacteria II - nonfermenters, Campylobacter, Helicobacter 11 07.05.2026 Mycology I: general principles, antifungal agents, dermatophytes MUDr. Daniela Lžičařová "Seminar: Brucella, Francisella. Diagnostics of G-bacteria III - fastidious bacteria (bordetella, Legionella, haemophilus, meningococcus) Wednesday: Rector's sport day" 12 14.05.2026 Mycology II: Candidiasis, cryptococcosis, aspergillosis, mucormycosis, Pneumocystis jirovecii pneumonia. MUDr. Daniela Lžičařová Diagnostic methods in mycology // SEMINAR: General parasitology. Basics of malaria and intestinal paraitics diseases. Diagnostic methods in parasitology 13 21.05.2026 General virology. CREDIT TEST 2. MUDr. Petr Hubáček, Ph.D. Diagnostic methods in mycology // SEMINAR: General parasitology. Basics of malaria and intestinal paraitics diseases. Diagnostic methods in parasitology 14 28.05.2026 Consulations. NA PRACTICAL EXAM
Poslední úprava: Hurych Jakub, MUDr., Ph.D. (17.02.2026)
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