The subject provides knowledge about the status of phytopharmaceuticaůs in the current therapy and usability of drugs of this type in the treatment of various pathological conditions. It provides information on the effect of drug substances, standardized extracts that are forming part of such preparations. The course is also focused on the practical use of individual products in the practice of pharmacists. Attention is also paid to possible interactions with chemically unified drugs. The subject assumes knowledge of pharmacognosis, pharmacology, toxicology and pharmaceutical chemistry.
Last update: Šafratová Marcela, PharmDr., Ph.D. (22.07.2024)
Předmět přináší studentům znalosti o postavení fytofarmak v současné terapii a využitelnosti léčiv tohoto typu v léčbě různých patologických stavů. Podává informace o působení obsahových látek léčivých drog, příp. standardizovaných extraktů, tvořících součást takovýchto přípravků. Pozornost je věnována také možným interakcím s chemicky jednotnými léčivy. Předmět předpokládá znalosti z farmakognozie, farmakologie, toxikologie a farmaceutické chemie.
Last update: Šafratová Marcela, PharmDr., Ph.D. (22.07.2024)
Course completion requirements -
the subject is completed by an exam.
Last update: Šafratová Marcela, PharmDr., Ph.D. (22.07.2024)
podmínkou absolvování předmětu je úspěšné složení písemného testu
Last update: Šafratová Marcela, PharmDr., Ph.D. (22.07.2024)
Literature -
Recommended:
Schulz, Volker; Hänsel, Rudolf; Blumenthal, Mark; Tyler, Varro E. Rational Phytotherapy. Berlin, Heidelberg: Springer, 2004, s. ISBN 978-3-642-07406-6.
EVANS, W. C., EVANS, D., & TREASE, G. E.. Trease and Evans' Pharmacognosy. Edinburgh: Saunders/Elsevier, 2009, 612 s. ISBN 0702018996.
James E. Robbers, Marilyn K. Speedie, Varro E. Tyler. Pharmacognosy and Pharmacobiotechnology. : Williams & Wilkins, , 337 s. ISBN 068308500X.
Last update: prepocet_literatura.php (19.09.2024)
Povinná:
. . In Harborne, Jeffrey B.. Phytochemical methods : <<a >>guide to modern techniques of plant analysis . London: Chapman & Hall, 1984, s. -. ISBN 0-412-25550-2..
. . In Kar, Ashutosh. Pharmacognosy and pharmacobiotechnology . Tunbridge Wells: Anshan, 2008, s. -. ISBN ..
Last update: Šafratová Marcela, PharmDr., Ph.D. (22.07.2024)
Learning outcomes
Phytopharmaceuticals course builds on the knowledge and skills acquired in Organic Chemistry I and II, Pharmaceutical Botany I and II, Pharmacognosy I and II, and Pharmacology I and II.
Upon successful completion of the course, students will be able to understand and apply the following terms (including their commonly used abbreviations) in the correct context related to the evaluation and practical use of phytopharmaceuticals: natural-origin medicines, nutraceuticals, medical devices, bioactive compounds, extracts, tinctures, standardization, quality control, regulatory framework, EMA, FDA, SÚKL, EFSA, herbal medicinal products, clinical studies, pharmacovigilance.
Learning Outcomes:
Based on the acquired knowledge and skills, students will be able to:
Define fundamental legislative terms related to phytopharmaceuticals and navigate the applicable legal framework.
Identify key bioactive compounds present in medicinal plants and describe their pharmacological effects.
Distinguish different forms of herbal preparations and explain their significance for therapeutic use.
Critically evaluate scientific information on the efficacy and safety of phytopharmaceuticals, including clinical studies.
Apply principles of standardization, quality control, and pharmacovigilance in the assessment of herbal preparations.
Assess the role of phytopharmaceuticals within conventional medicine.
Last update: Šafratová Marcela, PharmDr., Ph.D. (31.03.2025)