Pathological Physiology I - FDP029

• Title: Pathological Physiology I
• Guaranteed by: Department of Pathological Physiology (15-330)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2021 to 2024
• Semester: winter
• Points: 0
• E-Credits: 4
• Examination process: winter s.:
• Hours per week, examination: winter s.:45/15, C [HS]
• Capacity: unlimited
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Guarantor: prof. MUDr. Zuzana Kubová, CSc.
• Pre-requisite : {Compulsory subjects 1st year Dentistry (2019->)}, FDP016, FDP017, FDP019, FDP020
• Incompatibility : FZ10026
• Interchangeability : FA0205040, FZ10026
• Is co-requisite for: FDP030
• In complex pre-requisite: FDP063, FDP064, FDP065, FDP066, FDP067, FDP068, FDP069, FDP070, FDP071, FDP072, FDP073, FDP074, FDP075, FDP076, FD10059, FD10069, FD10070, FD10071, FD10072, FD10073, FD10074, FD10075, FD10076, FD10078, FD10079, FD10080, FD10081, FD10082

Annotation

Pathophysiology for dentistry students is reduced and includes mainly information related either to particular dentistry problems or to an ability of Dentistry doctors to recognize such diseases in their patients which can be discovered first just by Dentists (when they are not fully clinically manifested), since they have close contacts with their patients. However, similarly like in General Medicine students the first part is devoted to description of general mechanisms of health disorders and their effects on body functions. Problems which accompany a lot of diseases like inflammation, hypoxia, disorders of internal body environment, pain etc. are instructed. Hematological, cardiovascular and respiratory diseases are still included in this first block. In practical classes students are instructed in registration of electrocardiogram and in evaluation of ECG pathological changes, also spirometry is performed, and typical findings are discussed.

Last update: Kořínková Lenka (14.09.2023)

Aim of the course

1.      ability to explain general principles and consequences of impaired body functions

2.      knowledge of pathophysiology of cardiovascular, respiratory and blood diseases

3.      description of basic parameters of ECG and distinguishing pathological from physiological findings

4.      distinguishing normal spirometry recording from findings typical for obstructive and restrictive respiratory disorders

Last update: Kořínková Lenka (14.09.2023)

Literature

Compulsory literature

Kuba, M., Kubová, Z.  Pathophysiology - Basic overview for medical students (revised (only electronic) version)

Last update: Kořínková Lenka (14.09.2023)

Requirements to the exam

Credit:

a) presence in practical classes/seminars

-         mandatory 100% participation

-         in case of absence it is necessary to replace the seminar/practical class (the way of a replacement is determined by the teacher of the particular seminar/practical class, usually it is oral examination of the issue)

 

b) tests

description of two ECG curves when each must be evaluated with the worst grade 3 (in the range 1(excellent) – 4 (fail))

passing all the ongoing tests with the worst grade 3

-         in case of non-participation, an apology before the time of the test is required and the test must be taken on an alternative date

-         student is allowed to one excuse during the whole year

-         non-excused absence is evaluated wit grade 4

Possibility of consultations after previous agreement with teachers of Department of pathological physiology 

Last update: Kořínková Lenka (14.09.2023)

Syllabus

Lectures

Lecturers

• prof. MUDr. Miroslav Kuba, DSc.
• prof. MUDr. Zuzana Kubová, CSc.
• MUDr. Marie Chutná
• MUDr. Lenka Miščík Ramešová

Lectures

1.      Organism and Environment. Health versus Disease. Etiology and Pathogenesis. (Kuba)

2.      Inflammation. SIRS. Pathophysiology of thermoregulation. Fever. (Chutná)

3.      Hypersensitivity reactions. Allergies. Mechanism of Autoimmune disease. Immunodeficiency. (Chutná)

4.      Stress. Psychosomatic Diseases. (Kuba) 

5.      Disorders of Calcium and Phosphorus metabolism. Osteoporosis, osteomalacia. Renal osteodystrophy. (Kuba)

6.      Hypokalemia. Hyperkalemia. Acidosis. Alkalosis. (Chutná) TEST - disorders of calcium metabolism (Kuba)

7.      Alterations in Fluid Volume. Hyponatremia. Hypernatremia. Etiology and Pathogenesis of Oedema. (Kubová)

8.      Arteriosclerosis, Arterial Hypertension. (Kubová)

9.      Ischemic heart disease. Heart failure - compensatory mechanisms. (Kuba)

10.    Arterial Hypotension. Circulatory shock. Syncope. Collapse. (Chutná)

11.    Ventilatory and circulatory lung dysfunctions. Respiratory failure, ARDS. Hypoxia. (Kubová)

12.    Nausea. Vomiting. Gastric Ulcer. Duodenal Ulcer. Gastritis. (Miščík Ramešová)

13.    Disorders of hemostasis. Bone Marrow Depression. (Kuba)

14.    Cirrhosis of the Liver. Hepatic Failure, Hepatic Coma. Jaundices. Pancreatitis. Cholelithiasis. (Kuba)

15.    Diarrhoea. Constipation. Irritable Bowel Syndrome. Inflammatory Bowel Disease. Intestinal obstruction (Ileus). (Miščík Ramešová)

Practical courses & seminars

Teachers

• prof. MUDr. Zuzana Kubová, CSc.
• prof. MUDr. Miroslav Kuba, CSc.
• MUDr. Jana Langrová, Ph.D.
• MUDr. Jana Szanyi, Ph.D.

Seminars

1.      Pathophysiology of Anemias. 

 

Practical courses

1.      ECG - description I. 

2.      ECG - description II.

3.      ECG - practice. TEST - ECG. (Langrová)

4.      Spirometry (computer recording and evaluation). TEST - haemostatsis disorders. (Kuba)

Last update: Kořínková Lenka (15.09.2023)

Entry requirements

prerequisites – compulsory subjects of 1^st year Dentistry, Biochemistry II, Physiology II. 

Last update: Kořínková Lenka (14.09.2023)