Molecular Medicine - FDP064

• Title: Molecular Medicine
• Guaranteed by: Department of Medical Biology and Genetics (15-120)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2025
• Semester: winter
• Points: 0
• E-Credits: 1
• Examination process: winter s.:
• Hours per week, examination: winter s.:9/3, C [HS]
• Capacity: unlimited
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Guarantor: doc. RNDr. Věra Králová, Ph.D.
• Pre-requisite : {Compulsory subjects 3rd year Dentistry (2019->)}
• Incompatibility : FZ10065
• Interchangeability : FA0209137
• In complex pre-requisite: FDP079

Annotation

Genomics in medicine – human genome, methods of gene mapping, genomics, transcriptomics, proteomics, translation of genomic data into clinical practice. Gene therapy – theoretical concepts, current clinical applications. Non-coding RNAs – functions, emerging medical significance. Biological therapy of tumours. Epigenetic mechanisms in the control of gene expression.

Last update: Laláková Marcela (08.09.2025)

Literature

Recommend literature

1. J. Pongracz, M. Keen Medical Biotechnology, Elsevier, 2009, ISBN 978-0-08-045135-0
2. Internet - based on-line databases Medline and PubMed

Last update: Laláková Marcela (08.09.2025)

Requirements to the exam

REQUIREMENTS FOR CREDIT:

For credit, student should attend the lectures and practical class and pass a credit test.

Last update: Laláková Marcela (11.09.2025)

Syllabus

Practical courses & seminars

Lecturers:

• Doc.RNDr. Vera Kralova, Ph.D.
• Prof. PharmDr. Emil Rudolf, Ph.D.
• RNDr. Jana Nekvindová, Ph.D.

Seminars:

• Genomics and the search for genes responsible for diseases.
  Gene therapy
  Genetic heterogeneity of tumors – e-learning.
• Clinical applications of molecular genetic methods

Practical class:

• Clinical applications of molecular genetic methods – molecular genetic laboratories of the Derpartment of Clinical Biochemistry and Diagnostics, University Hospital

Last update: Laláková Marcela (11.09.2025)