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Course, academic year 2023/2024
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Hygiene and Epidemiology - B83151 (Dentistry)
Title: Hygiene and Epidemiology
Guaranteed by: Institute of Hygiene and Epidemiology First Faculty of Medicine Charles University and General University Hospital in Prague (11-00200)
Faculty: First Faculty of Medicine
Actual: from 2023
Semester: winter
Points: 2
E-Credits: 2
Examination process: winter s.:
Hours per week, examination: winter s.:14/28, C+Ex [HS]
Extent per academic year: 42 [hours]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Guarantor: prof. MUDr. Milan Tuček, CSc.
Comes under: Compulsory for Dentistry 3.y._23/24
Attributes: Teoretický předmět
Zubní lékařství
Pre-requisite : B81148, B83113
Interchangeability : B81155
Syllabus
Last update: Jana Kolářová (28.01.2020)
HYGIENE

Hygienic issues in health services Occupational hygiene and occupational health (OH): focus, history and legislation. Basic definitions -exposure, hazard, risk, risk assessment. Exposure assessment - principle of occupational risk assessment. Risk analysis at work. Hazard identification. Occupational risk assessment and management, practical examples (dentistry). Principles of medical fitness assessment.

Physical factors of environment

Noise, vibrations, non-ionising radiation, lighting, UV radiation, ionising radiation, climatic factors.

Health and environment

Basic terms and definitions of hygiene and epidemiology; notes on history, primary prevention, adaptation, acclimatization, induction of tolerance, vaccination, health promotion. Secondary and tertiary prevention - forms, objectives, practice. Men and environment versus importance of lifestyle for human health. Local & global problems caused by persistent xenobiotics like toxic metals, polyhaloganated hydrocarbons and ionizing radiation. Energy production and traffic emissions. Biological monitoring, biological exposure test, biological limit.

Water

Water and health: physiological importance, water metabolism, requirements on the quality of drinking water and related health hazards. Drinking water treatment, fluoridation, disinfection, ozone, UV radiation, filters. Preparation of drinking water in emergency situations. Self-cleaning capability of surface water, recreational waters and related health risks. Water-born infections. Waste water treatment - principles. Health risks of waste water improper treatment.

Indoor/outdoor pollution, sick building syndrome.

Pollution of indoor environment: Building - related difficulties and their causes, especially allergies and asthma and risk factors for them indoors; Non-specific disorders like humidifier fever, hypersensitivity pneumonitis, sick building syndrome, multiple chemical sensitivity syndrome, electrical sensitivity syndrome; Toxic reaction (moulds)

Infectious diseases - viral, bacterial, fungal [real building-related illnesses], Cancer - especially problems with radon in buildings. Known risk factors of these problems, how to prevent disorders cause by the pollution of indoor environment and how to treat either a building (elimination of some equipment), or the patient.

Outdoor factors and pollution: Chemical factors - inorganic compounds (NOx, SO2, CO, CO2) ozone; organic compounds (VOCs, formaldehyde, PAHs); outdoor pollution in students’countries - health hazards and possible ways, how to solve these problems.

Lifestyle - nutrition

Dietary guidelines for population. Food composition, significance of specific nutrients and food groups. Infant & young child nutrition. Food safety. Malnutrition.

Lifestyle - tobacco dependence

The tobacco epidemic; tobacco related morbidity and mortality, health impact of tobacco use, different forms of tobacco use, tobacco smoke composition, passive smoking. Effecetive prevention measures, basics of tobacco dependence (psychobehavioural and physical/drug dependence), basic treatment recommendations for any health professionals, possibilities in the Czech Republic and worldwide, international recommendations.

EPIDEMIOLOGY

Epidemiological method of work

Descriptive studies; the basic characteristics of person, place and time. Analytical studies - cohort studies, case-control studies. Advantages and disadvantages, examples. Experimental studies - ethical problems of experiment. Clinical control study, field control study. Method of blind experiment. Natural experiments. Risk, incidence density, population time (person-years). Associations in analytical studies: risk difference, risk ratio, rate ratio, odds ratio.

Statistics

Introduction of statistical methodology. Descriptive and inductive statistics, statistical induction. Types of random samples. Quantitative and qualitative variables. Measures of location and variability. Gaussian distribution. Planning of epidemiological studies. Principles of statistical hypotheses testing. Evaluation of epidemiological studies. Tests of hypotheses in four-fold table. Contingency table and Chi-square distribution. General principles of measuring statistical dependence.

Process of infection spreading

Characteristics. Elimination, eradication. Etiological agents - pathogenicity, virulence, toxicity, invasiveness, resistance, infectious dose. Links of the process of infection spreading: source of infection, transmission, susceptible individual.

Epidemiology of infectious diseases.

Importance of infectious disease in history and now. Global incidence. Food-borne infection; Air-borne infection; Contact infections of the skin and mucous membranes. Vector-born infection; Diseases transmitted by blood. Occurrence, etiology, sources, ways of spreading. Prevention and repression. Nosocomial infections - Specific & non-specific; exogenous and endogenous Risk factors. Occurrence, etiology, sources, ways of spreading. Prevention and repression.

Anti-epidemic measures; immunization

Preventive and repressive anti-epidemic measures. Disinfection, sterilization. (Sterilization - physical, chemical methods and control. Disinfection - physical, chemical methods. Immunization: importance, Herd immunity. Immunization programmes. Types of vaccines, requirement, contraindications. Organization of vaccination.

Epidemiology of malignant tumours

Incidence & mortality of cancer in different part of the world, special sites of cancer important in different parts of the world; potential risk factors - non-susceptible/susceptible: chronic infections, smoking, diet; IARC classification of carcinogens, some examples of classified carcinogens.

Epidemiology of cardiovascular diseases (CVD). Epidemiology, comparison with other countries, trends, different kinds of CVD. Atherosclerosis and its genesis, different stages, clinical manifestation. Risk factors of CVD - controllable (life-style factors - alcohol and tobacco consumption, diet, physical activity etc.), uncontrollable (age, gender, family history etc.). Basic information about metabolic syndrome, diabetes, obesity and hyperlipidaemia. SCORE chart for evaluation of CVD risk - hyperlipidaemia, hypertension, age and tobacco consumption. Stress and its sense - acute, chronic, chronic fatigue syndrome, burn-out syndrome.

Literature - Czech
Last update: Jana Kolářová (28.01.2020)

Povinná:

  • Bencko, Vladimír. Hygiene and epidemiology : selected chapters. Praha: Karolinum Press, 2019, 236 s. ISBN 978-80-246-4313-7.
  • Bonita, R., Beaglehole, R., Kjellstrom, T. Basic Epidemiology. Geneva: WHO, 2nd Edition , 2006, 226 s. ISBN 978 92 4 154707 9.
  • LaDou, J. Harrison, R. Current Occupational and Environmental Medicine. New York: McGraw-Hill Education, 5 edition, 2014, 864 s. ISBN 978-0071808156.
  • Palmer K.T., Brown I.,Hobson J. Fitness for Work. : Oxford University Press, 5 edition, 2014, 736 s. ISBN 978-0199643240.
  • Dietary Reference Values for nutrients Summary report [online]. Dostupné z: https://www.efsa.europa.eu/sites/default/files/2017_09_DRVs_summary_report.pdf
  • Presentations of the Institute of Hygiene and Epidemiology [online]. Dostupné z: http://hyg.lf1.cuni.cz/en/

 
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