Immunology - DA0105044

• Anglický název: Immunology
• Zajišťuje: Ústav imunologie (13-722)
• Fakulta: 2. lékařská fakulta
• Platnost: od 2021
• Semestr: zimní
• Body: 6
• E-Kredity: 6
• Způsob provedení zkoušky: zimní s.:
• Rozsah, examinace: zimní s.:2/2, Z+Zk [HT]
• Rozsah za akademický rok: 14 [týdny]
• Počet míst: neomezen / neomezen (neurčen)
• Minimální obsazenost: neomezen
• 4EU+: ne
• Virtuální mobilita / počet míst pro virtuální mobilitu: ne
• Stav předmětu: vyučován
• Jazyk výuky: angličtina
• Způsob výuky: prezenční
• Způsob výuky: prezenční
• Garant: prof. MUDr. Jiřina Bartůňková, DrSc.
• Kategorizace předmětu: Lékařství > Teoretické předměty
• Prerekvizity : DA0103337
• Je prerekvizitou pro: DA0108369

Anotace

Poslední úprava: HABET (02.11.2012)

Courses in Basic Immunology and Immunopatology

Podmínky zakončení předmětu

Poslední úprava: Irena Nováková (08.09.2017)

Oral examination: 2 out of 50 questions

Literatura

Poslední úprava: Irena Nováková (08.09.2017)

Abbas, A. K.: Cellular and molecular immunology : Elsevier, 2012 (B) (2015 - available as ebook)

Murphy, K. M.: Janeway’s immunobiology. Garland science, 2012 (B)

Paul, W. E: Fundamental immunology. Lippincott Williams & Wilkins, 2013.7th ed.

Rich, R. R.: Clinical immunology : principles and practice. Elsevier Saunders, 2013. 4th ed.

Požadavky ke zkoušce

Poslední úprava: Irena Nováková (08.09.2017)

Exam Questions

1.Central and peripheral lymphoid organs

2.The origine and differentiation of immunocompetent cells

3.Nonspecific immunity

4.Specific immunity

5.Humoral immunity

6.Cellular immunity

7.Nonimmunological defense mechanisms

8.Monocyte-macrophages

9.Granulocytes, types and function

10.Phagocytosis

11.Killing mechanisms of phagocytic cells, cytotoxic T lymphocytes and NK cells

12.Complement and its function

13.NK cells, surface molecules, function

14.Cytokines and their role in immune reaction

15.Antigen processing and presentation

16.HLA class I, structure, function

17.HLA class II, structure, function

18.Lymphocytes T, differentiation, subpopulations

19.Membrane molecules of T-lymphocytes and their function

20.Lymphocytes TH1

21.Lymphocytes TH2

22.Lymphocytes B, developement and differentiation

23.Imunoglobulins G and M, structure and function

24.Imunoglobulin A, structure and function

25.Imunoglobulin E, structure and function

26.Primary and secondary antibody response

27.Mucosal immunity

28.Immune mechanisms in defense against parasites

29.Immune mechanisms in defense against bacterial infections

30.Immune mechanisms in defense against viral infections

31.Immune mechanisms in defense against tumors

32.Immunopatological reaction type I-anaphylactic

33.Immunopatological reaction type II-cytotoxic

34.Immunopatological reaction mediated by immune complexes

35.Immunopatological reaction mediated by T-lymphocytes

36.Pathogenesis of the septic shock

37.Mechanism of action of antireceptor antibodies

38.Immunological reactions involved in transplant rejection

39.Graft versus host reaction

40.The causes of autoimmune diseases

41.Mechanisms of central and peripheral tolerance

42.Organ based autoimmune diseases

43.Systemic autoimmune diseases

44.Antibody deficiencies

45.Combine immunodeficiencies

46.Immune deficiency induced by HIV infection

47.Aquired disorders of immunity

48.Possibilities of suppression of immune response

49.Possibilities of stimulation of immune response

50.Vaccination

Sylabus

Poslední úprava: Irena Nováková (08.09.2017)

Immune system, overview. Phagocytic cells, complement. Communication between cells of immune systems, adhesion molecules, cytokines.

Antigen processing and presentation, HLA I and II class.

Specific (adaptive) immunity T and B lymphocytes

Immunity against infection

Immunodeficiency,vaccination

Immunity against tumors.

Immunology of transplantation.

Autoimmunity.Immunopathology.

Immunopathological reactions, allergy.

Immunotherapy

Clinical aspects of immune disorders