PředmětyPředměty(verze: 945)
Předmět, akademický rok 2016/2017
   Přihlásit přes CAS
Onkologie - B80120
Anglický název: Clinical Oncology
Zajišťuje: Onkologická klinika 1. LF UK a VFN (11-00630)
Fakulta: 1. lékařská fakulta
Platnost: od 2014 do 2016
Semestr: zimní
Body: 3
E-Kredity: 3
Způsob provedení zkoušky: zimní s.:
Rozsah, examinace: zimní s.:0/50, Z+Zk [HS]
Rozsah za akademický rok: 50 [hodiny]
Počet míst: neomezen
Minimální obsazenost: neomezen
4EU+: ne
Virtuální mobilita / počet míst pro virtuální mobilitu: ne
Stav předmětu: vyučován
Jazyk výuky: angličtina
Způsob výuky: prezenční
Způsob výuky: prezenční
Vysvětlení: MUDr. Martin Matějů, Ph.D.
Staré označení: 764
Garant: prof. MUDr. Luboš Petruželka, CSc.
Atributy: Lékařství
Klinický předmět
Prerekvizity : B80384, B80385, B80386, B80632
Literatura - angličtina
Poslední úprava: MUDr. Martin Matějů, Ph.D. (27.09.2023)

Recommended:

  • DeVita, Vincent T., Lawrence, Theodore S. Rosenberg, Steven A. (eds.). Cancer, Principles and Practice of Oncology. Philadelphia: Wolters Kluwer, 2019, 2390 s. ISBN .
  • Abraham, Jame, Gulley, James L.. Bethesda Handbook of Clinical Oncology. : Lippincott Williams and Wilkins, 2020, s. ISBN .
  • Cassidy J.. Oxford Handbook of Oncology. : Oxford University Press, 2015, s. ISBN .
  • UpToDate, accessible via Institute of Scientific Information,1st Faculty of Medicine [online]. Dostupné z: https://www.uptodate.com
  • NCCN guidelines [online]. Dostupné z: https://www.nccn.org/professionals/physician_gls/default.aspx

Vstupní požadavky - angličtina
Poslední úprava: MUDr. Martin Matějů, Ph.D. (22.09.2020)

Lessons will start on Monday at 9 a.m. at Všeobecná fakultní nemocnice v Praze (VFN) - Fakultní Poliklinika, Karlovo náměstí 32, Praha 2 - lecture hall in bulding A, gound floor, central part - on righthand side, door no.: P.21 where students will be provided with futher information about the schedule, gainning of the credit and the exam.

Detailed time table  contating lesson´s topics, meeting points and instructions how to get to other departments is available at: https://1url.cz/ZMD1F / please notice also the "webs and adresses" sheet/.

Places and meeting times for visiting other departments  (for more details please see the shared doc. above):

- lessons assigned to VFN - apart of the first meeting, start at 8 a.m. Monday and Friday also at Fakultní Poliklinika, Karlovo náměstí 32, Praha 2 - lecture hall in bulding A, gound floor, central part - on righthand side, door no.: P.21 and on Thursday (study group performing the Grand Round) - seminary chamber at Oncology Ward (beside Oncology secretariat), building A6, 1. floor - please use stairway on the lefthand side of the hallway (beside Oncology secretariat

- lessons assigned to Ústav radiační onkologie (ÚRO) Nemocnice Na Bulovce, Na Truhlářce 100,Praha 8 - students will gather at 9 a.m. in  building  B, 1. floor - conference corner at  estibul, to be pick-up by the lecturer 

- lessons assigned to Onkologická klinika Ústřední vojenská nemocnice (ÚVN), U Vojenské nemocnice 1200, Praha 6 - students should meet at 8:30 a.m., building A1 - middle, 1. floor, Oncology department 

- lessons assigned to Onkologická  klinika Thomayerovy nemocnice (TN), Vídeňská 800,  Praha 4 - students should meet at 9 a.m.  at building A, gropund floor, seminary chamber of Oncology clinic

lessons assigned to Nemocnici Na Pleši: students will be fully informed on first day of the course

 

* Students will gain credit when fullfilling attendance sheet and passing the exam.

* Exam "pre-dates" ( maily in 2 weeks following the course) will be given on last Friday in total count equal to number of studets (with Erasmus) gaining the credit. If a student miss this "pre-date" it is not possible to sign up to "pre-dates" of other study groups and the exam must be taken in  regular exam date at the end of semester. 

Head od education at Oncology Clinic: MUDr. Martin Matějů, PhD.; contact:  matejum@post.cz 

Požadavky ke zkoušce - angličtina
Poslední úprava: MUDr. Martin Matějů, Ph.D. (26.06.2019)
Questions for final exam:
 
a/ Principles of oncology: 
 
1. Primary and secondary prevention, screening in oncology - definition, theory of successful screening, screening in the clinical practice
2. Tumour epidemiology - descriptive and analytical epidemiology, regional differences in cancer incidence and mortality, epidemiological studies, hereditary cancer syndromes
3. Biology of cancer growth - overview of carcinogenesis, radiation, chemical and viral carcinogenesis, cell cycle and its dysregulation in cancer, biology of metastasis.
4. Molecular biology in oncology - oncogenes, tumour-suppressor genes, oncoproteins, gene therapy
5. Medical history and physical examination in oncology - specific aspects, symptoms and signs of malignancies, hereditary cancer syndromes
6. Diagnostic imaging in oncology - X-ray, ultrasound, computer tomography, magnetic resonance
7. Nuclear medicine in oncology - scintigraphy, SPECT, PET
8. Tumour verification - histopathology, cytology, biopsy
9. Haematological and biochemical analysis in oncology - whole blood count, biochemistry, serum tumour markers, functional tests
10. Staging - principles of staging, TNM system
11. General principles of cancer treatment - therapeutic intent, survival, curative and palliative approaches, symptom management in advanced cancer
12. Principles of surgical treatment in oncology - therapeutic intent, surgery as part of multimodal therapy, curative and palliative procedures, cytoreductive surgery
13. Principles of radiotherapy - basic overview of radiobiology, sources of radiation, delivery of therapeutic radiation, radiotherapy planning, adverse effect
14. Principles of chemotherapy - basic overview of chemotherapy, curative and palliative chemotherapy, adjuvant chemotherapy, dose intensity, types of chemotherapy drugs
15. Adverse effects of chemotherapy - local and systemic adverse effects, organ toxicity, febrile neutropenia, nausea and vomiting, late effects, treatment of adverse effects
16. Hormonal therapy - hormonally dependent cancers, prediction of hormonal dependence, hormonal receptors, hormonal therapy in clinical use, types of hormonal therapy
17. Targeted cancer therapy - molecular targets, adverse effects, combinations with chemotherapy, current role in cancer treatment
18. Immunotherapy - molecular targets, adverse effects, current role in cancer treatment
19. Supportive treatment - supportive treatment in oncologic surgery, radiotherapy, and chemotherapy, febrile neutropenia, leukocyte growth factors, vomiting, psychotherapy in oncology
20. Pain in patients with cancer - acute and chronic pain, pharmacotherapy of pain, pain surgery
21. Tumour response assessment - staging, restaging, follow-up, RECIST criteria
22. Performance status, quality of life - nutrition, cachexia, systemic signs and symptoms of malignancy
23. Terminal care - symptom management in advanced cancer, social care, hospice care, role of family members
24. Rehabilitation in oncology - physical, social, and psychological rehabilitation
25. Psychooncology - communicating the diagnosis of cancer, short-term and long-term psychological consequences of cancer
26. Follow-up of cancer patients - overview and purpose of follow-up care, relapse, minimal residual disease, evaluation of treatment results
27. Oncologic emergencies - febrile neutropenia, bleeding, obstruction syndromes, thromboembolic complications, effusions, electrolyte disorders
spinal compression, intracranial  hypertension, hypercalcemia
 
b/ Practice of oncology - answer structure a)epidemiology and risk factors, b) signs and symptoms, c) diagnosis and clinical staging , d) treatment overview:
 
1. Head and neck cancers
2. Thyroid cancer
3. Malignant tumours of unknown origin
4. Malignancies of the mediastinum
5. Malignancies of the lung and pleura
6. Oesophageal cancer, gastric cancer,  gastroesophageal junction cancer
7. Colorectal cancer
8. Primary liver cancer and cancer metastatic to the liver
9. Urinary bladder cancer
10. Renal cancer and upper urinary tract cancers
11. Pancreatic cancer, biliary cancer
12. Prostate cancer
13. Testicular tumours
14. Ovarian cancer and trophoblastic malignancies
15. Cancers of the uterine cervix and body
16. Childhood malignancies
17. Endocrine malignancies (except thyroid cancer)
18. Breast cancer
19. Melanoma, basalioma and cutaneous squamous cell cancer
20. Soft tissue and bone sarcomas
21. Acute and chronic leukaemias, haematopoietic stem cell transplantation
22. Hodgkin and non-Hodgkin lymphomas
23. Central nervous system malignancies (primary tumours and metastases)
 
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