Introduction to Chemistry - FV035

• Title: Introduction to Chemistry
• Guaranteed by: Department of Medical Biochemistry (15-180)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2023
• Semester: summer
• Points: 0
• E-Credits: 2
• Examination process: summer s.:
• Number of self-study hours: 18 [hours/semester]
• Hours per week, examination: summer s.:0/12, C [HS]
• Capacity: 36
• Min. number of students: 5
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Note: course can be enrolled in outside the study plan; enabled for web enrollment
• Guarantor: Mgr. Alena Mrkvicová, Ph.D.
• Comes under: Dentistry - ELECTIVE subjects; Dentistry - ELECTIVE subjects (2019->; General medicine - ELECTIVE subjects
• Incompatibility : FDP016, FD10016, FGP013, FG10013, FG50014
• Interchangeability : FG50014

Annotation

Last update: doc. MUDr. Alena Stoklasová, CSc. (02.02.2024)

The aim of this subject is to review briefly high school knowledge of chemistry including the nomenclature of inorganic and organic compounds, basic stoichiometric calculations, pH , basic reactions in organic chemistry with the attention paid to the structures and reactions important in biochemistry.

Requirements to the exam

Last update: doc. MUDr. Alena Stoklasová, CSc. (02.02.2024)

Credit:

Completion of the e-learning course and attendance at seminars

Credit test: focused on nomenclature of inorganic and organic compounds (including trivial nomenclature), basic calculations, balancing of chemical reactions, organic compounds, basic reactions in organic chemistry.

Syllabus

Last update: doc. MUDr. Alena Stoklasová, CSc. (02.02.2024)

Lectures

1.       Periodic system - a theoretical introduction: periodic law and the laws arising from it, electronegativity. Atomic structure (atomic masses, isotopes). Nomenclature of inorganic compounds. (2h)

2.       Chemical reactions - classification according to various criteria. Bonds in molecules - covalent, ionic, metal binding and coordination. Non-binding interactions - dipole interactions, hydrophobic interactions, hydrogen bonds. Energetics of chemical reactions - internal energy, enthalpy, free enthalpy, entropy, thermodynamic laws. (2h)

3.       Kinetics of chemical reactions - speed and reaction order, Guldberg-Waage law, theory of activated complex, catalysis. Equilibrium states. (1h)

4.       Oxidation and reduction - oxidoreduction state, oxidoreduction reaction, oxidoreduction potential. (1h)

5.       Electrolytes and dissociation - strong and weak electrolytes, degree of dissociation and dissociation constant. Acids and bases - theory, pH. (2h)

6.       Chemical calculations: stoichiometrical calculations, concentration, dilution, pH. (2h)

7.       Introduction to organic chemistry. IUPAC nomenclature. Isomerism. Hydrocarbons. Substitutional derivatives of hydrocarbons – sulphur and nitrogen containing compounds. (2h)

8.       Oxygen containing organic compounds – alcohols, phenols, aldehydes, ketones, carboxylic acids and their functional and substitutional derivatives. (2h)

9.       Carbohydrates – monosaccharides, cyclic and hemiketal structures.  Oligo- and polysaccharides. (1h)

10.     Lipids – fatty acids, triacylglycerols, chemical reactions, biological functions. (1h)

11.     Proteins – structure, conformation, biological function. Enzymes – classification, structure, mechanism of action.  (2h)

 

Lecturers

• Prof. Martina Řezáčová, M.D., Ph.D.
• Assoc. Prof. Radim Havelek, Dr, Ph.D.
• Assoc. Prof. Miloš Hroch, Ing., Ph.D.
• Assoc. Prof. Alena Stoklasová, M.D., Ph.D.
• Renata Köhlerová, MS, Ph.D.
• Alena Mrkvicová, MS, Ph.D..
• Darina Muthná, Dr., Ph.D.
• Eva Peterová, MS, Ph.D.
• Darja Koutová, MS, Ph.D.
• Martin Uher, Dr.,Ph.D.

Seminars

1.       Practicing of inorganic nomenclature. Stoichiometry of the reaction. (3h)

2.       Practicing chemical calculations. (3h)

3.       Practicing of organic nomenclature and basic reactions in organic chemistry. (3h)

4.       Overview of biomolecules. Credit test. (3h)

Literature

Last update: doc. MUDr. Alena Stoklasová, CSc. (02.02.2024)

Recommended literature:

1. Z. Orszaghova, I. Zitnanova et al.: Medical Chemistry, Univerzita Komenskeho v Bratislave, 2008, ISBN978-80-223-2426-7
2. Z. Durackova et al.: Medical Chemistry. Asklepios, Bratislava, 1993. ISBN 80-7167-003-0