SubjectsSubjects(version: 944)
Course, academic year 2023/2024
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Pharmaceutical Technology II - GF346
Title: Farmaceutická technologie II
Guaranteed by: Department of Pharmaceutical Technology (16-16210)
Faculty: Faculty of Pharmacy in Hradec Králové
Actual: from 2021
Semester: winter
Points: 0
E-Credits: 12
Examination process: winter s.:oral
Hours per week, examination: winter s.:56/70, C+Ex [HS]
Capacity: unlimited / 180 (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: deregister from the exam date if a requisite was not fulfilled
Guarantor: doc. PharmDr. Zdeňka Šklubalová, Ph.D.
Comes under: 4.ročník 2023/24-Farmacie
Pre-requisite : GF344
Interchangeability : GF188
Is co-requisite for: GF327, GF352, GF251, GF320, GF379, GF318, GF378, GF505
Is pre-requisite for: GF363
Annotation -
Last update: doc. PharmDr. Zdeňka Šklubalová, Ph.D. (04.12.2021)
Pharmaceutical technology 2 is focused on specific dosage forms mainly produced in pharmaceutical industry, such as sterile dosage forms, aerodispersion, vaccines, solid dosage forms - tablets, capsules, pellets, etc.). Drug delivery systems with modified release are included. The practical training continues in the evaluation of properties of pharmaceutical products. Seminars improve knowledge of specific methods used in the formulation and/or the evaluation of pharmaceutical preparations.
Course completion requirements -
Last update: doc. PharmDr. Zdeňka Šklubalová, Ph.D. (04.12.2021)

For the credit:


  • practical training and seminars - 100% presence
  • reports from practical training
  • 75% correct in tests

The subject is concluded by passing the exam and it is included in the Final State Examination.


Literature -
Last update: doc. PharmDr. Zdeňka Šklubalová, Ph.D. (04.12.2021)


  • . . In Akers, Michael J.. Sterile drug products : formulation, packaging, manufacturing, and quality . New York: Informa Healthcare, 2010, s. -. ISBN 978-084933993-6..
  • . . In Šklubalová, Zdeňka. Základní praktická cvičení z farmaceutické technologie . Praha: Univerzita Karlova, Nakladatelství Karolinum, 2020, s. -. ISBN 978-80-246-4561-2..
  • . . In Šklubalová, Zdeňka Vraníková, Barbora. Oční přípravky : (Ocularia, Ophthalmica . Praha: Maxdorf, 2018, s. -. ISBN 978-80-7345-572-9..
  • . . In Swarbrick, James, (ed.). Encyclopedia of pharmaceutical technology . New York: Informa Healthcare, 2007, s. -. ISBN 0-8493-9399-X..
  • . . In Mužíková, Jitka. Speciální praktická cvičení z farmaceutické technologie . Praha: Karolinum, 2019, s. -. ISBN 978-80-246-4275-8..

Syllabus -
Last update: doc. PharmDr. Zdeňka Šklubalová, Ph.D. (04.12.2021)

1) Dosage Forms

  • Dosage forms and their classification

  • Pharmaceutical excipients

  • Biopharmaceutical principles in dosage forms

  • Pharmaceutical dispersion systems

  • Liquid dosage forms

  • Semisolid dosage forms

  • Solid dosage forms

  • Sterile dosage forms

  • Inhalation preparations

  • Modified release drug delivery systems

  • Targeted drug delivery systems

    2) Manufacturing operations in pharmaceutical technology

  • Water production

  • Filtration

  • Comminution. Milling

  • Mixing. Homogenization

  • Drying, Freeze Drying

  • Sterilization

    3) Quality control and stability of dosage forms

  • Good manufacturing practice

  • Stability of dosage forms.

  • Pharmaceutical packaging

  • Uniformity of dose

  • Disolution tests

  • Granulometry

  • Rheology

Learning resources -
Last update: doc. PharmDr. Zdeňka Šklubalová, Ph.D. (04.12.2021)

Web FaF:

Teaching methods -
Last update: doc. PharmDr. Zdeňka Šklubalová, Ph.D. (04.12.2021)



practical training

Requirements to the exam -
Last update: doc. PharmDr. Zdeňka Šklubalová, Ph.D. (04.12.2021)

The confirmation of  credits from SIS

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