Viz náplň práce v anglickém jazyce. Kontakt: doc. RNDR. Karolina Schwarzová, Ph.D., email karolina.schwarzova@natur.cuni.cz, místnost Hlavova 8, 114a
Předběžná náplň práce v anglickém jazyce
Sp3 (diamond) carbon-based materials hold an eminent position in electrochemistry, a discipline which has a range of applications from laboratory to industrial scale and from analytical science to energy storage. Typically, their conductivity is achieved by incorporation of boron atoms in the diamond lattice during the chemical vapor deposition (CVD) preparation procedure. The advantageous properties of boron doped diamond (BDD) include biocompatibility, wide potential window, low background current, low proclivity to adsorption, thus this material represents a suitable platform for biosensors construction. For this purpose, surface structuring or modification is required for the successful attachment of biomolecules. The objectives of the project include intentional structuring of BDD surfaces (e.g., using ultra-fast laser technologies) or modification of the surface (introduction of oxygen-containing groups, electrochemical grafting for efficient attachment of organic molecules bearing (-NH2, -COOH groups)) suitable for binding of biomolecules such as proteins or DNA, thus allowing biosensor development. Within this context, complex physico-chemical characterization of the parent and structured/modified BDD surfaces using spectroscopic, microscopic and electrochemical techniques will be performed to study the interplay between the surface and bulk properties of BDD, and electrochemical performance. The project will be solved in close cooperation with Institute of Physics (MNB research group (Dr. Andrew Taylor)) providing BDD thin films. Relevant publications of the project leader and others [1] S. Baluchová, A. Daňhel, H. Dejmková, V. Ostatná, M. Fojta, K. Schwarzová-Pecková, Recent progress in the applications of boron doped diamond electrodes in electroanalysis of organic compounds and biomolecules – A review, Anal. Chim. Acta, 1077 (2019) 30-66. [2] N.J. Yang, S.Y. Yu, J.V. Macpherson, Y. Einaga, H.Y. Zhao, G.H. Zhao, G.M. Swain, X. Jiang, Conductive diamond: synthesis, properties, and electrochemical applications, Chemical Society Reviews, 48 (2019) 157-204. [3] V. Hrdlicka, O. Matvieiev, T. Navrátil, R. Selesovská, Recent advances in modified boron-doped diamond electrodes: A review, Electrochim. Acta, 456 (2023) 142435.
