The bachelor thesis aims to combine literature review with experimental work to describe current knowledge on localization of one type of postranslational modifications – phosporylation on 3D structure of protein. The student will identify relevant literature that maps phosporylation sites on experimentally known 3D structures of proteins or predicts its localization with respect to ordered and disordered regions of proteins. Student will also take advantage of recently predicted 3D structures of proteins for a complete proteome of human to map all the known phosphorylation sites in human of predicted Alphafold structures in the experimental part of the work. Student will also discuss the similarites or differences between the literature knowledge and the results of the experimental part.