Syndrom fixované míchy

• Název práce v češtině: Syndrom fixované míchy
• Název v anglickém jazyce: Tethered cord syndrome
• Klíčová slova: syndrom fixované míchy, filum terminale, paréza, fyzioterapie, trakce, Zebris FDM Tredmill system
• Klíčová slova anglicky: tethered cord syndrome, filum terminale, paresis, physiotherapy, traction, Zebris FDM Tredmill system
• Akademický rok vypsání: 2021/2022
• Typ práce: bakalářská práce
• Jazyk práce: čeština
• Ústav: Klinika rehabilitace a tělovýchovného lékařství (13-432)
• Vedoucí / školitel: PhDr. Petr Bitnar, Ph.D.
• Řešitel: Bc. Anežka Pešicová - zadáno a potvrzeno stud. odd.
• Datum přihlášení: 30.11.2021
• Datum zadání: 09.05.2023
• Datum potvrzení stud. oddělením: 09.05.2023
• Datum a čas obhajoby: 04.09.2023 09:20
• Datum odevzdání elektronické podoby: 13.08.2023
• Datum odevzdání tištěné podoby: 15.08.2023
• Do kdy má student odevzdat: 15.08.2023
• Datum proběhlé obhajoby: 04.09.2023
• Oponenti: Mgr. Júlia Demeková

Seznam odborné literatury

1. LICHTENSTEIN, Ben W. Spinal dysraphism: spina bifida and myelodysplasia. Archives of Neurology & Psychiatry, 1940, 44.4: 792-810.
2. GARDNER, W. James. Hydrodynamic mechanism of syringomyelia: its relationship to myelocele. Journal of neurology, neurosurgery, and psychiatry, 1965, 28.3: 247.
3. BARRY, Alexander; PATTEN, Bradley M.; STEWART, Bruce H. Possible factors in the development of the Arnold-Chiari malformation. Journal of Neurosurgery, 1957, 14.3: 285-301.
4. HOFFMAN, Harold J.; HENDRICK, Bruce; HUMPHREYS, Robin P. The tethered spinal cord: its protean manifestations, diagnosis and surgical correction. Pediatric Neurosurgery, 1976, 2.3: 145-155.
5. YAMADA, Shokei; ZINKE, David E.; SANDERS, Delmar. Pathophysiology of “tethered cord syndrome”. Journal of neurosurgery, 1981, 54.4: 494-503.
6. PANG, Dachling; WILBERGER, James E. Tethered cord syndrome in adults. Journal of neurosurgery, 1982, 57.1: 32-47.
7. LEW, Sean M.; KOTHBAUER, Karl F. Tethered cord syndrome: an updated review. Pediatric neurosurgery, 2007, 43.3: 236-248.
8. Grey's anatomy. Walt Disney Studios Home Entertainment, 2012, 763-764.
9. TANI, S., et al. Changes in lumbosacral canal length during flexion and extension-- dynamic effect on the elongated spinal cord in the tethered spinal cord. No to Shinkei Brain and Nerve, 1991, 43.12: 1121-1125.
10. YAMADA, Shokei; WON, Daniel J. What is the true tethered cord syndrome?. Child's Nervous System, 2007, 23: 371-375.
11. JINDAL, Anupam; MAHAPATRA, Ashok Kumar; KAMAL, Raj. Spinal dysraphism. The Indian Journal of Pediatrics, 1999, 66: 697-705.
12. O'CONNOR, Kyle P., et al. Surgical treatment of tethered cord syndrome in adults: a systematic review and meta-analysis. World Neurosurgery, 2020, 137: e221-e241.
13. MRC VITAMIN STUDY RESEARCH GROUP, et al. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. The lancet, 1991, 338.8760: 131-137.
14. Neuro Surgery 96: Manual of Neurosurgery. Churchill Livingstone, 1996.
15. HERTZLER, Dean A., et al. Tethered cord syndrome: a review of the literature from embryology to adult presentation. Neurosurgical focus, 2010, 29.1: E1.
16. FRENCH, Barry N. The embryology of spinal dysraphism. Neurosurgery, 1983, 30: 295-340.
17. YAMADA, Shokei. Tethered cord syndrome in adults and children. Neurological research, 2004, 26.7: 717-718.
18. YAMADA, Shokei. Tethered cord syndrome in children and adults. Thieme, 2010.
19. PATNAIK, Ashis; MAHAPATRA, Ashok Kumar. Complex forms of spinal dysraphism. Child's Nervous System, 2013, 29: 1527-1532.
20. HOLMES, Lucy C.; LI, Veetai. Occult spinal dysraphism. Pediatrics in review, 2019, 40.12: 650-652.
21. TUNTURI, Archie R. Elasticity of the spinal cord, pia, and denticulate ligament in the dog. Journal of neurosurgery, 1978, 48.6: 975-979.
22. YAMADA, Shokei, et al. Pathophysiology of tethered cord syndrome. Neurosurgery Clinics of North America, 1995, 6.2: 311-323.
23. TANI, Satoshi; YAMADA, Shokei; KNIGHTON, Robert S. Extensibility of the lumbar and sacral cord: Pathophysiology of the tethered spinal cord in cats. Journalof neurosurgery, 1987, 66.1: 116-123.
24. YAMADA, Shokei; SANDERS, Delmar C.; MAEDA, George. Oxidative metabolism during and following ischemia of cat spinal cord. Neurological research, 1981, 3.1: 1-16.
25. YAMADA, Shokei, et al. Pathophysiology of tethered cord syndrome and similar complex disorders. Neurosurgical focus, 2007, 23.2: 1-10.
26. GLENN, Chad, et al. Spinal cord detethering in children with tethered cord syndrome and Chiari type 1 malformations. Journal of Clinical Neuroscience, 2015, 22.11: 1749-1752.
27. MCLONE, David G., et al. Tethered cord as a cause of scoliosis in children with a myelomeningocele. Pediatric neurosurgery, 1990, 16.1: 8-13.
28. AHUJA, Kaustubh, et al. Is detethering necessary before deformity correction in congenital scoliosis associated with tethered cord syndrome: a meta-analysis of current evidence. European Spine Journal, 2021, 30: 599-611.
29. VANDERTOP, W. Peter. Syringomyelia. Neuropediatrics, 2013, 003-009.
30. BEAUMONT, Andrew; MUSZYNSKI, Cheryl A.; KAUFMAN, Bruce A. Clinical significance of terminal syringomyelia in association with pediatric tethered cord syndrome. Pediatric neurosurgery, 2007, 43.3: 216-221.
31. ERKAN, Kaan; UNAL, Faruk; KIRIS, Talat. Terminal syringomyelia in association with the tethered cord syndrome. Neurosurgery, 1999, 45.6: 1351.
32. BORDES, Stephen; JENKINS, Skyler; TUBBS, R. Shane. Defining, diagnosing, clarifying, and classifying the Chiari I malformations. Child's Nervous System, 2019, 35: 1785-1792.
33. LAWRENCE, Braden J., et al. Cerebellar tonsil ectopia measurement in type I Chiari malformation patients show poor inter-operator reliability. Fluids and Barriers of the CNS, 2018, 15: 1-10.
34. MILHORAT, Thomas H., et al. Association of Chiari malformation type I and tethered cord syndrome: preliminary results of sectioning filum terminale. Surgical neurology, 2009, 72.1: 20-35.
35. ISKANDAR, Bermans J., et al. Congenital tethered spinal cord syndrome in adults. Journal of neurosurgery, 1998, 88.6: 958-961.
36. YAMADA, Shokei; WON, Daniel; KIDO, Daniel K. Adult tethered cord syndrome: new classification correlated with symptomatology, imaging and pathophysiology. Neurosurgery Quarterly, 2001, 11.4: 260-275.
37. SEKERCI, Cagri Akin; TARCAN, Tufan. Primary and secondary tethered cord and association with pediatric lower urinary tract dysfunction. Current Bladder Dysfunction Reports, 2019, 14: 110-114.
38. PARK, Kwanjin. Urological evaluation of tethered cord syndrome. Journal of Korean Neurosurgical Society, 2020, 63.3: 358-365.
39. QIN, Sihe, et al. (ed.). Lower limb deformities: deformity correction and function reconstruction. Springer Nature, 2020.
40. BEN-SIRA, Liat, et al. Prenatal diagnosis of spinal dysraphism. Child's nervous system, 2013, 29: 1541-1552.
41. YUNDT, Kent D.; PARK, T. S.; KAUFMAN, Bruce A. Normal diameter of filum terminate in children: in vivo measurement. Pediatric neurosurgery, 1997, 27.5: 257-259.
42. SINGH, Suyash, et al. Dynamic magnetic resonance imaging parameters for objective assessment of the magnitude of tethered cord syndrome in patients with spinal dysraphism. Acta Neurochirurgica, 2019, 161: 147-159.
43. AOUN, Salah G., et al. The use of prone magnetic resonance imaging to rule out tethered cord in patients with structural spine anomalies: a diagnostic technical note for surgical decision-making. Cureus, 2019, 11.3.
44. MATSUZAKI, H., et al. The origin and significance of spinal cord pulsation. Spinal cord, 1996, 34.7: 422-426.
45. HALADOVÁ, Eva; NECHVÁTALOVÁ, Ludmila. Vyšetřovací metody hybného systému. Národní centrum ošetřovatelství a nelékaškých zdravotnických oborů, 2003.
46. SALA, Francesco, et al. Intraoperative neurophysiology in tethered cord surgery: techniques and results. Child's Nervous System, 2013, 29: 1611-1624.
47. PARK, Kwanjin. Urological evaluation of tethered cord syndrome. Journal of Korean Neurosurgical Society, 2020, 63.3: 358-365.
48. RACEKOVA, E.; FERCAKOVA, A.; ORENDACOVA, J. Neural stem cells: prospects for regeneration in adult CNS. Bratislavske lekarske listy, 2000, 101.8: 450-454.
49. HOFFMAN, Harold J., et al. Management of lipomyelomeningoceles: experience at the Hospital for Sick Children, Toronto. Journal of neurosurgery, 1985, 62.1: 1-8.
50. VAN LEEUWEN, Redmer; NOTERMANS, Nicolette C.; VANDERTOP, W. Peter. Surgery in adults with tethered cord syndrome: outcome study with independent clinical review. Journal of Neurosurgery: Spine, 2001, 94.2: 205-209.
51. LEE, Gabriel YF, et al. Surgical management of tethered cord syndrome in adults: indications, techniques, and long-term outcomes in 60 patients. Journal of Neurosurgery: Spine, 2006, 4.2: 123-131.
52. YAMADA, Shokei, et al. Tethered cord syndrome: overview of diagnosis and treatment. Neurological research, 2004, 26.7: 719-721.
53. JANDA, Vladimír. Svalové funkční testy. Grada Publishing as, 2004.
54. Manual Zebris FDM 1.10 [online]. [cit. 2023-08-04]. Dostupné z: https:// www.zebris.de/fileadmin/Editoren/zebris-PDF-Manuals/Medizin/Software/ Alte_Versionen/Manual_zebris_FDM_1.10_R5_EN.pdf
55. BASSON, Annalie, et al. The effectiveness of neural mobilization for neuromusculoskeletal conditions: a systematic review and meta-analysis. Journal of Orthopaedic & Sports Physical Therapy, 2017, 47.9: 593-615.
56. ABE, Yukio; DOI, Kazuteru; KAWAI, Shinya. An experimental model of peripheral nerve adhesion in rabbits. British journal of plastic surgery, 2005, 58.4: 533-540.
57. SATYARTHEE, Guru; JAGDEVAN, Aman. Prof. Shokei Yamada: An international neurosurgeon, regarded as father figure for adult tethered cord syndrome management and dedicated life for the advancement of intracranial arteriovenous malformation surgery. Asian Journal of Neurosurgery, 2019, 14.01: 341-342.
58. PANAGOPOULOS, Dimitrios, et al. The 100 most cited papers centered on tethered cord syndrome. Interdisciplinary Neurosurgery, 2020, 22: 100819.

Předběžná náplň práce

Syndrom fixované míchy je stav, při kterém je mícha na svém konci připevněna zesíleným filum terminale nebo tvoří adhezi s okolní míšní tkání. Klinicky se onemocnění projeví zejména jako paréza dolních končetin, bolesti zad, skolióza nebo urologická dysfunkce. Cílem bakalářské práce bylo vytvořit rešerši dostupných informacích o syndromu fixované míchy a zjistit potenciál fyzioterapie při léčbě syndromu. Z výsledků práce vyplynulo, že manuální terapie může mít velký potenciál při léčbě pacientů s fixovanou míchou. V kazuistice byl sledován pacient, který po dobu 6 měsíců prováděl každý den autotrakci páteře. Změny klinického obrazu pacienta byly hodnoceny na základě vybraných parametrů stability stoje a měřeny pomocí Zebris FDM Tredmill system. Při kontrolním vyšetření došlo k výraznému zlepšení všech měřených parametrů. Výsledek zkoumání naznačil možný pozitivní vliv trakce na syndrom fixované míchy.

Předběžná náplň práce v anglickém jazyce

Tethered cord syndrome is a neurological condition in which either the spinal cord is anchored by thickened filum terminale or is creating adhesions with surrounding spinal tissue. Progression of such condition leads to paresis of the lower limb, back pain, scoliosis or urological dysfunction. The goal of this thesis was to create a research of available informations about tethered cord syndrome and to explore possible potentials of physiotherapy treatment. Based on the thesis findings emerged a significant potential of manual therapy while treating patients with the tethered cord. In the case study patient with tethered cord was observed over the corse of 6 month and was educated to do autotraction of the spine daily. Changes of the patient’s clinical picture were evaluated based on selected standing stability parameters and measured using the Zebris FDM Tredmill system. While the control assessment a significant improvement of all the measured parameters was observed. Such result suggests a favourable effect of traction to the tethered cord syndrome.