Phosporylation is one of the most important postranslational modifications that effect celular processes on various levels. An addition of phosphate group to a protein will likely effect its 3D conformation. How phosphorylation effects function is well described, however its effects on 3D structure are less well understood. The aim of this work is to identify and summarize aarticles that study where does phosporylations occur and if and how (much) they change the 3D structure of proteins. The plan is to find out whether there are any structural regularities or rules that could be eventually used in a prediction of phosphorylations. The work will concentrate on studies that approach this problem in a "high- throughput" way and using bioinformatics methods. It is not meant to mention all works that study one particular phosphorylation on a single protein.
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