Development, implementation, and handling of femtosecond vibration spectroscopy at ELI beamlines laser facility: Femtosecond stimulated Raman and femtosecond mid-IR – direct observation of molecular motions (primary studied systems: carotenoids, photo switchable proteins, nuclear acids)
Název práce v češtině:
Vývoj, implementace a aplikace femtosekundové vibrační spektroskopie v ELI beamlines laser facility: Femtosekundová stimulovaná ramanovská a femtosekundová střední IR přímá sledování molekulárních pohybů (primárně sledované systémy: karotenoidy, světlem přepínané proteiny, nukleové kyseliny)
Název v anglickém jazyce:
Development, implementation, and handling of femtosecond vibration spectroscopy at ELI beamlines laser facility: Femtosecond stimulated Raman and femtosecond mid-IR – direct observation of molecular motions (primary studied systems: carotenoids, photo switchable proteins, nuclear acids)
Klíčová slova anglicky:
Raman, femtosecond, coherent, spectroscopy, vibration, ELI
Femtosecond Laser Pulses - Principles and Experiments, Professor Dr. Claude Rullière ISBN: 978-0-387-01769-3 (Print) 978-0-387-26674-9
Předběžná náplň práce v anglickém jazyce
Femtosecond lasers and experimental techniques using femtosecond pulses are at the moment among the most influential and progressive instruments in biophysics. Time resolved measurements that reach virtually quantum times are only a part of benefits brought by femtosecond lasers. High peak power of ultrafast lasers sources allows employment of multitude of nonlinear-optical techniques. Femtosecond vibration techniques progressed greatly in direction of multidimensional experiments that are femtosecond analogs of NMR techniques. While NMR is already established as a powerful tool to resolve molecular structures, its intrinsic time resolution is deeply below the times where the actual molecular dynamic takes place. In contrast to that multidimensional vibration experiments are performed on literary quantum time scales. The field is just in its infancy and extensive development is needed however this also brings a unique opportunity. At ELI beamlines facility an end-station devoted to femtosecond biophysics is going to be constructed with aim to incorporate maximum number of techniques suitable for available 1kHz laser sources. PhD would largely consist of state-of-the-art experiment construction that brings unique opportunity to acquire internationally valued experience with advance laser sources.
Applicant qualification: fluent English (international environment), basics of laser spectroscopy (ideally femtosecond), optics and quantum physics on the level of master diploma in biophysics, basic programming skills (especially: Matlab, LabVIEW), motivation and ability to work independently, essentials of molecular biology are welcome.
