Výsledky projektu Solubilizace a uvolňování nízkomolekulárních látek z multikompartmentových nanočástic s měkkým hydrofobním jádrem

As the main output of the project, the article clearly demonstrates that it is possible to prepare multilayer core-shell structures formed by coassembly of AB and CD block copolymers where A is a hydrophobic block, B is a polyionic block, C is a polyionic block with opposite charge to A and D is a neutral hydrophilic block. However, such a coassembly requires structural rearrangement of the hydrophobic core of parent AB micelles in order to form an interpolyelectrolyte BC layer between the core and the corona of hydrated D blocks which only occurs if the core is soft.