Pharmacology, pharmacodynamics, molecular mechanisms of drug action and drug
targets, pharmacokinetics, monitoring drug plasma concentration in relation to therapeutic
effects, adverse effects of drugs, system and disease oriented drug groups with
pharmacological profiles.
Cíl předmětu - angličtina
Poslední úprava: MAT89030 (15.10.2012)
Knowledge and skills to be acquired: prescription, general knowledge of the basic principles of pharmacology - pharmacokinetics, pharmacodynamics. Special knowledge of basic principles of pharmacology - knowledge of the groups of drugs according to anatomical systems and their diseases, including clinical indications and adverse effects.
Sylabus - angličtina
Poslední úprava: Jana Kolářová (08.03.2021)
Topics of lectures and seminars:
• Antihypertensives, pharmacotherapy of hypertension
• Antiobesity drugs
• Medicines that affect blood clotting
• Hypolipidemics
• Antiarrhythmics
• Antivirals
• Antibiotics
• Antidiabetics, insulins
• Pharmacotherapy of thyroid disorders
• Treatment of osteoporosis
• Immunopharmacology
• Cell and gene therapy, biological treatment
• Anticancer pharmacotherapy
• Remedies for respiratory diseases
• Pharmacotherapy of acute conditions
• Pharmacotherapy of pregnant women, lactating women, children and the elderly
• Drugs for diseases of the urogenital tract, drugs used in obstetrics
Literatura
Poslední úprava: MUDr. Nikolina Kutinová Canová, Ph.D. (06.09.2023)
Povinná:
. . In Katzung BG, Kruidering-Hall M, Trevor AJ. eds. . Katzung & Trevor's Pharmacology: Examination & Board Review, 12e. . USA: McGraw Hill Education, 2019, s. -. ISBN 978-1-259-64102-2..
. . In R.A. Harvey, Clark M.A, R. Finkel, J.A. Ray, K.W. Whalen (eds.). . Lippincott’s illustrated reviews: Pharmacology. . Philadelphia, US: Lippincott Williams & Wilkins, 2018, s. -608. ISBN 10-1451113145..
. . In H.P. Rang, M.M. Dale, J.M. Ritter (eds.). . Pharmacology. 8th edition, . London, UK: Churchill Livingstone, 2019, s. -776. ISBN 10-0702053627..
. . In L.L. Brunton, K.L. Parker (eds.), D.K Blumenthal., I.L Buxton. . Goodman & Gilman’s Manual of Pharmacology and Therapeutics. . New York City: , 2041, s. -642. ISBN 10-0071443436..
. . In Heinz Lüllmann , Klaus Mohr , Lutz Hein . Color Atlas of Pharmacology 5th Edition
. : Georg Thieme Verlag, 2018, s. -. ISBN 978-3132410657..
Metody výuky - angličtina
Poslední úprava: MUDr. Nikolina Kutinová Canová, Ph.D. (13.10.2023)
Pharmacology 2 B80386
Organization of teaching the master's form of General medicine + Erasmus study at the Institute of Pharmacology of the 1st Medical Faculty of Charles University for the winter semester 2023/2024:
Teaching takes place in the form of lectures and seminars.Attendance at lectures is recommended, attendance at seminars is mandatory.
An exceptions are the first three teaching weeks, when compulsory presence lectures take place (seminars do not take place).
Furthermore, according to the current epidemiological situation - full-time/presence teaching is assumed according to the schedule in the SIS, in the case of a worsened epidemiological situation, combined teaching will take place according to the rules listed below*.
Schedule of group seminars, teachers, and lecture rooms in the Institute of Pharmacology 1st Medical Faculty of Charles University, Albertov 4, Prague 2:
Thursdays 13.00 - 14.30 - Lectures in the lecture hall of the Institute of Pharmacology (since 26. 10. 2023)
Combined teaching (Distance and presence learning) of the master's form of study at the Institute of Pharmacology of the 1st Faculty of Medicine, Charles University, will take place only in the case of a worsened epidemiological situation*:
*Pharmacology will be taught according to syllabus published in the SIS. Teachers will be available to you by prior arrangement for possible personal consultations. Current contacts.
*Lectures
- take place exclusively remotely from the faculty portal for e-learning based on MS Teams ( https://e-learning.lf1.cuni.cz ).
- Lectures will take place at a time corresponding to the schedule of full-time teaching listed in the SIS online (live) via MS Teams for each subject separately ( eg. Pharmacology 2 – B80386 , Pharmacology – B83145 ), unless otherwise stated. The relevant reference to the team for each subject is given in the SIS.
- Lectures will be recorded and the recording will be available (for a maximum of 20 days) to the team in MS Teams for a specific subject.
*Seminars
- Attendance at seminars held in a combined distance and full-time form remains mandatory.
- Group teachers continue in distance learning (see below) and in ongoing checks on the fulfillment and mastery of the topic (entering examples to complete, quizzes, homework, research, essays, etc.).
- Study materials for seminars will be provided by group / circle teachers for self-study (via Moodle, MS Teams, e-mail, etc.) and / or presented online in real time (via MS Teams, Adobe Connect, Zoom, Skype, etc.).
- Compulsory tests listed for the given subject in the syllabus will take place in full-time/presence form at the Institute of Pharmacology of the First Medical Faculty of Charles University under valid hygienic and epidemic measures.
*Credit - conditions for granting credit:
1. satisfactory fulfillment of tasks assigned by group teachers during distance learning;
2. successful full-time completion of compulsory tests listed for the subject in the syllabus on the SIS.
*Exam
The course of exam will be adjusted according to the valid hygienic restrictions valid at the time of the test related to the coronavirus epidemic.
The examinations will take place in person on the dates listed in the SIS.
Distance testing will be possible very exceptionally after approval of the application by the head of the Institute of Pharmacology, 1st Faculty of Medicine, Charles University.
If you have any questions, do not hesitate to contact us.
MUDr. Nikolina Kutinová Canová, Ph.D. (ncano@lf1.cuni.cz ), representative for teaching
prof. MUDr. Ondřej Slanař, Ph.D. (oslan@lf1.cuni.cz ), head of the department
Rozpis výuky -
Rozpis semestrální
Výukový týden
Datum
Od - Do
Typ výuky
Téma
Učitel
Soubory
Poznámka
Hodnocení
1
04.10.2023
14:15 - 16:00
přednáška
Heart failure. Diuretics. Therapy of hypertension.
The attendance is obligatory for all students.
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
MUDr. Pavel Ryšánek, Ph.D.
Seminars are canceled, however, the attendance at lectures is obligatory for all students (see schedule of lectures).
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
průměr: 4, hodnoceno: 2x
2
12.10.2023
12:30 - 14:15
přednáška
Pharmacotherapy of ischemic heart disease. Antiarrhythmic drugs
The attendance is obligatory for all students.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4, Prague 2, 128 00 (except 4/10 and 18/10/2023)
PharmDr. Jan Hartinger, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4, Prague 2, 128 00 (except 4/10 and 18/10/2023)
Seminars are canceled, however, the attendance at lectures is obligatory for all students (see schedule of lectures).
průměr: 4, hodnoceno: 7x
3
18.10.2023
14:15 - 16:00
přednáška
Antimicrobials I., II.
The attendance is obligatory for all students.
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
MUDr. Olga Bartošová, Ph.D.
Seminars are canceled, however, the attendance at lectures is obligatory for all students (see schedule of lectures). The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
průměr: 2, hodnoceno: 3x
4
24.10.2023
13:00 - 14:30
seminář
Pharmacotherapy of bacterial diseases - case reports.
Tuesdays from 01:00 PM to 02:30 PM – groups 4051 and 4052 + Erasmus
Wednesdays from 02:45 PM to 04:15 PM – groups 4053 and 4054
průměr: 3, hodnoceno: 2x
25.10.2023
14:45 - 16:15
seminář
Pharmacotherapy of bacterial diseases - case reports.
Tuesdays from 01:00 PM to 02:30 PM – groups 4051 and 4052 + Erasmus
Wednesdays from 02:45 PM to 04:15 PM – groups 4053 and 4054
průměr: 1, hodnoceno: 1x
26.10.2023
13:00 - 14:30
přednáška
Antivirals, antifungals, antiparasitics.
PharmDr. Irena Štenglová Netíková, Ph.D.
For technical reasons, the lecture on October 26 at 1:00 p.m. has been moved to room KBLDP2 at the dean's office at Kateřinská 32.
průměr: 2, hodnoceno: 4x
5
31.10.2023
13:00 - 14:30
seminář
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
průměr: 4, hodnoceno: 2x
01.11.2023
14:45 - 16:15
seminář
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
průměr: 5, hodnoceno: 2x
02.11.2023
13:00 - 14:30
přednáška
Anticoagulants and anti-platelet drugs; fibrinolytics and antifibrinolytics.
PharmDr. Jan Hartinger, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4, Prague 2, 128 00 (except 4/10, 18/10, 26/10/2023)
průměr: 4, hodnoceno: 5x
6
07.11.2023
13:00 - 14:30
seminář
TDM (therapeutic drug monitoring) - separate schedule.
průměr: 4, hodnoceno: 1x
08.11.2023
14:45 - 16:15
seminář
TDM (therapeutic drug monitoring) - separate schedule.
průměr: 4, hodnoceno: 1x
09.11.2023
13:00 - 14:30
přednáška
Hypolipidemics. An overview of the possibilities of pharmacological influence of the metabolic syndrome.
MUDr. Nikolina Kutinová Canová, Ph.D.
průměr: 4, hodnoceno: 2x
7
14.11.2023
13:00 - 14:30
seminář
Hypertension therapy overview + case reports.
15.11.2023
14:45 - 16:15
seminář
Hypertension therapy overview + case reports.
16.11.2023
13:00 - 14:30
přednáška
Overview of hormones. Corticosteroids.
MUDr. Olga Bartošová, Ph.D.
8
21.11.2023
13:00 - 14:30
seminář
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction.
22.11.2023
14:45 - 16:15
seminář
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction.
23.11.2023
13:00 - 14:30
přednáška
Drugs used in diseases of the respiratory system.
prof. MUDr. Ondřej Slanař, Ph.D.
9
28.11.2023
13:00 - 14:30
seminář
Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
29.11.2023
14:45 - 16:15
seminář
Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
30.11.2023
13:00 - 14:30
přednáška
Drugs used in diseases of gastrointestinal tract.
MUDr. Nikolina Kutinová Canová, Ph.D.
10
05.12.2023
13:00 - 14:30
seminář
Pharmacotherapy of respiratory tract system diseases - case reports.
06.12.2023
14:45 - 16:15
seminář
Pharmacotherapy of respiratory tract system diseases - case reports.
07.12.2023
13:00 - 14:30
přednáška
Cell and gene therapy, biological treatment. Immunopharmacology
prof. MUDr. Ondřej Slanař, Ph.D.
11
12.12.2023
13:00 - 14:30
seminář
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
13.12.2023
14:45 - 16:15
seminář
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
Pharmacotherapy of acute conditions – case studies.
20.12.2023
14:45 - 16:15
seminář
Pharmacotherapy of acute conditions – case studies.
21.12.2023
13:00 - 14:30
přednáška
Drugs used to treat diseases of the urogenital tract, drugs used in obstetrics.
MUDr. Olga Bartošová, Ph.D.
13
02.01.2024
13:00 - 14:30
seminář
Pharmacotherapy in rheumatology: rheumatoid arthritis, osteoarthritis, gout.
03.01.2024
14:45 - 16:15
seminář
Pharmacotherapy in rheumatology: rheumatoid arthritis, osteoarthritis, gout.
04.01.2024
13:00 - 14:30
přednáška
Pharmacotherapy in pregnant women, breastfeeding, children and the elderly.
MUDr. Karolína Hronová, Ph.D.
14
09.01.2024
13:00 - 14:30
seminář
Repetition of psychotropic drugs.
10.01.2024
14:45 - 16:15
seminář
Repetition of psychotropic drugs.
11.01.2024
13:00 - 14:30
přednáška
Drugs in palliative therapy
MUDr. Olga Bartošová, Ph.D.
15
16.01.2024
13:00 - 14:30
seminář
Test - psychotropic drugs. Repetition of prescription writing. CREDIT
17.01.2024
14:45 - 16:15
seminář
Test - psychotropic drugs. Repetition of prescription writing. CREDIT
18.01.2024
13:00 - 14:30
přednáška
Acute and chronic drug intoxication – treatment and antidotes.
PharmDr. Jan Hartinger, Ph.D.
Schedule semestral
Educational week
Date
From - To
Education type
Theme
Teacher
Files
Note
Hodnocení
1
04.10.2023
14:15 - 16:00
lecture
Heart failure. Diuretics. Therapy of hypertension.
The attendance is obligatory for all students.
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
MUDr. Pavel Ryšánek, Ph.D.
Seminars are canceled, however, the attendance at lectures is obligatory for all students (see schedule of lectures).
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
průměr: 4, hodnoceno: 2x
2
12.10.2023
12:30 - 14:15
lecture
Pharmacotherapy of ischemic heart disease. Antiarrhythmic drugs
The attendance is obligatory for all students.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4, Prague 2, 128 00 (except 4/10 and 18/10/2023)
PharmDr. Jan Hartinger, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4, Prague 2, 128 00 (except 4/10 and 18/10/2023)
Seminars are canceled, however, the attendance at lectures is obligatory for all students (see schedule of lectures).
průměr: 4, hodnoceno: 7x
3
18.10.2023
14:15 - 16:00
lecture
Antimicrobials I., II.
The attendance is obligatory for all students.
The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
MUDr. Olga Bartošová, Ph.D.
Seminars are canceled, however, the attendance at lectures is obligatory for all students (see schedule of lectures). The lecture is held in the lecture hall of the Department of Rehabilitation Medicine, Albertov 7, Praha 2, 128 00
průměr: 2, hodnoceno: 3x
4
24.10.2023
13:00 - 14:30
seminar
Pharmacotherapy of bacterial diseases - case reports.
Tuesdays from 01:00 PM to 02:30 PM – groups 4051 and 4052 + Erasmus
Wednesdays from 02:45 PM to 04:15 PM – groups 4053 and 4054
průměr: 3, hodnoceno: 2x
25.10.2023
14:45 - 16:15
seminar
Pharmacotherapy of bacterial diseases - case reports.
Tuesdays from 01:00 PM to 02:30 PM – groups 4051 and 4052 + Erasmus
Wednesdays from 02:45 PM to 04:15 PM – groups 4053 and 4054
průměr: 1, hodnoceno: 1x
26.10.2023
13:00 - 14:30
lecture
Antivirals, antifungals, antiparasitics.
PharmDr. Irena Štenglová Netíková, Ph.D.
For technical reasons, the lecture on October 26 at 1:00 p.m. has been moved to room KBLDP2 at the dean's office at Kateřinská 32.
průměr: 2, hodnoceno: 4x
5
31.10.2023
13:00 - 14:30
seminar
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
průměr: 4, hodnoceno: 2x
01.11.2023
14:45 - 16:15
seminar
Test on antimicrobials (antibiotics, antivirals, antifungals, antiparasitics).
Repetition of pharmacokinetics (calculations - examples).
průměr: 5, hodnoceno: 2x
02.11.2023
13:00 - 14:30
lecture
Anticoagulants and anti-platelet drugs; fibrinolytics and antifibrinolytics.
PharmDr. Jan Hartinger, Ph.D.
The lectures are held in the lecture hall of the Institute of Pharmacology, Albertov 4, Prague 2, 128 00 (except 4/10, 18/10, 26/10/2023)
průměr: 4, hodnoceno: 5x
6
07.11.2023
13:00 - 14:30
seminar
TDM (therapeutic drug monitoring) - separate schedule.
průměr: 4, hodnoceno: 1x
08.11.2023
14:45 - 16:15
seminar
TDM (therapeutic drug monitoring) - separate schedule.
průměr: 4, hodnoceno: 1x
09.11.2023
13:00 - 14:30
lecture
Hypolipidemics. An overview of the possibilities of pharmacological influence of the metabolic syndrome.
MUDr. Nikolina Kutinová Canová, Ph.D.
průměr: 4, hodnoceno: 2x
7
14.11.2023
13:00 - 14:30
seminar
Hypertension therapy overview + case reports.
15.11.2023
14:45 - 16:15
seminar
Hypertension therapy overview + case reports.
16.11.2023
13:00 - 14:30
lecture
Overview of hormones. Corticosteroids.
MUDr. Olga Bartošová, Ph.D.
8
21.11.2023
13:00 - 14:30
seminar
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction.
22.11.2023
14:45 - 16:15
seminar
Test - pharmacotherapy of cardiovascular system (antihypertensives and other vasodilators, antianginal drugs, pharmacotherapy of acute and chronic heart failure, antiarrhythmics).
Pharmacotherapy of obesity and thyroid dysfunction.
23.11.2023
13:00 - 14:30
lecture
Drugs used in diseases of the respiratory system.
prof. MUDr. Ondřej Slanař, Ph.D.
9
28.11.2023
13:00 - 14:30
seminar
Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
29.11.2023
14:45 - 16:15
seminar
Drugs affecting homeostasis of calcium and other minerals.
Pharmacotherapy of osteoporosis.
30.11.2023
13:00 - 14:30
lecture
Drugs used in diseases of gastrointestinal tract.
MUDr. Nikolina Kutinová Canová, Ph.D.
10
05.12.2023
13:00 - 14:30
seminar
Pharmacotherapy of respiratory tract system diseases - case reports.
06.12.2023
14:45 - 16:15
seminar
Pharmacotherapy of respiratory tract system diseases - case reports.
07.12.2023
13:00 - 14:30
lecture
Cell and gene therapy, biological treatment. Immunopharmacology
prof. MUDr. Ondřej Slanař, Ph.D.
11
12.12.2023
13:00 - 14:30
seminar
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
13.12.2023
14:45 - 16:15
seminar
Test - pharmacotherapy of the respiratory tract system (with the exception of infectious diseases).
Drugs affecting hemocoagulation: case reports (as a repetition and supplement to the lecture).
