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Pathophysiology_teaching and exam 2019_2020_dent.pdf | Patofyziologie - výuka a zkouška v akademickém roce 2019/2020 | doc. MUDr. Jan Cendelín, Ph.D. |
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Poslední úprava: doc. MUDr. Jan Cendelín, Ph.D. (21.11.2022)
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Poslední úprava: doc. MUDr. Jan Cendelín, Ph.D. (21.11.2022)
For the practical exercises, the student must be theoretically prepared for the topic of the given class and is obliged to acquaint himself with the guideline for the given experiment or task (webpage of the Department of Pathophysiology: http://www.lfp.cuni.cz/patofyziologie, textbook Sobotka et al.: Pathophysiology – Laboratory Exercises). Students, who did not attend the class in time, will be not admitted to the class. During the unfavorable epidemiological situation, students are required to have their mouths and noses covered and to follow the rules set by the Ministry of Health, the Ministry of Education, Charles University, or the Medical Faculty of Charles University in Pilsen. Otherwise, they will not be admitted to the class with the penalty of unexcused absence.
Prerequisites are knowledge from the fields to which the subject pathological physiology follows, i.e. anatomy, histology, embryology, biology, genetics, chemistry and biochemistry, biophysics, physiology and microbiology.
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Poslední úprava: doc. MUDr. Jan Cendelín, Ph.D. (21.11.2022)
Winter and summer semester education is finalized with credits. Both credits are conditions for admission to the exam as well as for registration for the exam.
Conditions for the credit
1. Active attending practical exercises – 1 absence is allowed. For the practical exercises, the student must be theoretically prepared for the topic of the given class and is obliged to acquaint himself with the guideline for the given experiment or task (se study literature). Students, who did not attend the class in time, will be not admitted to the class. 2. Submitting of correctly elaborated protocols of all experiments and practical exercises verified by the teacher.
The conditions of the credits for students having an individual study plan, who enrolled pathophysiology for the second time, will be appointed individually in dependence on study duties passed in the previous academic year. These conditions will not exceed the range of above specified general duties. |
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Poslední úprava: doc. MUDr. Jan Cendelín, Ph.D. (21.11.2022)
Mandatory: Sobotka et al.: Pathophysiology – Laboratory Exercises. 2013, Karolinum, 2013 McPhee, Hammer et al.: Pathophysiology of Disease: An Introduction to Clinical Medicine. The McGraw-Hill Companies, Inc., 6th Edition 2010 (or later issues) Educational materials published on the webpage of the Department of Pathophysiology and educational portals of the Faculty of Medicine in Pilsen, Charles University
Recommended: Hueher et al.: Understanding Pathophysiology. Elsevier, 2017 McCance and Huether: Pathophysiology, the Biologic Basis for Disease in Adults and Children. Elsevier, 2019 Banasik and Copstead: Pathophysiology. Elsevier, 2019 Hulín et al.: Pathophysiology. Slovak Academic Press, 1997 (or later issues) Silbernagl and Lang: Color Atlas of Pathophysiology. 3rd edition, Georg Thieme Verlag KG, 2016 Price and Wilson et al.: Pathophysiology – Clinical concepts of disease processes. Mosby, Inc., 2003 Guyton: Human physiology and mechanisms of disease. W. B. Saunders Company, the latest issue |
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Poslední úprava: doc. MUDr. Jan Cendelín, Ph.D. (21.11.2022)
The student is obliged to register for the exam before the deadline using SIS (other ways of registration will not be accepted). Registration is necessary for the regular term as well as for potential 1st re-examination or 2nd re-examination. The condition for registration for the exam is obtaining a credit.
The exam consists of a practical exam and oral exam. The required knowledge is based on the list of exam questions and the syllabus of the subjects Pathological Physiology I and Pathological Physiology II (for detailed syllabus and list of questions for the practical exam and oral exam see webpage of the department of pathophysiology: http://patofyziologie.lfp.cuni.cz/?lang=en). Practical exam consists of question related to practical exercises. Failure in the practical exam means classification of the exam “fail”.
Oral exam consists of 3 questions related to the syllabus of the subject. To pass the oral exam, the student must show sufficient knowledge in each of these 3 questions.
Final classification takes into consideration not only the performance in the oral exam but also the classification of the practical exam.
Practical and oral exams constitute one complex and cannot be separated into two examination terms. In the case of classification of any part of the exam "fail", the student is subjected to both the practical and oral exam again in the 1st or 2nd reexamination.
Due to capacity reasons, the exam can be divided into several days within the given exam date. Students are required to attend the appropriate stage of the exam according to the schedule or examiner's instructions.
Standardly, the exam is on-site. In the case of the remote form of examination (if the circumstances do not allow for a standard examination and in accordance with the rules in force at the time of the exam), an interview will be conducted by Zoom, MS Teams or similar tool. It is therefore necessary for the student to be equipped with an internet connection, a computer with a camera and a microphone. In the case of remote examination, the questions will be selected by the teacher, the exam will start immediately after the questions have been asked and the student will not have time to prepare. |
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Poslední úprava: doc. MUDr. Jan Cendelín, Ph.D. (21.11.2022)
Syllabus of pathological physiology – dental medicine The student knows the facts in the field of general and special pathophysiology, can present and logically organize them, recognize and evaluate their importance, name examples of described phenomena. The student is oriented in the problem and can explain pathophysiological mechanisms of the diseases, explain how and why pathological processes happen and develop. The student can find and explain a context and relations between knowledge of various areas of pathophysiology, understand and use interdependence of individual organ systems in normal as well as pathological states. The student has knowledge of subjects which pathophysiology follows up on, i.e. anatomy, histology, embryology, biology chemistry and biochemistry, biophysics, physiology and microbiology. The student can use this knowledge to understand pathophysiology and can find and explain their relations.
General pathophysiology Introduction to the subject, definition of basic terms, etiology, pathogenesis Disease and its course, manifestation of diseases Etiological factors Intrinsic etiological factors (constitution, reactivity, epigenetics, heredity) Extrinsic etiological factors (physical, chemical, biological, social) Developmental disorders Diseases and disorders linked to a certain age Gametopathy, blastopathy, embryopathy, fetopathy, perinatal damage, teratogenic factors Growth disorders - nanism, gigantism Aging, causes and mechanisms of aging, theory of aging, consequences of aging Terminal states, death - clinical and biological death, causes and mechanisms of death, signs of death, dying and its stages, persistent vegetative state, locked-in syndrome Stress - the concept of general adaptation syndrome, stress phases, relation of stress to pathogenesis of disease, stress diseases, stress axes disturbances Pathophysiology of immunity – immunodeficiency, allergy, autoimmune diseases, inflammation, transplantation Pathophysiology of thermoregulation – overheating, hypothermia, fever, malignant hyperthermia Pathophysiology of tumors - classification of tumors, tumorigenesis, metastasis, paraneoplastic phenomena Acid-base balance and its disorders Pathophysiology of body fluids – changes of volume and osmolality, edema
Special pathophysiology – pathophysiology of organ systems Pathophysiology of the cardiovascular system Heart defects, disturbances of peripheral blood circulation, atherosclerosis, ischemic heart disease, arrhythmias, arterial hypertension, cardiac insufficiency and failure, pulmonary hypertension, thromboembolic disease, circulatory shock Pathophysiology of the blood Pathophysiology of red blood cells, pathophysiology of leukocytes, hemorrhagic diathesis, thrombotic states Pathophysiology of breathing Hypoxia, cyanosis, obstructive and restrictive disorders of lung ventilation, disorders of lung diffusion and perfusion, disorders of breathing regulation, acute respiratory distress syndrome Pathophysiology of the excretory system Pathophysiology of acute and chronic renal failure, uremic syndrome Pathophysiology of the endocrine system Pathophysiology of endocrine function of the hypothalamus, neuro- and adenohypophysis Pathophysiology of the thyroid gland – thyroid hormones Pathophysiology of the adrenal cortex and medulla Pathophysiology of the parathyroid glands Pathophysiology of metabolism and internal environment Pathophysiology of energetic metabolism Disorder of glycaemia regulation, diabetes mellitus Pathophysiology of calcium metabolism Pathophysiology of protein and amino acids metabolism, nitrogen balance Pathophysiology of lipid and carbohydrate metabolism Pathophysiology of nutrition Eating disorders, malnutrition, anorexia, bulimia, pathophysiology of starvation, obesity Rational diet, carbohydrates, fats and proteins as food components Hypovitaminoses and hypervitaminoses, lack and excess of minerals and trace elements Pathophysiology of the gastrointestinal tract Pathophysiology of the oral cavity, stomach, small and large intestine Pathophysiology of exocrine pancreas Pathophysiology of the liver, portal hypertension, ascites and hyperbilirubinemia Pathophysiology of the nervous system General causes of disorders and illnesses of the nervous system Disorders of peripheral nerves Pathophysiology of the spinal cord, brain stem, cerebellum, hypothalamus, basal ganglia Pathophysiology of vegetative nervous system Pathophysiology of neuromuscular transmission Pathophysiology of learning and memory and symbolic functions Neurodegenerative and demyelinating disorders Pathophysiology of epilepsy Pathophysiology of the motor system, paralysis, ataxias Pathophysiology of sleep and biological rhythms Pathophysiology of brain edema and intracranial hypertension Pathophysiology of the sensory systems - pathophysiology of somatosensory system, pain
Practical knowledge and skills Statistics Laboratory animals and principles of laboratory work Electrocardiography, principles, ECG record description, diagnosis Electroencephalography Using electricity in medicine, active and passive electrical properties of tissues Injection technique Local and general anesthesia, complex management of general anesthesia Surgical instruments and sewing materials Definition of concepts, methods, preparation of the surgical field Basic surgical procedures – surgical knots and stitches, asepsis, antisepsis Examination of hemorrhagic diatheses, Measurement of blood pressure Examination of pulmonary ventilation – spirometry, obstructive and restrictive disorders Detailed syllabus is available on the webpage of the department of pathophysiology: http://patofyziologie.lfp.cuni.cz/?page_id=115&lang=en |
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Poslední úprava: doc. MUDr. Jan Cendelín, Ph.D. (21.11.2022)
Winter and summer semester education is finalized with credits. Both credits are conditions for admission to the exam as well as for registration for the exam.
Conditions for the credit
1. Active attending practical exercises – 1 absence is allowed. For the practical exercises, the student must be theoretically prepared for the topic of the given class and is obliged to acquaint himself with the guideline for the given experiment or task (se study literature). Students, who did not attend the class in time, will be not admitted to the class. 2. Submitting of correctly elaborated protocols of all experiments and practical exercises verified by the teacher.
The conditions of the credits for students having an individual study plan, who enrolled pathophysiology for the second time, will be appointed individually in dependence on study duties passed in the previous academic year. These conditions will not exceed the range of above specified general duties. |