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Předmět, akademický rok 2022/2023
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Clinical Biochemistry - EA0110126
Anglický název: Clinical Biochemistry
Zajišťuje: Ústav klinické biochemie a hematologie (14-540)
Fakulta: Lékařská fakulta v Plzni
Platnost: od 2021
Semestr: zimní
Body: 2
E-Kredity: 2
Způsob provedení zkoušky: zimní s.:
Rozsah, examinace: zimní s.:30/0, Z+Zk [HS]
Rozsah za akademický rok: 6 [dny]
Počet míst: neurčen / neurčen (neurčen)
Minimální obsazenost: neomezen
Virtuální mobilita / počet míst: ne
Stav předmětu: vyučován
Jazyk výuky: angličtina
Způsob výuky: prezenční
Úroveň:  
Pro druh:  
Další informace: http://lms.lfp.cuni.cz/course/view.php?id=170
Poznámka: odhlásit z termínu zkoušky při nesplněné rekvizitě
Garant: MUDr. Daniel Rajdl, Ph.D.
prof. MUDr. Jaroslav Racek, DrSc.
Vyučující: MUDr. Roman Cibulka, Ph.D.
MUDr. Richard Pikner, Ph.D.
prof. MUDr. Jaroslav Racek, DrSc.
MUDr. Daniel Rajdl, Ph.D.
Ing. Václav Senft
Je korekvizitou pro: EA0112038, EA0112033, EA0112029, EA0112023, EA0112019, EA0112024
Je neslučitelnost pro: EAP0105540
Je záměnnost pro: EAP0105540
Anotace - angličtina
Poslední úprava: MUDr. Daniel Rajdl, Ph.D. (01.02.2017)
Seminars take place in the new seminar room of our institute - University Hospital Lochotin, entrance B, 2nd floor, next to the elevators.

Medical students will gain knowledge of the organization and work of a clinical laboratory. They will become acquainted with problems of preanalytical influences on the results of laboratory examinations, methods for estimation of reference limits, and questions of "evidence-based medicine" (i.e., problems of diagnostic sensitivity and specificity, concept of a risk factor, etc.). The main outcome is to help students to understand indication and interpretation of the most common laboratory tests. The classes are interactive, focusing on proper understanding of problems rather than memorizing knowledge. Some classes begin with readiness quiz to ensure some basic knowledge before starting more complicated topics. The classes are supported by e-learning course: http://lms.lfp.cuni.cz/course/view.php?id=170 where you can find more information and study materials (texts, presentations, study quizzes).
Literatura - angličtina
Poslední úprava: MUDr. Daniel Rajdl, Ph.D. (01.02.2017)
  • Course Clinical biochemistry, accessible on-line from WWW: http://lms.lfp.cuni.cz/course/view.php?id=170 (login via CAS), cited on 1.2.2017
  • Beckett, G.J., Walker, S.W., Rae, P., Ashby,P.: Lecture Notes Clinical Biochemistry.
    8thEdition, Wiley-Blackwell, Oxford, London, Edinburgh etc., 2010, 344 pp. ISBN: 978-1-4051-9305-4
    9thEdition, Wiley-Blackwell, Oxford, London, Edinburgh etc., 2013, 344 pp. ISBN: 9781118272114
Požadavky ke zkoušce - angličtina
Poslední úprava: MUDr. Daniel Rajdl, Ph.D. (02.09.2020)

Attening seminars (1 absence allowed) ; you have to successfully passed 5 of 6 credit quizzes (see literature for direct access to the course, where questions from these quizzes are) to receive credit. You don´t need to wear spacial clothes (white coat ...) during seminars. We recommend to have a smartphone or laptop and you should be prepaired according to instructions that you will receive by e-mail one week before your teaching block. The exam is in the form of a complex written quiz with standardized points. Minumum points to pass is 65 %.

Sylabus - angličtina
Poslední úprava: MUDr. Daniel Rajdl, Ph.D. (04.12.2020)

More accurate learning outcomes can be found in the e-learning course.

  1. Preanalytical influences on laboratory tests.
  2. Reference values, methods of their determination.
  3. Analytical properties of laboratory methods, quality control.
  4. Diagnostic sensitivity and specificity, their relationship, laboratory screening.
  5. Basic examination of urine.
  6. Non-protein nitrogen substances.
  7. Electrophoresis of serum proteins, electrophoretic types.
  8. Significance of determination of serum proteins.
  9. Na, K, Cl - clinical significance of determination.
  10. Ca, P, Mg - clinical significance of determination.
  11. Trace elements.
  12. Vitamins.
  13. Thyroid hormones.
  14. Hormones of hypothalamus and pituitary gland.
  15. Hormones of adrenal cortex.
  16. Metabolic acidosis.
  17. Metabolic alkalosis.
  18. Respiratory disorders of acid-base balance.
  19. Combined disorders of acid-base balance.
  20. Osmolality - clinical significance.
  21. Serum lipids: metabolism and relationship to atherogenesis.
  22. Risk factors of atherosclerosis (with exception of lipids).
  23. Laboratory examinations of patients with liver diseases.
  24. Laboratory diagnostics of jaundice.
  25. Laboratory markers of bone metabolism.
  26. Functional tests of kidneys.
  27. Laboratory examination of gastrointestinal tract.
  28. Laboratory diagnostics of diabetes mellitus.
  29. Laboratory control of diabetes mellitus.
  30. Laboratory diagnostics of myocardial infarction.
  31. Laboratory markers of malignancies (tumour markers).
  32. Cytochemical examination of cerebrospinal fluid.
  33. Hereditary metabolic diseases - laboratory diagnostics.
  34. Laboratory examinations of patients with urinary stones.
  35. Laboratory examinations in pregnancy.
  36. Peculiarities of laboratory examinations of infants.
  37. Basic principles of toxicological examinations.
Studijní opory - angličtina
Poslední úprava: MUDr. Daniel Rajdl, Ph.D. (25.09.2020)

Supplementary online course is at https://lms.lfp.cuni.cz/course/view.php?id=172

 
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