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    Bioorganic Chemistry (0531VD130008)

    Faculty: Faculty of Pharmacy in Hradec Králové
    Study programme: Bioorganic Chemistry (P0531D130008)
    Form of study: full-time
    Type of study: doctoral
    Language of instruction: Czech
    Expected minimum number of accepted students Expected number of accepted students: 8
    Standard length of study: 4 years
    Application type: Online, Paper

    Rate of admitted and total applicants in the past academic year

    2 / 2

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      Application submission date 1: 30.04.2025
      Application submission date 2: 02.09.2025
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      Charge for an on-line application: 810 CZK
      Charge for a paper application: 860 CZK
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      Postgraduate study in Bioorganic Chemistry serves for the education of chemical experts with emphasis on the structure and functions of small organic molecules in living organisms, and on the possibility of influencing biological processes in these organisms through the action of such molecules. The programme is thus directed towards the study of all aspects of organic compounds, which are indispensable for the structure and functioning of living organisms. The broad spectrum of these compounds includes molecules with a building (primary metabolites) function, signaling function, activating or deactivating function in relationship to strategic proteins with in the living organisms, and also compounds, which are produced by these organisms (natural products, secondary metabolites, metabolites of xenobiotics). The study is founded on the structure and synthesis of organic compounds with a focus on natural products, heterocycles and other organic compounds, which are capable of modulating biological processes. Elucidation of the function of such compounds as parts of biological structures as well as that of their influence on biological processes and possibility to modify this influence through structural changes are no less important. Bioorganic Chemistry thus serves as a link between Organic Chemistry and biomedical disciplines, and partially overlaps with Pharmaceutical and Medicinal Chemistry. Bioorganic Chemistry is, however, more general than the latter two programmes, which are primarily focused on the study and development of drugs, ie. a more limited subgroup of biologically active compounds.

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      Rámcový obsah přijímací zkoušky

      Ústní zkouška z organické chemie - systematika a reaktivita organických sloučenin.
      Část zkoušky v anglickém jazyce pro posouzení znalosti angličtiny (alespoň znalost na úrovni B2 je podmínkou).

      Doplňující podmínky pro bonifikaci (např. praxe)

      Řádně ukončené studium v magisterském studijním programu farmacie, přírodovědného nebo chemického zaměření (hodnoceno 2 body).
      Diplomová práce v oboru organická, bioorganická a farmaceutická chemie (hodnoceno 3 body).
      Uvedení předpokládaného školícího pracoviště a uvedení souhlasu konkrétního školitele s vedením plánovaného doktorandského projektu (hodnoceno max. 5 body).

      Kritéria pro vyhodnocení přijímací zkoušky

      1. Úroveň odborných znalostí - posouzena na základě odpovědí na otázky z okruhu témat uvedených v Rámcovém obsahu přijímací zkoušky (lze získat max. 10 bodů)
      2. Předložený doktorandský projekt - hodnocena je komplexnost projektu, moderní metodické přístupy pro řešení a návaznost projektu na již řešená témata v oborové radě (lze získat max. 10 bodů)

      Minimální bodová hranice pro přijetí je 20 bodů. 
      Děkan rozhodne o přijetí toho/těch uchazeče/uchazečů, který/kteří splnil/i podmínky přijímacího řízení a zároveň se podle počtu dosažených bodů umístil/i v pořadí odpovídajícím předem stanovenému předpokládanému počtu přijímaných uchazečů pro konkrétní program.

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      Admission to Doctoral studies is conditioned by successful completion of a Master's study programme.



      Verification method: entrance exam
      Confirmation date (of entrance exam) from: 02.06.2025 Until: 20.06.2025
      Alternative date (of entrance exam): 07.07.2025 Until: 11.07.2025
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      Graduate in Bioorganic Chemistry has mastered the principles of the chemical disciplines, and has a broad knowledge of Organic and Bioorganic Chemistry, focused on organic molecules which are essential for life and functioning of living organisms, are produced by these organisms or are capable of influencing biological processes inside them. He/she has basic understanding of the nature of the bioassays used to test the properties of organic compounds. He/she is capable of using chemical literature (primary and secondary sources), including search in computer databases, independent data collecting and their critical assessment. He/she is expert at chemical laboratory techniques (methodology of synthesis, detection, isolation and purification of compounds) and at instrumental methods for structure elucidation (IR, MS, NMR). The graduate is proficient at designing and evaluating the structures of compounds with potential influence on living organisms, and assessing the influence of structural changes on their biological and physical properties. He/she is able to plan the syntheses of such compounds, to critically evaluate existing/designed syntheses and to elucidate the structure of the compounds by instrumental analytical methods. He/she is capable of evaluating the latest findings in the field, putting his/her own results in their context and adapting to the latest trends in the field. He/she can independently publish his/her results in scientific journals, prepare presentations and participate in national and international conferences with English as the language of communication. The graduate is capable of communicating with experts in the related biomedical and medical disciplines. He/she can be employed in academia, and in state and company laboratories dealing with organic compounds/products with defined, mainly biological, properties, ie. primarily in chemical and pharmaceutical industry.
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      Tuition [CZK] / per period: 1000 CZK / year