Human genetics - OENBB1710Z

• Title: Human genetics
• Guaranteed by: Katedra biologie a environmentálních studií (41-KBES)
• Faculty: Faculty of Education
• Actual: from 2023
• Semester: both
• E-Credits: 4
• Examination process: oral
• Hours per week, examination: 2/0, Ex [HT]
• Capacity: winter:unknown / unknown (5); summer:unknown / unknown (5)
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: not taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Note: course can be enrolled in outside the study plan; enabled for web enrollment; priority enrollment if the course is part of the study plan; you can enroll for the course in winter and in summer semester
• Guarantor: RNDr. Edvard Ehler, Ph.D.

Annotation

Last update: Kateřina Esserová, DiS. (11.06.2019)

In human genetics course we will cover broad range of topics starting from the organization of human genomes, its evolution and phylogenetic relations, we will briefly address the technologies needed for analyzing of the genome. The students will be introduced to the basic theories of human evolutionary genetics and the main forces that form our genetics diversity (selection, migration, genetic drift, mutation). Genetic background of diseases and inherited disorders will be also covered. This course is suitable for students with at least some prior knowledge from genetics, cell biology and population biology, which will allow us to discuss more advanced topics.

Descriptors

Last update: RNDr. Edvard Ehler, Ph.D. (11.02.2021)

Lectures will be held online using MS Teams platform, approximately every 2 weeks. Students are expected to work individually. Further information will be given by email at the beginning of the semester.

Literature

Last update: Kateřina Esserová, DiS. (11.06.2019)

Jobling, Mark, Matthew Hurles, and Chris Tyler-Smith. Human evolutionary genetics: origins, peoples & disease. Garland Science, 2013.

Nussbaum, Robert L., et al. Thompson & Thompson genetics in medicine, 8th ed.. Elsevier Health Sciences, 2016.

Strachan, Tom. Genetics and genomics in medicine. Taylor & Francis, 2014.

Lewis, Ricki. Human genetics: the basics. Garland Science, 2016.

Cavalli-Sforza, Luigi Luca, et al. The history and geography of human genes. Princeton university press, 1994.

Cavalli-Sforza, Luigi Luca, and Walter Fred Bodmer. The genetics of human populations. Courier Corporation, 1999.

Saitou, Naruya. Introduction to evolutionary genomics. London: Springer, 2013.

Hartl, Daniel L.,  and Andrew G. Clark. Principles of population genetics. Vol. 116. Sunderland, MA: Sinauer associates, 1997.

Syllabus

Last update: Kateřina Esserová, DiS. (11.06.2019)

The course will cover following topics:

Organization and inheritance of the human genome

Human genom variation and diversity

Origins of modern humans, connection to apes and genetic changes that have made us human

Distribution of genetic diversity in modern populations (migrations, admixture)

Agriculture - origins, population effects, diseases

Evolutionary insights into simple and comples genetic diseases

Course completion requirements

Last update: Kateřina Esserová, DiS. (11.06.2019)

Students are oblidged to handle in an essay and pass an oral exam. Topic and length of the essay will be discussed at the first lecture.