Subjects

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Study of Structure and Dynamics of Macromolecular Systems - NFPL041

Title:	Studium struktury a dynamiky makromolekulárních systémů
Guaranteed by:	Department of Condensed Matter Physics (32-KFKL)
Faculty:	Faculty of Mathematics and Physics
Actual:	from 2004 to 2021
Semester:	summer
E-Credits:	3
Hours per week, examination:	summer s.:2/0, Ex [HT]
Capacity:	unlimited
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
State of the course:	taught
Language:	Czech
Teaching methods:	full-time
Teaching methods:	full-time

Guarantor:	RNDr. Jindřich Hašek, DrSc.

Opinion survey results Examination dates Schedule Noticeboard

Annotation -

Last update: Mgr. Kateřina Mikšová (10.06.2022)

The course is a free continuation of lectures about X-ray diffraction and describes basic principles used for determination of molecular structure. It elucidates challenges of protein crystallography and time-resolved crystallography, which opened new areas in investigation of structure and function of bio-macromolecules. The course shows different usages of the synchrotron radiation sources and slow neutron sources for determination of molecular structures in atomic resolution. It is accompanied by examples of measurement and by applications of the methods for elucidation of function of biological systems and for design of new drugs

Syllabus -

Last update: Mgr. Kateřina Mikšová (10.06.2022)

Introduction to the problems of molecular biology

Preparation of materials for research

Diffraction on crystalline materials

Diffractometers

Phase problem solution

Real-time experiments

Neutron diffraction

Practical applications of synchrotron radiation