Subjects

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Interactions of proteins and membrane - introduction to soft matter - NBCM147

Title:	Interakce proteinů a membrán - úvod do soft matter
Guaranteed by:	Department of Chemical Physics and Optics (32-KCHFO)
Faculty:	Faculty of Mathematics and Physics
Actual:	from 2013
Semester:	winter
E-Credits:	5
Hours per week, examination:	winter s.:2/1, C+Ex [HT]
Capacity:	unlimited
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
State of the course:	taught
Language:	Czech
Teaching methods:	full-time
Teaching methods:	full-time

Guarantor:	RNDr. Robert Vácha, Ph.D.

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Annotation -

Last update: T_KCHFO (15.04.2013)

The course is focused on basic knowledge of interactions of proteins and membranes at coarse-grained level. It covers also development of appropriate soft matter models, their approximations and limitations. At the end, few advanced methods of Monte Carlo simulations that are often used in this field are described.

Literature -

Last update: T_KCHFO (15.04.2013)

Intermolecular and Surface Forces 3rd edition by Jacob N. Israelachvili; Academic Press 2010

Giant Molecules: Here, There, and Everywhere 2nd edition by Alexander Y. Grosberg et al.; World Scientific Press 2010

Soft Condensed Matter Physics in Molecular and Cell Biology by W.C.K. Poon and D. Andelman; Taylor & Francis 2006

Syllabus -

Last update: T_KCHFO (15.04.2013)

1. Introduction to soft matter

2. Ideal chain approximation

3. Ideal thin membrane

4. Interaction of uncharged membranes and proteins

5. Interaction of charged membranes and proteins

6. Towards realistic interactions of membranes and proteins

7. Thermodynamic principles of self-assembly

8. Langmuir adsorption

9. Transport phenomena

10. Advanced Monte Carlo