Practical Organic Chemistry - MC270C93

• Title: Practical Organic Chemistry
• Guaranteed by: Department of Organic Chemistry (31-270)
• Faculty: Faculty of Science
• Actual: from 2021 to 2021
• Semester: both
• E-Credits: 4
• Hours per week, examination: 0/2, C [TS]
• Capacity: unlimited
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Explanation: The beginning of the laboratory course is in front of laboratory no. 145 at theDepartment of Organic Chemistry at 9:00. Compulsory laboratory coat, safetyglasses and closed shoes.
• Note: enabled for web enrollment; you can enroll for the course in winter and in summer semester
• Guarantor: Mgr. Michal Urban, Ph.D.
• Teacher(s): Mgr. Michal Urban, Ph.D.
• Class: Mikrovlnný reaktor; Kompaktní preparativní system; Mikrodestilační přístroj; Odparka a membránová jednotka; Původní předmět
• Incompatibility : MC270C92
• Is incompatible with: MC270C92

Annotation

Last update: Mgr. Michal Urban, Ph.D. (08.09.2023)

The basic practice of organic chemistry have the task to teach students the basics of laboratory techniques
and methodology of work in the organic laboratory.
Synthetic tasks are chosen so that the students are acquainted with basic chemical operations, and to obtain information
on the preparation and properties of organic compounds.
Students thus have to supplement the theoretical knowledge from the lectures of organic chemistry.

Literature

Last update: Mgr. Michal Urban, Ph.D. (17.02.2022)

Zubrick J.W. : Organic Lab Survial Manual: A Student's Guide to Techniques. 9th edition, John Wiley and Sons: New York 2015

J. R. Mohring, D. G. Alberg, G. E. Hofmeister, P. F. Schatz, Ch. Noring Hammond: Laboratory Techniques in Organic Chemistry. W. H. 4^th edition, Freeman and Company: 2014

Ch. F. Wilcox, Jr.: Experimental Organic chemistry – Theory and Practice. MacMillan Publishing Company 1984.

 

Requirements to the exam

Last update: Mgr. Michal Urban, Ph.D. (19.01.2024)

During the laboratory course, prepare 8 compounds according to the instructions in the scripts.
Submit prepared compounds with laboratory protocols.

It is necessary to get 60% of the final test

Syllabus

Last update: Mgr. Michal Urban, Ph.D. (31.08.2021)

The basic practice of organic chemistry have the task to teach students the basics of laboratory techniques
and methodology of work in the organic laboratory.
Synthetic tasks are chosen so that the students are acquainted with basic chemical operations, and to obtain information
on the preparation and properties of organic compounds.
Students thus have to supplement the theoretical knowledge from the lectures of organic chemistry.

Filling the practice :
1. Basic operations in the organic laboratory: procedures of isolation organic substances; cleaning
operations; monitoring the progress of reactions; chromatographic methods
2. Work safety and first aid in the organic laboratory.
3. Laboratory technique : the construction of the apparatus for chemical reaction; mixing;
heating; cooling; work under reduced pressure in an inert atmosphere, and if protected
from humidity
4. Cleaning and isolation procedures : filtration; washing; extraction; drying
of solids and liquids; crystallization
5. Distillation : simple distillation; distillation under reduced pressure; mastering the work
with the rotary vacuum evaporator
6. Thin layer chromatography .
7. The leadership of the working of the protocol.

Předmět byl inovován v rámci projektu ESF pro VŠ II na UK, reg. č.: CZ.02.2.69/0.0/0.0/18_056/0013322

The course was innovated within the ESF project for HE II at Charles University, reg. no.: CZ.02.2.69/0.0/0.0/18_056/0013322

Entry requirements

Last update: Mgr. Michal Urban, Ph.D. (19.01.2024)

For the entrance test:

The test is focused on laboratory safety, properties of organic solvents, recognition of chemical glassware, and theoretical knowledge of proper laboratory work. 

For the Czech students:

It is necessary to study pages 9-121 from the book

Veselý J.; Machara A. : Příručka laboratorní organické chemie , skripta UK , Praha 2020

For Erasmus students:

J. R. Mohring, D. G. Alberg, G. E. Hofmeister, P. F. Schatz, Ch. Noring Hammond: Laboratory Techniques in Organic Chemistry. W. H. 4^th edition, Freeman and Company: 2014

It is necessary to get 60% of the entrance test