SubjectsSubjects(version: 945)
Course, academic year 2023/2024
   Login via CAS
Techniques of NMR spectroscopy - MC260P107
Title: Techniky NMR spektroskopie
Czech title: Techniky NMR spektroskopie
Guaranteed by: Department of Physical and Macromolecular Chemistry (31-260)
Faculty: Faculty of Science
Actual: from 2019
Semester: summer
E-Credits: 4
Examination process: summer s.:
Hours per week, examination: summer s.:3/0, Ex [HT]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Note: enabled for web enrollment
Guarantor: RNDr. Zdeněk Tošner, Ph.D.
Teacher(s): RNDr. Zdeněk Tošner, Ph.D.
Is incompatible with: MC260P18
Is interchangeable with: MC260P18
Annotation -
Last update: KFNTZT/MFF.CUNI.CZ (06.06.2019)
The course will introduce modern theory of NMR spectroscopy and its pulsed experimental techniques with application to liquid samples. Besides interpretation of one- and two-dimensional NMR spectra for resonance assignment and structural information, additional techniques will be discussed that allow to follow dynamic processes like motion, conformational changes and complex formation.
Literature -
Last update: KFNTZT/MFF.CUNI.CZ (06.06.2019)

Hore, P.J., Jones, J.A.; Wimperis, S.: NMR: the toolkit, Oxford University Press, 2000.

Hore, P.J.: Nuclear magnetic resonance, Oxford University Press, 1995.

Claridge, T.D.W.: High-resolution NMR techniques in organic chemistry, Elsevier, 2009.

Levit, M.H.: Spin Dynamics, John Wiley & Sons, 2008.

Requirements to the exam -
Last update: KFNTZT/MFF.CUNI.CZ (06.06.2019)

Exam will consist of presenting solution of a homework project. The project is assigned at least 14 days prior examination and tests understanding principles of pulse experiments and spectra information content.

Syllabus -
Last update: KFNTZT/MFF.CUNI.CZ (06.06.2019)

1.      NMR phenomenon, NMR spectrum, NMR spectrometer.

2.      Vector model and modern description of NMR, rotations and product operators.

3.      NMR interactions and their manifestation n NMR spectra, interpretation of 1D spectra.

4.      Polarization transfer, two-dimensional spectroscopy, experiments COSY, TOCSY, HSQC, HMQC, HMBC.

5.      Spin relaxation, nuclear Overhauser effect, experiments IR, CPMG, NOESY, ROESY.

6.      Chemical exchange. Translational diffusion.

7.      Intermolecular interactions, chemical kinetics and stability constants, interpretation of relaxation.

8.      Basics on solid-state NMR.

Registration requirements -
Last update: KFNTZT/MFF.CUNI.CZ (06.06.2019)

Contact the lecturer at the beginning of semester for actual schedule.

 
Charles University | Information system of Charles University | http://www.cuni.cz/UKEN-329.html