Subjects

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Advanced Organic Chemistry - GAF229

Title:	Advanced Organic Chemistry
Guaranteed by:	Department of Organic And Bioorganic Chemistry (16-16120)
Faculty:	Faculty of Pharmacy in Hradec Králové
Actual:	from 2022
Semester:	winter
Points:	0
E-Credits:	3
Examination process:	winter s.:combined
Hours per week, examination:	winter s.:0/42, C+Ex [HS]
Capacity:	unknown / unlimited (26)
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
Key competences:
State of the course:	taught
Language:	English
Teaching methods:	full-time
Teaching methods:	full-time
Level:
Explanation:	(F 3.r.)
Note:	deregister from the exam date if a requisite was not fulfilled course can be enrolled in outside the study plan enabled for web enrollment

Guarantor:	prof. RNDr. Milan Pour, Ph.D.
Co-requisite :	GAF299
In complex pre-requisite:	GAF1002

Examination dates WS schedule

Annotation -

Last update: prof. RNDr. Milan Pour, Ph.D. (02.10.2023)

The subject follows up on Organic Chemistry I and II, and aims at expanding the knowledge of modern Organic Chemistry with a focus on the methods of rational design, practical synthesis and structural analysis of biologically active compounds. Topics: Modern methods of organic synthesis, Molecular modelling, Advanced structural analysis.

Course completion requirements -

Last update: prof. RNDr. Milan Pour, Ph.D. (02.10.2023)

The subject is terminated by a credit and a written exam. In order to obtain the credit, 100% attendance at seminars is required.

Literature -

Last update: prof. RNDr. Milan Pour, Ph.D. (02.10.2023)

Obligatory:

null. . In Carey, Francis A., Sundberg, Richard J.. Advanced organic chemistry . New York: Kluwer Academic ; Plenum Publishers, 2000, s. -. ISBN ..

Syllabus -

Last update: prof. RNDr. Milan Pour, Ph.D. (02.10.2023)

Modern methods of organic synthesis

Retrosynthetic analysis
Basic principles of stereoselective synthesis
Protective groups
Catalytic reactions: metal catalysis, organocatalysis
Pericyclic reactions
Advances in heterocyclic synthesis

Molecular modelling

Introduction to molecular modelling

Advanced methods of structural analysis

Advanced techniques of NMR and MS