Pathological physiology is a preclinical subject that deals with etiology (causes) and pathogenesis (development) of body dysfunctions. It aims to understanding of mechanisms that can influence the origin and course of diseases, which is necessary for correct causal and individualized treatment. In the first term students are taught general principles of diseases and their effect on organism. A part of the study is devoted to states that accompany the specific diseases e.g. effects of inflammation, hypoxia, and internal environment disorders. Further students gain a comprehensive overview of etiology and pathogenesis of blood, cardiovascular and respiratory diseases. Practical part of the study is oriented mainly to acquiring knowledge of registration and description of ECG. In Computer spirometry practical class the students get information about most frequent spirometry findings in respiratory diseases.
Entry requirements
Last update: Lenka Kořínková (14.09.2023)
prerequisites – compulsory subjects of 1st year GM, Biology II, Biochemistry II, Physiology II.
Aim of the course
Last update: Lenka Kořínková (14.09.2023)
1. ability to explain general principles and consequences of impaired body functions
2. knowledge of pathophysiology of cardiovascular, respiratory and blood diseases
3. description of basic parameters of ECG and distinguishing pathological from physiological findings
4. distinguishing normal spirometry recording from findings typical for obstructive and restrictive respiratory disorders
Requirements to the exam
Last update: Lenka Kořínková (14.09.2023)
Credit:
a) presence in practical classes/seminars
- mandatory 100% participation, tolerance of a maximum of one excused absence
- in case of more than one absence it is necessary to replace the seminar/practical class (the way of a replacement is determined by the teacher of the particular seminar/practical class, usually it is oral examination of the issue)
b)tests
description of two ECG curves when each must be evaluated with the worst grade 3 (in the range 1(excellent) – 4 (fail))
passing all the ongoing tests with the worst grade 3
- in case of non-participation, an apology before the time of the test is required and the test must be taken on an alternative date
- student is allowed to one excuse during the whole year
- non-excused absence is evaluated wit grade 4
Possibility of consultations after previous agreement with teachers of Department of Pathological Physiology
Syllabus
Last update: Lenka Kořínková (14.09.2023)
Lectures
Lecturers
prof. MUDr. Miroslav Kuba, DSc.
prof. MUDr. Zuzana Kubová, CSc.
MUDr. Marie Chutná
MUDr. Lenka Miščík Ramešová
Organism and Environment, Adaptation. Etiology and Pathogenesis. Health Versus Disease. Clinical and Biological /Somatic/Death. (Kuba)
Alterations in Fluid Volume. Disorders of Osmolarity, Etiology and Pathogenesis of Oedema. Hyponatremia, Hypernatremia. (Kubová)
