SubjectsSubjects(version: 945)
Course, academic year 2014/2015
   Login via CAS
Pharmacology II - FG10036
Title: Farmakologie II
Guaranteed by: Department of Pharmacology (15-310)
Faculty: Faculty of Medicine in Hradec Králové
Actual: from 2011 to 2016
Semester: winter
Points: 0
E-Credits: 4
Examination process: winter s.:
Hours per week, examination: winter s.:25/36, C+Ex [HS]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Level:  
Note: deregister from the exam date if a requisite was not fulfilled
Guarantor: prof. MUDr. Stanislav Mičuda, Ph.D.
Incompatibility : FV10034
Pre-requisite : FG10028
Interchangeability : FA0107041, FV10034
Is incompatible with: FV10034
Is interchangeable with: FV10034
In complex pre-requisite: FG10076, FG10077, FG10078, FG10079, FG10080
Examination dates   Schedule   
Annotation
Last update: Hana Kalhousová (09.09.2015)
Teaching fluently follows the Pharmacology I lessons and will be focused on the special chapters organized to topics according particular organ systems and to drug prescription.
Requirements to the exam
Last update: Hana Kalhousová (09.09.2015)

Credit:

The attendance on practical classes is compulsory (only one absence is acceptable). The average from all classifications in the term (semester) must be below or equal to 3.00 In the case of failure to meet the conditions for the credit: The case of two absences - the student will be examined in depth from the topics of both practical classes on which the student was absent. The case of three or more absences - the student will be examined from the topics covering the whole term (semester). The case of the average grading > 3.00 - the student will be examined from the topics covering the whole term (semester).

Examination:

Only students with the credits from both semesters (winter and summer) written in their indexes are eligible for the final exam. Final exam consists of MCQ test and oral examination. Those students who have the average classification grading in both semesters below or equal 2.00 (considered separately) are allowed to omit the MCQ test and enter directly the oral part of the examination. Even in the case of failure in the written part of the exam, the student can pass forward to the oral part of the examination; however, this result will be reflected in the final classification. The results of the written part of the examination are included in the final classification grading (if applicable). Further details to the organisation of the final examinations will be given in advance on the Department’s board.

 

 

Syllabus
Last update: Hana Kalhousová (09.09.2015)

Lectures

Lecturers

  • Prof. Vladimír Geršl, M.D., Ph.D.
  • Assoc. Prof. Stanislav Mičuda, M.D., Ph.D.
  • Assoc. Prof. Martin Štěrba, PharmD., Ph.D
  • Assoc. Prof. Jaroslav Chládek, MSc., Ph.D.
  1. Histamine, antihistamines. Drugs affecting hemostasis. (Chládek, 3)
  2. Antiarrhythmic drugs, cardiac glycosides, drugs affecting RAAS. (Štěrba, 3)
  3. Vasodilators,  diuretics, drugs in treatment of hypertension, ischemic heart disease. (Štěrba, 3)
  4. Drugs in treatment heart failure. Hormones - insulin. (Geršl, 3)
  5. Hormones - oral antidiabetics, corticosteroid hormones. (Geršl, 3)
  6. Hormones - glucocorticoids, sexual hormones. (Geršl,2)
  7. Antibacterial drugs - general pharm., beta-lactams, vankomycine. (Mičuda, 2)
  8. Antibacterial drugs - tetracyclines, macrolides, aminoglycosides. (Mičuda, 2)
  9. Antibacterial drugs - sulfonamides, quinolones, other ATB and overview of use of ATB. (Mičuda, 2)
  10. Antitubercular drugs, anticancer drugs - general pharmacology. (Chládek, 2)

 

Practical courses & seminars

Lecturers

  • Assoc. Prof. Stanislav Mičuda, M.D., Ph.D.
  • Assoc. Prof. Martin Štěrba, PharmD., Ph.D.
  • Assoc. Prof. Jaroslav Chládek, MSc., Ph.D.
  • Jolana Cermanová, M.D., Ph.D.
  • Olga Lenčová, PharmD., Ph.D.
  1. Drug dependence and abuse, revision of CNS pharmacology - microlesson and seminar. General pharmacology of drug dependence, drugs and agents inducing dependence. Revision of CNS affecting drugs related to the topics (esp. hypnosedatives and opioids). Test.
  2. Antiasthmatics, histamin and antihistamines - microlesson and seminar. Basic and clinical pharmacology. Approach to asthma management. Practical demonstrations: Handling different types of inhalers. Test.
  3. Drugs used in altered states of hemostasis (bleeding and thrombosis) - seminar. Basic and clinical pharmacology. Therapy of thrombosis and monitoring of therapy with anticoagulants. Case reports. Test.
  4. Cardiac glycosides, drugs affecting RAAS, diuretics - seminar. Basic and clinical pharmacology.Test.
  5. Vasodilators, agents used in cardiac arrhythmias, pharmacological treatment of angina, hypertension and heart failure - seminar. Basic and clinical pharmacology. Test.
  6. Drugs acting on the gastrointestinal tract. Hypolipidemic drugs - microlesson and seminar. Test.
  7. Pharmacology of hormones - insulin and antidiabetics, corticoids - microlesson and seminar. Test.
  8. Antibiotics I - seminar. Beta-lactams, aminoglykosides, glycopeptides, clindamycin, chloramphenicol, macrolides Case reports: Nephrotoxicity of aminoglycosides. Demonstrations: TDM of antibiotics (aminoglycosides, vancomycin). Aminoglycosides OD. Test.
  9. Antibiotics II - seminar. Quinolones, sulphonamides, urinary tract antiseptics, antimycobacterial and antifugal drugs. Test.
  10. Anticancer chemotherapy - microlesson and seminar. Basic pharmacology of cytostatics. Test.
  11. Factors influencing the response to a drug. a. depending on the drug: physico-chemical features, route of administration, drug formulation, food; b. depending both on the drug and on the body: dose, repeated administration (accumulation, tolerance), coadministration with other drugs (synergism, antagonism), delayed effects; c. depending on the body: gender, age, genetic information, pathological state. Demonstration: digoxin and lignocaine in kidney and liver failure. Test.
  12. Basic information on pharmaceutical dosage forms, prescription writing - microlesson and seminar. Test and credit.

Notes:

1) Students are supposed to be theoretically prepared on each practical lesson/seminar and the understanding to the topic will be regularly examined (MCQ tests/written tests/oral examination). 

Literature
Last update: Hana Kalhousová (09.09.2015)

 

Compulsory literature

  1. Katzung BG, Masters SB, Trevor AJ: Basic and Clinical pharmacology, 11th ed., McGrawHill Lange, 2009. ISBN 978-0-07-160405-5

Recommend literature

  1. Rang HP, Dale MM, Ritter JM: Pharmacology. 6th ed., Churchill Livingstone, 2007. Standard ed. ISBN 00443069115
  2. Harvey RA: Lippincott´s Illustrated Reviews: Pharmacology, 2012, 5th ed., Lippincott Williams and Wilkins, ISBN 1451113145

Completive literature

  1. Lectures in electronic form (https://moodle.lfhk.cuni.cz/)
 
Charles University | Information system of Charles University | http://www.cuni.cz/UKEN-329.html