Medical Immunology I - FG10018

• Title: Základy lékařské imunologie I
• Guaranteed by: Department of Clinical Immunology and Allergology (15-630)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2014 to 2015
• Semester: summer
• Points: 0
• E-Credits: 2
• Examination process: summer s.:
• Hours per week, examination: summer s.:14/9, C [HS]
• Capacity: unlimited
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Guarantor: prof. RNDr. Jan Krejsek, CSc.
• Incompatibility : FV10016
• Interchangeability : FA0104100, FV10016
• Is incompatible with: FV10016
• Is pre-requisite for: FG10033
• Is interchangeable with: FV10016
• In complex pre-requisite: FG10076, FG10077, FG10078, FG10079, FG10080

Annotation

Last update: VALESOVAA (20.01.2015)

Homeostasis, danger signals, safe signals, pattern recognition, inflammation, alarmins, inflammasome, signalisome, innate immunity, antigen processing and presentation, specific immunity, humoral specific immunity, regulatory subsets of T cells, skin immunity, mucosal immunity, probiotics, prebiotics, immunopathology, immunodeficiencies, primary, acquired, HIV infection and AIDS, immunomodulation, biological therapy, active immunisation.

Requirements to the exam

Last update: VALESOVAA (20.01.2015)

Credit

Active participation in practicals. Final multiple choice test passing.

Examination

Oral examination.

Syllabus

Last update: VALESOVAA (20.01.2015)

Lecturers

Lectures

• Prof. Dr. Jan Krejsek, M.Sc., Ph.D.
• Assoc. Prof. Dr. Ctirad Andrys, Ph.D. 

Theme

1. Cells and organs of immune system, basic principals of immune regulations. (Krejsek)
2. Innate immunity as a fundament of protection, danger (damage) signals, PRR receptors. Complement system and phagocytosis, regulation and effector mechanisms of innate immunity. (Andrýs)
3. HLA system, antigen processing, T cells and their regulatory subsets. B cells, regulation of antibodies synthesis. (Andrýs)
4. Skin and mucosal protection mechanisms, role of physiological gut microflora. (Krejsek)
5. Inflammation, protective and immunopathological mechanisms. (Andrýs)

Practical courses & seminars

Lecturers

• Prof. Dr. Jan Krejsek, M.Sc., Ph.D.
• Assoc. Prof. Dr. Ctirad Andrys, Ph.D.

Practical courses

1. Indication and interpretation of laboratory tests in clinical immunology.
2. Autoantibodies in the diagnosis of immunopathological diseases.
3. Allergic inflammation, pathogenesis, principles of laboratory and clinical detection.

Literature

Last update: VALESOVAA (20.01.2015)

Compulsory literature

1. Abbas textbook Cellular and Molecular Immunology in electronic form is available in our Library as the best source to prepare to exam.

Recommended literature

1. Murphy KM, Travers P, Walport M, Janeway´s Immunobiology (8th edition or the last edition) Garland Science, 2012 ISBN 978-0-8153-4243-4
2. It is highly recommended to follow IT MEDIK which is the newest material available. It is in Czech, however, there are many self explaining schemes there.