Molecular Medicine - FDP064

• Title: Molecular Medicine
• Guaranteed by: Department of Medical Biology and Genetics (15-120)
• Faculty: Faculty of Medicine in Hradec Králové
• Actual: from 2023
• Semester: winter
• Points: 0
• E-Credits: 1
• Examination process: winter s.:
• Hours per week, examination: winter s.:9/3, C [HS]
• Capacity: unlimited
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Guarantor: doc. RNDr. Věra Králová, Ph.D.
• Pre-requisite : {Compulsory subjects 3rd year Dentistry (2019->)}
• Incompatibility : FZ10065
• Interchangeability : FA0209137, FZ10065
• In complex pre-requisite: FDP079

Annotation

Last update: Marcela Laláková (17.09.2023)

Genomics in medicine – human genome, methods of gene mapping, genomics, transcriptomics, proteomics, translation of genomic data into clinical practice. Gene therapy – theoretical concepts, current clinical applications. Non-coding RNAs – functions, emerging medical significance. Biological therapy of tumours. Epigenetic mechanisms in the control of gene expression.

Requirements to the exam

Last update: Marcela Laláková (17.09.2023)

REQUIREMENTS FOR CREDIT

For credit, student should have attendance in seminars and pass a credit test.

Syllabus

Last update: Marcela Laláková (17.09.2023)

Practical courses & seminars

Lecturers:

• Doc.RNDr. Vera Kralova, Ph.D.
• Prof. PharmDr. Emil Rudolf, Ph.D.
• RNDr. Jana Nekvindová, Ph.D.

Seminars

1. 11.	Genomics and the search for genes responsible for diseases. Gene therapy.	Králová
8. 11.	Genetic heterogeneity of tumors.	Rudolf
15. 11.	Clinical applications of molecular genetic methods.	Nekvindová
22. 11.	Practical class: Clinical applications of molecular genetic methods – molecular genetic laboratories of the Derpartment of Clinical Biochemistry and Diagnostics, University Hospital.	Nekvindová

Literature

Last update: Marcela Laláková (17.09.2023)

Recommend literature

1. J. Pongracz, M. Keen Medical Biotechnology, Elsevier, 2009, ISBN 978-0-08-045135-0
2. Internet - based on-line databases Medline and PubMed