Subjects

Your browser does not support JavaScript, or its support is disabled. Some features may not be available.

Biobanking for biomarker assessment and their benefits for patients - EAV32101

Title:	Biobanking for biomarker assessment and their benefits for patients
Guaranteed by:	Centrální laboratoř pro imunoanalýzu (14-321)
Faculty:	Faculty of Medicine in Pilsen
Actual:	from 2023
Semester:	both
Points:	4
E-Credits:	4
Examination process:
Hours per week, examination:	0/26, C [HS]
Capacity:	winter:unknown / unknown (25) summer:unknown / unknown (25)
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
Key competences:
State of the course:	cancelled
Language:	English
Teaching methods:	distance
Teaching methods:	distance
Level:
For type:
Note:	course can be enrolled in outside the study plan you can enroll for the course in winter and in summer semester

Guarantor:	RNDr. Marie Karlíková, Ph.D. prof. PharmDr. Radek Kučera, Ph.D. prof. MUDr. Ondřej Topolčan, CSc.
Comes under:	Volitelné předměty, 4. ročník Všeobecné

Opinion survey results Examination dates Schedule Noticeboard

Annotation -

Last update: Ing. Lenka Křikavová (02.09.2021)

The course is focused on the use of biomarkers in personalized (precision) medicine (medicine "tailored" to the patient),
on methods of their determination and the importance of storing and sharing biological samples in biobanks for
biomarker research. The course content interconnects several disciplines, such as laboratory diagnostics, pathology
and biostatistics, and emphasizes the practical use of this "symbiosis" for clinical decision-making and therefore the
benefit of the patient, but also for biomedical research.
The course is organized in cooperation with the Department of Pathology and Biobank of the partner University of
Regensburg. with students of the partner university, and includes practical lab exercises both in Pilsen and Regensburg.

Aim of the course -

Last update: Ing. Lenka Křikavová (02.09.2021)

Introduction to the role of banks of biological material (or biobanks) in personalized medicine, especially for research and use of biomarkers in clinical practice

Course completion requirements -

Last update: Ing. Lenka Křikavová (02.09.2021)

Test + short individual work

Literature -

Last update: Ing. Lenka Křikavová (18.05.2021)

Povinná literatura:
Kinkorová J. Biobanks - present and future (online .)

Karlíková M. Biomarkers in oncology (online .)

Pecen L. Personalised medicine and statistics (online .)

Doporučená literatura:
Fuchsová R. Biomarkers in the prostate carcinoma diagnostics (online .)

Teaching methods -

Last update: Ing. Lenka Křikavová (02.09.2021)

Distance (e-learning + on-line seminar) + internship

Requirements to the exam - Czech

Last update: Mgr. Martina Buriánková (04.10.2021)

Participation + test + short writting work

Syllabus -

Last update: Ing. Lenka Křikavová (02.09.2021)

1. Biobanks and their role in medicine

1.1 Introduction - definition, structure and function of biobanks

1.2 Clinical issues of biobanking

1.3 Roles of biobanks in comprehensive cancer centres

2. Precision medicine

2.1 The concept of precision medicine

2.2 Spin off companies and personalised medicine

3. Biomarkers

3.1 Circulating biomarkers - research and clinical use

3.2 Indications and interpretation of biomarkers in oncology

3.3 Statistical methods for evaluation of biomarkers

4. Laboratory techniques

4.1 Liquid biobanking

4.2 Immunoanalytical methods

4.3 Tissue handling

4.4 Combination of laboratory and pathological methods - prostate cancer management

5. Experience with biobanks

Practical exercises in the Department of Immunochemical Diagnostics and Biobank of the University Hospital Pilsen and the Institute of Pathology and Biobank of the University of Regensburg

The abstracts of lectures are online at https://oid.fnplzen.cz/node/2089

Course completion requirements -

Last update: Ing. Lenka Křikavová (02.09.2021)

Test + short individual work