Pharmacology I. - EAP0102100

• Title: Pharmacology I.
• Guaranteed by: Ústav farmakologie (14-100)
• Faculty: Faculty of Medicine in Pilsen
• Actual: from 2023
• Semester: summer
• Points: 3
• E-Credits: 3
• Examination process: summer s.:
• Hours per week, examination: summer s.:3/3, C [HT]
• Capacity: unlimited / unlimited (unknown)
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Note: deregister from the credit exam date if a requisite was not fulfilled
• Guarantor: prof. PharmDr. Radek Kučera, Ph.D.
• Teacher(s): PharmDr. Bc. Eva Dědečková; prof. PharmDr. Radek Kučera, Ph.D.
• Attributes: Povinné předměty pro Všeobecné lékařství
• Incompatibility : EA0106015
• Pre-requisite : EAP0101030
• Interchangeability : EA0106015
• Is pre-requisite for: EAP0103100
• Is interchangeable with: EA0106015

Annotation

Last update: PharmDr. Bc. Eva Dědečková (27.09.2021)

Pharmacology is a preclinical subject, in which students acquire knowledge of basic principles of pharmacodynamics, pharmacokinetics and mechanism of action of individual drugs.
Rational pharmacotherapy taught during seminars focuses on suitable individual drug choice for each patient and avoiding drug interaction or adverse effects. Students also get familiar with the fundamentals of drug prescription in a theoretical and practical way.

Course completion requirements

Last update: PharmDr. Bc. Eva Dědečková (27.09.2021)

Attendance at seminars is mandatory. Active participation in seminars, independent home preparation and elaboration of assigned tasks, completion of progress tests, and a final credit test are required for the credit to be awarded. The student can obtain credit in pharmacology in one regular and two corrective terms at the end of the semester.

Literature

Last update: PharmDr. Bc. Eva Dědečková (27.09.2021)

• Rang-Dale-Ritter: Pharmacology - 7^th Edit., (Churchill - Livingstone).
• Lippincott Illustrated Reviews - 7^th International Edition
• Dale - Haylett: Pharmacology Condensed, (Churchill - Livingstone)
• A.J.Trevor, B.G.Katzung, S.B.Masters: Katzung and Trevor's Pharmacology  McGraw - Hill
• British National Formulary (latest edition)

Syllabus

Last update: PharmDr. Bc. Eva Dědečková (02.02.2022)

LECTURES:

1.      Pharmacodynamics

2.      Pharmacokinetics I.

3.      Pharmacokinetics II.

4.      Pharmacokinetics III.

5.      Pharmacokinetic basis of drug dosing, single and repeated drug administration.

6.      Individualization of pharmacotherapy: pharmacogenetics, gene therapy. Biological treatment.

7.      Vegetative nervous system - sympathetic

8.      Vegetative nervous system - parasympathetic.

9.      Chemical mediators.

10.     Antiepileptic drugs.

11.     Psychiatric drugs I.

12.     Psychiatric drugs II.

13.     Central and peripheral muscle relaxants. General and local anesthetics.

14.     Infusion therapy, enteral and parenteral nutrition.

 

SEMINARS:

1. Introduction to pharmacology. Pharmacopeias. Regulatory authorities.

2. General principles of drug prescribing. Prescribing an RMP.

3. Basics of IPP prescriptions. Routes of drug administration. Introduction to dosage forms.

4. Liquid DF. Dispersions, semi-solid DF. Prescription of IPP in otorhinolaryngology and ophthalmology. Dermatologics.

5. Solid dosage forms, 2nd, and 3rd generation of DF. Incompatibilities.

6. Drug research and development.

7. Pharmacovigilance. Drug allergy, anaphylactic shock.

8. Drugs in specific periods of life. Carcinogenic and mutagenic effects.

9. Pharmacokinetics - repetition.

10. Parkinson's, Alzheimer's disease. Nootropics.

11. Treatment of pain.

12. Treatment of migraine.

13. Total repetition.

14. Credit test

Course completion requirements

Last update: PharmDr. Bc. Eva Dědečková (27.09.2021)

Attendance at seminars is mandatory. Active participation in seminars, independent home preparation and elaboration of assigned tasks, completion of progress tests, and a final credit test are required for the credit to be awarded. The student can obtain credit in pharmacology in one regular and two corrective terms at the end of the semester.