Pharmacology I - EA0106015

• Title: Farmakologie I
• Guaranteed by: Ústav farmakologie (14-100)
• Faculty: Faculty of Medicine in Pilsen
• Actual: from 2021
• Semester: summer
• Points: 3
• E-Credits: 3
• Examination process: summer s.:
• Hours per week, examination: summer s.:2/2, C [HT]
• Capacity: unknown / unknown (unknown)
• Min. number of students: unlimited
• 4EU+: no
• Virtual mobility / capacity: no
• State of the course: not taught
• Language: English
• Teaching methods: full-time
• Teaching methods: full-time
• Guarantor: prof. PharmDr. Radek Kučera, Ph.D.
• Co-requisite : EA0104011, EA0104137, EA0104510
• Interchangeability : EAP0102100
• Is co-requisite for: EA0108120, EA0107033, EA0107041
• Is incompatible with: EAP0102100
• Is interchangeable with: EAP0102100

Annotation

English

Last update: BURIANKO (26.04.2005)

Pharmacokinetics/dynamics, individ. variation, side effects, interactions, evaluation of new drugs, rational pharmacother., pharmacopoeia, drug formulations, prescribing of drugschemical mediators, nervous system, drugs affecting heart + vascular system, haemostasis + thrombosis, diuretics, dislipoproteinaemias, respiratory + gastrointestinal systems, uterus, anti-inflammatory + immunosuppressant drugs, radiopharmaceuticals, locally acting drugs, disinfectant +antiseptic agents, chemotherapy of infectious + malignant disease, hormones, vitamins, toxicology, phytotherapy, phytotoxicology

Czech

Last update: BURIANKO (26.04.2005)

Farmakokinetika, farmakodynamika, individuální variabilita, nežádoucí účinky, interakce, hodnocení nových léčiv, účelná farmakoterapie, lékopis, lékové formy ,základy recepturychemické mediátory, nervový systém, látky ovlivňující cévy a srdce, hemostáza, tromboza, diuretika, dislipoproteinémie, dýchací a trávicí ústrojí, uterotonika a tokolytika, antiflogistika a imunosupresiva, rtg kontrastní látky, radiofarmaka, lokálně působící látky, desinficiencia, antiseptika, chemoterapie infekčních a nádorových onemocnění, hormony, vitaminy, základy toxikologie, fytoterapie, fytotoxikologie

Literature

Last update: Irena Zemenová (11.10.2010)

GENERAL PRINCIPLES OF PHARMACOLOGY

1. Rang-Dale-Ritter: Pharmacology - 6^th Edit., (Churchill - Livingstone).

2. Dale - Haylett: Pharmacology Condensed, (Churchill - Livingstone)

3. British National Formulary (latest edition)

 

Special pharmacology

1. H.P.Rang, M.M.Dale, P.K.Moore: Pharmacology (Churchill Livingstone)

2. M.M.Dale, D.G. Haylett: Pharmacology condensed (Churchill Livingstone)

3. A.J.Trevor, B.G.Katzung, S.B.Masters: Katzung and Trevor?s Pharmacology  McGraw - Hill

Requirements to the exam

Last update: Irena Zemenová (22.05.2018)

Credit requirements:

 

Attendance at seminars, passing two interim tests, oral presentation covering latest news in pharmacy and therapeutics, submission of computer simulated experiments report

and passing a credit test (covering the materials from the seminars) are compulsory. There is one regular date and two resit dates for the credit test.

 

Credit in SIS and signed credit in Credit Book is needed.

 

 

Syllabus

Last update: PharmDr. Bc. Eva Dědečková (27.02.2021)

LECTURES:

1.   Pharmacodynamics – specific and non-specific mechanism of drug action.

2.   Pharmacodynamics - quantitative aspects of drug-receptor interaction.

3. Pharmacokinetics - drug permeation through biomembranes, basic pharmacokinetic processes, and parameters. Absorption.

4. Pharmacokinetics - distribution and metabolism of drugs.

5. Pharmacokinetics - drug excretion. Elimination according to 1st and 0th order kinetics, pharmacokinetic parameters of elimination, and their significance.

6. Pharmacokinetic basis of drug dosing, single and repeated drug administration.

7. Individualization of pharmacotherapy: pharmacogenetics, gene therapy. Biological treatment.

8. Chemical mediators and vegetative nervous system - sympathetic.

9. Vegetative nervous system - parasympathetic.

10. Antiepileptics.

11. Psychopharmaceuticals - antidepressants, thymoprophylactics, antipsychotics.

12. Psychopharmaceuticals - anxiolytics, hypnotics.

13. Central and peripheral muscle relaxants. General and local anaesthetics.

14. Infusion therapy, enteral and parenteral nutrition. Vitamins, minerals.