SubjectsSubjects(version: 945)
Course, academic year 2023/2024
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Infection and Geographic Medicine - CVSE5P0045
Title: Infekční a tropické lékařství
Guaranteed by: Department of Infectious Diseases 3FM CU and UHB (12-INF)
Faculty: Third Faculty of Medicine
Actual: from 2023
Semester: both
Points: 2
E-Credits: 2
Examination process:
Hours per week, examination: 0/50, C+Ex [HS]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
Key competences:  
State of the course: taught
Language: Czech, English
Teaching methods: full-time
Teaching methods: full-time
Level:  
Note: you can enroll for the course in winter and in summer semester
Guarantor: MUDr. Hynek Bartoš, Ph.D.
doc. MUDr. Olga Džupová, Ph.D.
Classification: Medicine > Clinical Disciplines
Examination dates   Schedule   
Annotation -
Last update: doc. MUDr. Olga Džupová, Ph.D. (15.02.2024)
The subject Infection and tropical medicine is addressed to students of general medicine, 5th year. Students learn pathogenesis, clinical presentation, diagnostics, differential diagnosis and principles of therapy of infectious diseases. The spectrum of diseases follows the actual needs of the subject in Europe with more focus on the Czech Republic.
Aim of the course -
Last update: doc. MUDr. Olga Džupová, Ph.D. (15.02.2024)

The primary goal is to teach students to diferentiate infectious diseases, to diagnose them and adopt the principles of treatment.
The secondary goal is to understand relations between microorganisms and human beings, to be aware of the global aspect of infectious diseases, to understand the specific position of antibiotic (antiinfection) therapy among other therapeutic modalities.

Literature -
Last update: doc. MUDr. Olga Džupová, Ph.D. (15.02.2024)

PPT presentations from the seminars available in Výuka

Hobstova J (ed.): Infectious Diseases. 2nd ed. Charles University in Prague, Karolinum Press 2012

Banister BA, Begg NT, Gillespie SH. Infectious Disease. 2nd ed. Blackwell Science Ltd. Oxford 2000

Wilks D, Farrington M, Rubinstein D. The Infectious Diseases Manual. 2nd ed. Blackwell Science Ltd. Oxford 2003

whichever textbook of Infectious diseases

 

For microbiology knowledge augmentation, any of the following:

Murray P, Rosenthal KS, Pfaller MA. Medical Microbiology, 8th ed., Elsevier Mosby 2015

Goering R, Dockrell H, Zuckerman M, Chiodini P. Mims' Medical Microbiology and Immunology.

https://www.elsevier.com/books/mims-medical-microbiology-and-immunology/goering/978-0-7020-7154-6

Barer MR, Irving WL. Medical Microbiology. A Guide to Microbial Infections: Pathogenesis, Immunity, Laboratory Investigation and Control . 19th Ed.

https://www.us.elsevierhealth.com/medical-microbiology-9780702072000.html

Teaching methods -
Last update: doc. MUDr. Olga Džupová, Ph.D. (15.02.2024)

Teaching methods: seminars, simulated practices with presentation of case reports, bedside training.

Requirements to the exam -
Last update: doc. MUDr. Olga Džupová, Ph.D. (15.02.2024)

The teaching is onsite, not online. We recommend students to prepare for each topic by individual study from the literature recommended in SIS and presentations available in Výuka. Please, follow carefully the time-table in Výuka and/or in the e-Calendar.

The start of lessons each day was assessed at 8,15 AM. Students are expected to come to the 6th floor of the Department of Infectious Diseases, building no. 7 in the University Hospital Bulovka. The entrance for staff and students is from the bridge on the 2nd floor. Students should bring their stethoscopes, FFP2 respirators and hospital shoes, at the department they will receive gowns.

The only but strict requirement for being granted with the credit is 80% attendance at classes. The complete course consists of 20 two-hour units: 10 seminars, 7 virtual clinical training lessons and 3 bedside training lessons. Absence in 2 days is permitted, regardless of seminar or clinical training. We recommend a full attendance, as at the exam we require information provided at classes. 

Compensation for missed classes will be allowed by attendance of the missed classes with other study group in the further course of the academic year. It is not possible to compensate the missed classes in the form of extra classes or practices at the infectious diseases department.

The credit will be given to the student upon completion of the mandatory attendance and will be written into SIS immediately after the course. It will not be possible to register for the exam without credit.

The oral exam will take place onsite at the department in the winter or summer exam period. During both semesters, a limited amount of preterm exam dates will be assessed.

 

 

 

Questions for exam in Infection and geographic medicine, General medicine, 5th year

  

Part I:  Organ-oriented approach and special situations

 

1.      Acute tonsillopharyngitis (sore throat) syndrome

 

2.      Acute epiglottitis, laryngitis and laryngotracheitis

 

3.      Community-acquired pneumonia

 

4.      Purulent meningitis (incl. neonatal age)

 

5.      Aseptic meningitis and encephalitis

 

6.      Acute diarrhoea

 

7.      Skin and musculoskeletal infections of bacterial origin

 

8.      Infectious diseases with maculopapular exanthem

 

9.      Infectious diseases with vesicular and pustular exanthem

 

10.  General overview of liver infections. Parenchymatic infections diffuse and focal, hepatobiliary infections

 

11.  Upper and lower urinary tract infections

 

12.  Infective endocardititis

 

13.  Lymphadenopathy and lymfatic tissue infections

 

14.  Sepsis, septic shock

 

15.  Fever of unknown origin. Diagnostic approach, common causes in temperate climatic zones.

 

16.  Fever in patient returning from tropics

 

17.  Diarrhoea in patient returning from tropics

 

18.  Infectious diseases during pregnancy. Congenital and perinatal infections.

 

19.  Biological weapons, with emphasis on anthrax.

 

20.  Animal bite infections (lyssa, cat-scratch disease).

 

21.  Hospital-acquired infections.

 

 

Part II :          Pathogen-oriented approach

 

1.      Influenza, covid-19 and other viral respiratory tract infections

 

2.      Arboviral infections (tick-borne encephalitis, dengue fever, yellow fever)

 

3.      Epidemic parotitis and enteroviral infections (Coxsackie, ECHO viruses, polioviruses)

 

4.      HSV and VZV infections

 

5.      EBV and CMV infections

 

6.      HIV infection. Routes of infection, classification, clinics, diagnosis, therapy, prognosis.

 

7.      Opportunistic infections in HIV disease. Clinics, diagnosis, therapy, prophylaxis

 

8.      Viral hepatitis A-E

 

9.      Staphylococcal infections. Toxic shock syndrome

 

10.  Streptococcal infections. Toxic shock syndrome

 

11.  Pneumococcal infections

 

12.  Meningococcal invasive disease (incl. pathogenesis)

 

13.  Salmonellosis and campylobacteriosis

 

14.  Shigella and E.coli diarhoea infections

 

15.  Spirochetal infections (esp. Lyme borreliosis, leptospirosis)

 

16.  Chlamydia and Mycoplasma infections

 

17.  Clostridial toxin-mediated diseases (esp. botulism, tetanus)

 

18.  Fungal infections in immunocompetent and immunocompromised patients

 

19.  Amoebiasis, giardiasis

 

20.  Malaria

 

21.  Intestinal helminthiases (intestinal nematodes, cestodes)

 

 

 

Part III: Antiinfective therapy

 

1.       Beta-lactam antibiotics. Subgroups, antibacterial spectra, indications, adverse effects, mechanisms of resistance.

 

2.       Penicillins. Drugs, antibacterial spectra, indications, doses, adverse effects.

 

3.       Cephalosporins. Drugs, antibacterial spectra, indications, adverse effects.

 

4.       Macrolides, lincosamides. Drugs, antibacterial spectra, indications, adverse effects.

 

5.       Tetracyclines, chloramphenicol, metronidazol. Drugs, antibacterial spectra, indications, adverse effects.

 

6.       Aminoglycosides and glycopeptides. Drugs, antibacterial spectra, indications, adverse effects. Monitoring of therapy.

 

7.       Fluoroquinolones and cotrimoxazol. Drugs, antibacterial spectra, indications, adverse effects.

 

8.       Antibiotic therapy of Gram-positive infections

 

9.       Antibiotic therapy of Gram-negative infections

 

10.   Antibiotic therapy of anaerobic infections

 

11.   Antibiotic therapy of nosocomial infections (resistant bacteria)

 

12.   Chemotherapy of fungal infections. Drugs, indications

 

13.   Chemotherapy of viral infections. Indications, drugs

 

14.   Hyperimmune specific immunoglobulins as part of complex therapy of infections

 

15.   Physiological human microbial flora and its changes due to antibiotics (incl. antibiotic - associated colitis).

 

Syllabus -
Last update: doc. MUDr. Olga Džupová, Ph.D. (15.02.2024)

Seminars:

Patophysiology, diagnostics and treatment of sepsis

CNS infections

HIV infection

Congenital and perinatal infections 

Strategy and tactics of antibiotic therapy

Influenza, covid-19 and other acute respiratory tract infections

Hospital-acquired infections 

Imported infections

Infections in specific host 

Parasitic infections

Simulated practice:

Exanthema infections

Acute diarrhea, principles of rehydration and isolation

Life-threatening infections 

Clinical cases – HIV and opportunistic infections 

Clinical cases – CNS infections, infections of the spine 

Clinical cases – zoonotic infections, borreliosis 

Clinical cases – Pneumonia and another respiratory tract infections

 
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