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Last update: prof. MUDr. Michal Anděl, CSc. (30.09.2016)
The prerequisit for attendace at the course DEGHAS is the succesfull examination from general pathology, general pharmacology and Microbiology and infectious diseases. The course diabetology-endocrinology-gastroenterology-hepatology and abdominal surgery (DEGHAS) has 5 weeks. In the first two weeks the students will learn the basic principles of the endocrine and metabolic diseases with special emphasis to diabetes mellitus. In the 3rd week, the most common diseases of the oral cavity, esophagus, stomach, duodenum, intestines, biliary ducts and pancreas will be discussed. The entire 4th week is dedicated to the liver diseases. Gastrointestinal surgery including topographic anatomy of the abdominal cavity will be presented in the 5th week. Acute abdominal emergencies will be discussed in separate seminars. |
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Last update: prof. MUDr. Pavel Kraml, Ph.D. (21.09.2020)
In this course, the diseases will be presented from pathology and pathophysiology to clinical manifestation and basic diagnostic and therapeutic procedures or prevention. There will be 2 seminars and 1 clinical presentation in the morning hours. Lectures will be held according to schedule, always at 14:00. The course is obligatory for all students! Additionally, presence at the clinical presentations and seminars will be always confirmed by the assigned teacher. Credit: 80 % of presence in clinical presentations and seminars is required.
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Last update: prof. MUDr. Pavel Kraml, Ph.D. (05.09.2017)
Prerequisit for examination is succesfull examination from the General pathology, General pharmacology and Microbiology and infection Condition for obtaining the credit is 80% of presence at clinical presentations and seminars. Oral examination can be taken only on assessed terms. Student will be given 3 questions: 1) pathology, 2) pharmacology, 3) clinical topic. . |
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Last update: prof. MUDr. Pavel Kraml, Ph.D. (10.12.2019)
DIABETOLOGIE-ENDOKRINOLOGIE 1. Patologie endokrinních orgánů (semináře, praktická cvičení, přednáška) 2. Principy endokrinních regulací a jejích poruchy - patofyziologie 3. Energetická metabolismus-patofyziologie 4. Principy supresivní a substituční léčby v endokrinologii - farmakologie 5. Diabetes mellitus 1. typu 6. Diabetes mellitus 2. typu 7. Komplikace diabetu 8. Farmakologická léčba diabetu 9. Ateroskleróza 10. Hyperlipoproteinémie 11. Poruchy vodního a minerálového hospodářství 12. Poruchy funkce štítné žlázy, nadledvin, gonád, hypofýzy (semináře, přednášky, kasuistiky) 13. Poruchy kalciofosfátového metabolizmu, osteoporóza, osteomalacie 14. Poruchy výživy
GASTROENTEROLOGIE 1. Onemocnění dutiny ústní a jícnu (seminář, stáž, přednáška) 2. Nádory žaludku (seminář, stáž, přednáška) 3. Nenádorová onemocnění žaludku, vředová choroba gastroduodenální (stáž, předn., seminář) 4. Crohnova choroba. Ulcerózní kolitida (stáž, přednáška, seminář) 5. Akutní a chronická pankreatitida (stáže, přednášky, semináře) 6. Karcinom pankreatu (stáže, přednášky, semináře) 7. Onemocnění žlučníku a žlučových cest (stáž, přednáška, seminář) 8. Nádory tlustého střeva (stáž, přednášky, seminář) 9. Antiulcerózní terapie - farmakologie (seminář) 10. Mechanismy regulace motility a sekrece GIT - farmakologie (přednáška) 11. Patologie GIT (praktická cvičení) 12. Farmakoterapie vředové choroby, GERD, NSA gastropatie 13. Farmakoterapie IBD
HEPATOLOGIE 1. Teoretické základy hepatologie v klinických souvislostech (seminář) 2. Zobrazovací metody v hepatologii (seminář) 3. Typy jaterních onemocnění, jejich diagnostika (seminář) 4. Autoimunitní a cévní choroby jater (seminář) 5. Metabolické choroby jater (seminář) 6. Nealkoholová steatohepatitída a alkoholové poškození jater (seminář) 7. Cirhóza jater. Nádory jater (seminář) 8. Jaterní selhání (seminář) 9. Chronická hepatitída B a C (seminář) 10. Transplantace jater (seminář) 11. Kazuistiky v hepatologii (problémově orientovaný seminář) 12. Vyšetření hepatologicky nemocného (praktika)
BŘIŠNÍ CHIRURGIE 1. Klinická anatomie-topografie a cévní zásobení břicha (seminář) 2. Patofyziologie chorob žlučníku, žlučových cest a pankreatu (seminář) 3. Chirurgie jícnu, žaludku a duodena (stáž) 4. Chirurgie žlučníku a žlučových cest (stáž) 5. Benigní a maligní onemocnění tlustého střeva a konečníku (stáž) 6. Záněty a nádory pankreatu (přednáška) 7. Zánětlivé náhlé příhody břišní (seminář/stáž) 8. Ileózní náhlé příhody břišní (seminář/stáž) |
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Last update: MUDr. Jan Matouš (13.10.2014)
Questions for oral examination in DEGHAS Academic year 2014/2015
Legend: PAT-pathology PHAR-pharmacology
1. Tumors of the thyroid glynd- PAT Insulin secretagogues: sulphonylureas and glinides -PHAR Hypercholesterolemia - clinic: symptoms, findings 2. Parathyroid tumors -PAT Oral antidiabetic drugs affecting insulin sensitivity - PHAR Hypertriglyceridemia - clinic: symptoms, findings 3. Clinical anatomy of the thyroid gland Insulins: indications, side effects - PHAR Type 1 diabetes mellitus - clinic: symptoms, findings 4. Pathology of the adrenals - PAT Types of insulin - PHAR Type 1 diabetes mellitus - clinic: symptoms, findings 5. Tumors of the esophagus and stomach - PAT Insulin: mechanism of action - PHAR Type 2 diabetes mellitus - clinic: symptoms, findings 6. Tumors of the small intestine and colon - PAT Antidiabetics according to their mechanism of action - PHAR Plasma lipid goals according to the level of cardiovascular risk 7. Precanceroses of the GIT - PAT Insulin secretagogues: incretins and gliptins (DPP-4 inhibitors) - PHAR Chronic specific diabetes complications - clinic: symptoms, findings 8. Primary and secondary tumors of the liver - PAT Drugs used in therapy of peptic ulcer - PHAR Hereditary forms of diabetes - clinic: symptoms, findings 9. Liver cirrhosis - PAT Metabolic action, safety and impact on prognosis of different antidiabetics Idiopatic bowel diseases - clinic: symptoms, findings 10. Tumors of the gallbladder, biliary ducts and papilla Vateri - PAT Antidiabetics: intestinal glycosidase inhibitors and gliflozins - PHAR Wilson’s disease - clinic: symptoms, findings 11. Pancreatic tumors - PAT Artificial sweeteners. Anti-obesity drugs. - PHAR Diabetic hyperglycemic ketoacidotic coma - clinic: symptoms, findings 12. Neuroendocrine tumors - PAT Antiemetic drugs - PHAR Acromegaly, gigantism - clinic: symptoms, findings 13. Chronic hepatitis - PAT Drugs affecting the intestinal motility - PHAR Hyperthyroidism - clinic: symptoms, findings 14. Alcohol organ damage - PAT Solutions used for parenteral and enteral nutrition. I.v administration of potassium Diabetic hyperosmolar non-ketogenic coma - clinic: symptoms, findings 15. Biochemistry and pathogenesis of lactic acidosis - PATOPHYS Drugs used in diarrhea and constipation - PHAR Hypoglycemia and hypoglycemic coma - clinic: symptoms, findings 16. Basic energetic substrates for brain, hepatocytes, myocytes, tubular cells, enterocytes, endothelial cells, enterocytes - PHYSIOLOGY Proton pump inhibitors: principles of treatment, indications and side effects - PHAR Insulin administration and insulin pumps. Technology and clinic. 17. Pituitary tumors - PAT Drugs causing damage to esophageal, gastric and duodenal mucosa - PHAR Hyperuricemia and gout - clinic: symptoms, findings 18. Diarrhea - PATHOPHYS Helicobacter pylori eradication strategy - PHAR Epidemiology of diabetes mellitus 19. Metabolic acidosis - PATHOPHYS Treatment of hyperuricemia and its complications - PHAR Chronic non-specific complications of diabetes - clinic: symptoms, findings 20. Metabolic alkalosis - PATHOPHYS Treatment of idiopathic bowel diseases - PHAR Pituitary tumors - clinic: symptoms, findings 21. Respiratory acidosis - PATHOPHYS Treatment of osteoporosis - osteoanabolic approach - PHAR Complications of peptic ulcer - clinic: symptoms, findings 22. Respiratory alkalosis - PATHOPHYS Biochemical and athropometric methods in nutritional status assessment Gestational diabetes - definition, - clinic: symptoms, findings 23. Cholestatic syndromes - PAT Dietary principles in atherosclerosis prevention Addison’s disease - clinic: symptoms, findings 24. Ascites - PAT Pharmacohterapy of pituitary disorders and use of pituitary hormones - PHAR Cusching’s syndrome and Cusching’s disease - clinic: symptoms, findings 25. Syndrom of portal hyprtension - PAT Diabetic diet Insulinoma - clinic: symptoms, findings 26. Hemochromatosis - PAT Vegetarian diet - types and risks Obesity - clinic: symptoms, findings 27. Anabolic and catabolic states - PATHOPHYS Indications for vitamin and trace element supplementation - PHAR Inflammatory acute abdominal - clinic: symptoms, findings 28. Pituitary-adrenal axis - PATHOPHYS Dietary measures in acute and chronic pancreatitis Principles of bariatric surgery and endoscopic procedures 29. Mechanisms of hormone action-PATHOPHYS Laxatives - PHAR Polycystic ovary syndrome - clinic: symptoms, findings 30. Intestinal hormones - PATHOPHYS Basic principles of intensified insulin therapy in Type 1 diabetes mellitus MEN and APS syndromes - clinic: symptoms, findings 31. Pathogenesis of atherosclerosis - PAT Treatment of osteoporosis - antiresorption approach-PHAR Acute abdomen - ileus - clinic: symptoms, findings 32. Pathology of atherosclerosis - PAT Spasmolytics - PHARM Preparing for endoscopy procedures in gastroenterology 33. Islets of Langerhans - normal histology Treatment of thyreotoxicosis. Thyreostatics - PHAR Basic examination in acute abdomen - clinic: symptoms, findings 34. Histology of the liver lobules and types of liver necrosis - PAT Treatment of hypothyroidism - supplementation therapy- PHAR Acute gastrointestinal bleeding - clinic: symptoms, findings 35. Histology of the pituitary gland. Pituitary tumors - PAT Treatment of hyperaldosteronism - PHARM NAFLD - clinic: symptoms, findings 36. Non-tumor diseases of the thyroid gland - PAT Diet in gallbladder and biliary duct diseases Tuberculosis of the GIT - clinic: symptoms, findings 37. Pathophysiology of hypoglycemia Lactose intolerance Goals in diabetes therapy: HbA1c, blood glucose, arterial blood pressure 38. Pathogenesis of Type 1 diabetes mellitus PATHOPHYS Gastroesophageal reflux disease - PHAR Complications of ulcerative colitis - clinic: symptoms, findings 39. Pathogenesis of Type 2 diabetes mellitus PATHOPHYS Hepatotoxic drugs - PHAR Celiac disease - clinic: symptoms, findings 40. Pathogenesis of cholecystolithiasis - PAT Diabetic diet Treatment of hypoglycemia |