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IA - Biochemistry I. - CSFBXX41C

Title:	IA - Biochemie I.
Guaranteed by:	Department of Biochemistry, Cell and Molecular Biology 3FM CU (12-BIOC)
Faculty:	Third Faculty of Medicine
Actual:	from 2016
Semester:	summer
Points:	4
E-Credits:	4
Examination process:	summer s.:
Hours per week, examination:	summer s.:22/30, other [HS]
Extent per academic year:	0 [hours]
Capacity:	unknown / unknown (unknown)
Min. number of students:	unlimited
4EU+:	no
Virtual mobility / capacity:	no
Key competences:
State of the course:	not taught
Language:	Czech
Teaching methods:	full-time
Teaching methods:	full-time
Level:
Additional information:	http://www.lf3.cuni.cz/en/departments/chemie/vyuka/

Guarantor:	prof. RNDr. Eva Samcová, CSc. Mgr. Vladimíra Kvasnicová
Classification:	Medicine > Basic Sciences
Attributes:	Modul IA

Examination dates Schedule

Annotation -

Last update: Miroslava Vojtová (13.08.2008)

Structure and function of human body (Module IA) involves basic theoretical subjects: anatomy, histology, physiology and biochemistry. In summer semester of the first year module IA is composed of 3 courses: Respiration, blood and body fluids, Urogenital system. Acid-base balance, Digestion and resorption. The arrangement of the systems is coordinated with the teaching of the same objects in three other disciplines (anatomy, histology, physiology).

Aim of the course -

Last update: Miroslava Vojtová (13.08.2008)

Lessons of biochemistry in summer semester are focused on biochemical processes occuring in the human body (blood, respiration, urogenital and digestive system). In practical trainings students work with their own biological material (blood, urine).

Literature -

Last update: Mgr. Vladimíra Kvasnicová (03.10.2010)

Murray, Robert K.: Harper´s biochemistry, 24th ed. (or the other),1996, ISBN 0838563115
Pamela C. Champe, Richard A. Harvey: Lippincott´s Illustrated Reviews - Biochemistry, ISBN 0-397-51091-8
Jan Koolman, Klaus-Heinrich Röhm: Color Atlas of Biochemistry, Thieme, Stuttgard, 1996, ISBN 3-13-100371-5
J.G.Salway: Metabolism at a Glance, 2nd ed., Blackwell Science Ltd, 1999, ISBN 0-632-05274-0
Thomas M. Devlin et al.: Textbook of Biochemistry With Clinical Correlations, 4th ed., ISBN 0-471-15451-2

Teaching methods -

Last update: Miroslava Vojtová (13.08.2008)

Lectures, seminars, 4 practical trainings

Requirements to the exam -

Last update: Miroslava Vojtová (13.08.2008)

Credit requirements:

1) Successful completion of all practical trainings (A1 - A4)

Missing practical trainings can be compensated during examination period in June (the date of the alternative practical training will be advised in May). A report from each task must be submited to your teacher one week after the practical training at the latest.

2) Three oral testings

Each student will be tested three times during the summer semester by a group teacher; topics of the testings are the same as ones of the Integrated Conferences: 1. Respiration, Blood and Body Fluids; 2. Urogenital system, Acid-Base Balance; 3. Digestion and Resorption, Intermediary Metabolism; dates and form of the testing will be arranged by the group teacher. Required knowledge to each testing is available at web pages of department.

Syllabus -

Last update: Miroslava Vojtová (13.08.2008)

Lectures:

Transport of oxygen and carbon dioxide

Biochemistry of blood cells

CONFERENCE - respiration, blood, body fluids

Acid-base balance

Functional biochemistry of digestive tract

Energy metabolism

CONFERENCE - urogenital system, acid-base balance

Biochemistry of liver cell

General toxicology

Biotransformation of xenobiotics

Vitamins in metabolism

Free radicals and antioxidants

CONFERENCE - digestion and resorption

Seminars:

Introduction to practical trainings (theory: blood collection, electrophoresis, centrifugation, a guide to the labs)

Blood serum proteins electrophoresis - practical training

Hemoglobin - structure, function and metabolism

Chemical examination of urine. Urine sediment - practical training

Acid - base balance

Determination of blood glucose level. Interpretation of oGTT - practical training

Alkali phosphatase (ALP) - determination of serum activity - practical training

Biochemistry of liver cell

Biotransformation of xenobiotics

Intermediary metabolism relationships

Entry requirements -

Last update: Miroslava Vojtová (13.08.2008)

Successful passing of the entrance examination (biology, chemistry, physics).