SubjectsSubjects(version: 945)
Course, academic year 2014/2015
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Fundamentals of Toxicology - B02201 (Adiktologie)
Title: Základy toxikologie
Guaranteed by: Institute of Forensic Medicine and Toxicology First Faculty of Medicine Charles University and General University Hospital in Prague (11-00360)
Faculty: First Faculty of Medicine
Actual: from 2014 to 2014
Semester: winter
Points: 1
E-Credits: 1
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, MC [HT]
Extent per academic year: 30 [hours]
Capacity: unlimited
Min. number of students: unlimited
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Explanation: Doc. M. Balíková
Additional information: http:// Ústav soudního lékařství a toxikologie
Old code: 56
Guarantor: doc. Ing. Marie Balíková, CSc.
Attributes: Adiktologie
Teoretický předmět
Pre-requisite : {pro kontrolu splnění PP v 1. úseku BADI prezenční dá se použít pro nahrání povinného bloku prvákům PVP musí být pro kontroly zvlášť}, B01439, B01442
Annotation -
Last update: doc. Ing. Marie Balíková, CSc. (01.10.2012)
Analytical toxicology in present. Metabolism of toxic substances, pharmacokinetics, pharmacodynamics, toxic effects. Differencial diagnostics of intoxications. Drug abuse. Systematic toxicological analysis.Screening and confirmation. Alternative matrices in toxicology. Drugs and driving under influence. Interpretation of findings. Interesting case reports.
Syllabus -
Last update: doc. Ing. Marie Balíková, CSc. (01.10.2012)

Introduction to forensic and clinical toxicology. Disposition of xenobiotics in organism. Biotransformation. Industrials, pharmaceuticals, illicit drugs. Systematic toxicological analysis for unknown drug. Screening and confirmation. Alternative biological matrices and their significance in toxicology. Drugs of abuse, legislation. Drugs and driving under influence. Interpretation of toxicological findings. Interesting case reports. Morbidity and mortality in context of drug abuse.

Literature - Czech
Last update: doc. Ing. Marie Balíková, CSc. (02.10.2023)

1) H. Lüllmann, K. Mohr, M. Wehling: Farmakologie a toxikologie. Grada Publ., Praha 2002;
2) J. Večerková: Biotransformace léčiv a její význam pro toxikologickou praxi. Karolinum, Praha 1997;
3) M. Balíková: Forenzní a klinická toxikologie. Laboratorní toxikologická vyšetření. Galén, Praha 2007; 2017
4) J. Patočka: Vojenská toxikologie. Grada publ. 2004;
5) V. Hrdina aj.: Přírodní toxiny a jedy. Galén 2004
6) O. H. Drummer, M. Odell: The Forensic Pharmacology of Drugs of Abuse. Arnold publ. London, 2001.
7) R. C. Baselt: Disposition of Toxic Drugs and Chemicals in Man. 6th ed., Biomedical Publications, Foster City, California, 2002;
8) R. J. Flanagan et al.: Fundamentals of Analytical Toxicology. Wiley-VCH, West Sussex, 2007.

 
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