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Last update: doc. Ing. Marie Balíková, CSc. (07.06.2017)
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Last update: doc. Ing. Marie Balíková, CSc. (07.06.2017)
Introduction to forensic and clinical toxicology. Disposition of xenobiotics in organism. Biotransformation. Industrials, pharmaceuticals, illicit drugs. Systematic toxicological analysis for unknown drug. Screening and confirmation. Preliminary immunochemical detection. Principles of controlled extraction of organic substances from biological samples. Gas and liquid chromatography in toxicology. Principles of mass spectrometry and its significance for identification of unknown poison in a trace toxicological analysis. Development and validation of toxicological methods. Alternative biological matrices and their significance in toxicology. Drugs of abuse, legislation. Drugs and driving. Interpretation of toxicological findings. Interesting case reports. |
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Last update: doc. Ing. Marie Balíková, CSc. (07.06.2017)
Doporučená literatura:
1) K. Mohr, M. Wehling, H. Lüllmann: Farmakologie a toxikologie. Grada Publ.2002, Praha 2) M. Balíková: Forenzní a klinická toxikologie. Laboratorní toxikologická vyšetření. Galén 2007, Praha 3) 1) J. Večerková: Biotransformace léčiv a její význam pro toxikologickou praxi. Karolinum 1997, Praha 4) J. Patočka aj. Vojenská toxikologie. Grada publ. 2004, Praha. 5) R. C. Baselt: Disposition of Toxic Drugs and Chemicals in Man. 9th ed., Biomedical Publications 2011, Seal Beach, California 6) R. J. Flanagan et al.: Fundamentals of Analytical Toxicology, Wiley 2007, West Sussex 7) O. H. Drummer, M. Odell: The Forensic Pharmacology of Drugs Abuse. Arnold publ. 2001, London. 8) F. T. Peters, H. H. Maurer: Bioanalytical method validation and its implications for forensic and clinical toxicology - A review. Accred. Qual. Assur. 7 (2002) 441-449. |
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Last update: doc. Ing. Marie Balíková, CSc. (30.09.2019)
Přednáška vždy ve čtvrtek od 15:00 hod. v posluchárně KDDL, 2. patro, pavilon E, Ke Karlovu 2, Praha 2 |