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In the subject Haematology and Oncology students will be introduced to the epidemiology, pathogenesis, diagnostics, staging and therapy of both solid tumours and hematological malignancies as well as non-malignant hematological disorders. Theoretical introduction in form of lectures, that provides an overview of crucial topics in the subject, are followed by seminars that provide more detailed insight into respective diseases, their taxonomy, special pathology, diagnostics, clinical course and treatment. During the seminars on non-malignant hematology students learn basics of hematology laboratory practice, both morphology and coagulation part, with laboratory results inerpretation and basics of rational haemotherapy (transfusiology). At the practical lectures students are examining patients with specific malignant diseases. Haematooncological part of practical lectures are focused on case studies with differential diagnosis and treatment. The access to patients with haematological malignancies is limited because of deep immunosupression in most of them, but whenever it is possible, patients with clear signs of haematological disease, especially with lymphadenopathy and splenomegaly, are demonstrated to the students. In the oncological and haematooncological part of the course students learn basics of oncology therapy according to the evidence based medicine, including tageted therapy and modern supportive and palliative care.
Preventive care and early diagnosis principles of both malignant and non- malignant haematologic diseases will be also mentioned.
Last update: Kozák Tomáš, prof. MUDr., Ph.D. (30.09.2022)
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Haematology/haematooncology: students will be able to establish basic differntial diagnosis of both malignant and non-malignant haematologic diseases based on typical clinical course and laboratory and imaging studies. They will be able to propose further examination algorithm after obtaining various abnormal readings in morphology and coagulation. Oncology: students will be introduced to epidemiology, clinical signs, staging and basics of treatment of solid tumors. After that they will be able to determine diagnostic and staging algorithm for most frequent neoplastic diseases and propose affective management. The course will also enable to gain practical skills in communication with an oncology patient. Last update: Kozák Tomáš, prof. MUDr., Ph.D. (30.09.2022)
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Haematology part: Hoffbrand V.A., Moss P.A.H: Hoffbrand´s Essential Haematology, 7. edition, Wiley Blackwell, 2015
Last update: Kozák Tomáš, prof. MUDr., Ph.D. (30.09.2022)
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Lectures, seminars, practice at the respective department We face an unpredictable epidemiology situation in the fall 2020. It is possible that both lectures and seminars in summer semester 2021 will be still organized in a distant mode. The practical teaching should be held in a standard manner or with some modifications that will be announced. Last update: Kozák Tomáš, prof. MUDr., Ph.D. (25.09.2020)
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Credit test: if there are no epidemiology restrictions posed on our teaching activity in the spring/summer 2023, a written test for credit will be held at the time of last practical lecture. The credit test will consist of 20 questions (10: oncology, 10: haematology). Each question will have 4 answers, just one answer will be correct. At least 16 correctly answered questions out of 20 will be required for succesful completion of the test. In case of any significant restrictions and/or the student cannot attend the lecture and write the test because of epidemiology situation, credits will be given to students at the oral exam. The oral exam: 3 questions to be answered (1 haematology or haematooncology, 1 oncology, 1 disease-specific pharmacology/priciples of (hemato)oncology suportive care/transfusiology). To be eligible for sign up for the oral exam the student must have passed the exam from General Foundations of Pathology and Pathophysiology (CVSE3P0011) and the credit test mentioned above. Terms for final exams will be posted in time in SIS (EXAM DATES).
Topics/questions HEMONK for oral exam 3. year, general medicine
Topics & Questions – Oncology School year 2022/2023
Questions – Hematology for school year 2022/2023 1. Laboratory examination in haematology 2. Morfological classification of anaemia 3. Iron defficiency anaemia 4. Pernicious anaemia 5. AIHA 6. TTP/HUS 7. Thalassemia and sicle cell disease 8. PNH 9. Hereditary spherocytosis and G-6-P-D deficiency 10. Aplastic anaemia 11. Neutrophilia and its causes 12. Neutropenia and its causes 13. Eosinophilia and its causes 14. Lymphocytosis and its causes 15. Thrombocytopenia: causes and 16. ITP 17. Thrombocytosis and its causes 18. Thrombocytopathy 19. Acute myeloid leukaemia (AML) 20. Acute lymphoblastic leukaemia (ALL) 21. Chronic myelogenous leukaemia (CML) 22. Primary (idiopathic) myelofibrosis (PMF) 23. Polycythaemia vera 24. Essential thrombocytaemia (ET) 25. Chronic lymphocytic leukaemia (CLL) 26. Lymphoma classification and staging 27. Hodgkin's lymphoma (HL) 28. Diffuse large B cell lymphoma (DLBCL) 29. Mantle cell lymphoma (MCL) 30. Follicular lymphoma (FL) 31. Burkitt's lymphoma (BL) 32. Marginal zone lymphoma (MZL) 33. Waldenström's macroglobulinaemia 34. T- cell lymphoma 35. MGUS 36. Multiple myeloma 37. Alkylating agents, antimetabolites and topoisomerase inhibitors in the treatment of neoplastic diseases F 38. Anthracyclins, platinating agents, nukleoside analogs in the treatment of neoplastic diseases F 39. Corticosteroids in the treatment of neoplastic diseases F 40. Targetted („biological“) therapy in hematooncology F 41. Supportive care in hematooncology, treatment of pain F 42. Hemophilia 43. Von Willebrand's disease 44. Anticoagulation treatment. Heparin, Warfarin and new oral anticoagulants F 45. Antiaggregation treatment F 46. DIC 47. Thrombosis a thrombophilia 48. Antiphospholipid syndrome, lupus anticoagulans 49. Blood products, indication for transfusion and complications 50. Blood derivatives, indication to administration, complications
Last update: Kozák Tomáš, prof. MUDr., Ph.D. (30.09.2022)
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Syllabus HEMONK 2022/2023
Last update: Kozák Tomáš, prof. MUDr., Ph.D. (30.09.2022)
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