SubjectsSubjects(version: 945)
Course, academic year 2023/2024
   Login via CAS
--:--
 
 Search ... Teachers Departments Classes Classification View by plans Setup
 
 
 
 Details
 
 
 
 
The Basics of Cancer Molecular Biology - B83588 (elective subject)
Title: The Basics of Cancer Molecular Biology
Guaranteed by: Department of Oncology First Faculty of Medicine Charles University and Thomayer University Hospital (11-00451)
Faculty: First Faculty of Medicine
Actual: from 2023
Semester: summer
Points: 3
E-Credits: 3
Examination process: summer s.:
Hours per week, examination: summer s.:12/0, C [HS]
Extent per academic year: 12 [hours]
Capacity: 15
Min. number of students: 3
4EU+: no
Virtual mobility / capacity: no
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Note: course for students of another faculty
course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: MUDr. Ludmila Boublíková, Ph.D.
Attributes: Lékařství
Klinický předmět
Annotation
Last update: Marcela Holanová (12.07.2023)
It is an interdisciplinary cross-curricular subject that summarizes the essential aspects of the molecular biology of malignant tumors and puts them in the context of their clinical behavior, course of the disease and response to treatment. Each topic covers basic biological facts and principles, their specific application in the development of oncological diseases, method of detection, possibilities of use in the diagnosis and treatment of tumors.
Syllabus
Last update: Marcela Holanová (12.07.2023)
1. Principal aspects of malignancies, tumor pathogenesis, cancer stem cells
2. Genetic predispositions, hereditary cancer syndromes
3. Cell signaling, growth factor receptor pathways
4. DNA damage and repair, epigenetic alterations
5. Cell cycle, ploidy, chromosomal aberrations
6. Apoptosis, cell immortalization
7. Cancer cell metabolism
8. Tumor radiobiology
9. Angiogenesis, metastatic process, circulating tumors cells, cell-free DNA and miRNAs
10. Immune response, tumor microenvironment, microbiome
11. Methods in molecular biology, predictive testing, tumor molecular classification
12. Molecular-based therapy, gene therapy

Education plan -
Schedule by date
Day Date Description Teacher Files Note Hodnocení
Wednesday06.03.202414:00 - 15:30 1. Principal aspects of malignancies, tumor pathogenesis, cancer stem cells 2. Genetic predispositions, hereditary cancer syndromes Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090 
průměr: 5, hodnoceno: 1x
Wednesday13.03.202414:00 - 15:30 3. Cell signaling, growth factor receptor pathways 4. DNA damage and repair, epigenetic alterations Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090 
průměr: 5, hodnoceno: 1x
Wednesday20.03.202414:00 - 15:30 5. Cell cycle, ploidy, chromosomal aberrations 6. Apoptosis, cell immortalization Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090 
průměr: 5, hodnoceno: 1x
Wednesday27.03.202414:00 - 15:30 7. Cancer cell metabolism 8. Tumor radiobiology Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090 
průměr: 5, hodnoceno: 1x
Wednesday03.04.202414:00 - 15:30 9. Angiogenesis, metastatic process, circulating tumors cells, cell-free DNA and miRNAs 10. Immune response, tumor microenvironment, microbiome Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090 
průměr: 5, hodnoceno: 1x
Wednesday10.04.202414:00 - 15:30 11. Methods in molecular biology, predictive testing, tumor molecular classification 12. Molecular-based therapy, gene therapy Seminar room KBLDS4, Institute of Medical Biochemistry and Laboratory Diagnostics 1st Faculty of Medicine, Charles University, Kateřinská 32, ground floor, room number: 1.090 
 
Charles University | Information system of Charles University | http://www.cuni.cz/UKEN-329.html