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The course introduces basic approaches and models to describe molecular interactions. Emphasis is placed on
the practical implementation of the models on the computer and their application to experimental data.
Last update: Búryová Marcela (07.05.2024)
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credit in the form of written tests and processing of spectroscopic data, oral examination Last update: Búryová Marcela (07.05.2024)
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K.A. Connors, Binding Constants: The Measurement of Molecular Complex Stability, Wiley, 1987. P.W. Atkins, J. De Paula and J. Keeler, Atkins’ Physical Chemistry, Oxford University Press, 2018. E.V. Anslyn and D. A. Dougherty, Modern Physical Organic Chemistry, University Science Books, 2006. L. Lue, Chemical Thermodynamics, Ventus Publishing (Bookboon), 2014. L. Bartovská, Chemická kinetika, VŠChT Praha, 2008. C. A. Hunter and H. L. Anderson, What Is Cooperativity?, Ang. Chem. Int. Ed. 48, no. 41 (2009): 7488–99 Last update: Búryová Marcela (07.05.2024)
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I. Chemical reactions in equilibrium
Thermodynamics of chemical reactions spectroscopic methods, types of experiments supramolecular complexes, host-guest models cooperativity binding enthalpy and entropy, effect of temperature on chemical equilibrium II. chemical kinetics reaction rate, order of reaction conformational dynamics kinetics of enzymes, Michealis-Menten model effect of temperature on reaction rate, Eyring equation Last update: Búryová Marcela (07.05.2024)
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