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Course, academic year 2018/2019
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Structure, Dynamics and Functions of Biomembranes - NBCM014
Title in English: Struktura, dynamika a funkce biologických membrán
Guaranteed by: Institute of Physics of Charles University (32-FUUK)
Faculty: Faculty of Mathematics and Physics
Actual: from 2011
Semester: winter
E-Credits: 3
Hours per week, examination: winter s.:2/0 Ex [hours/week]
Capacity: unlimited
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Guarantor: prof. RNDr. Jaromír Plášek, CSc.
Classification: Physics > Biophysics and Chemical Physics
Annotation -
Last update: T_FUUK (18.05.2001)
Chemical composition and structure of biological membranes. Membrane lipids. Membrane proteins. Lipid-protein interactions. The interaction of small molecules with biomembranes. Electric properties of cell membranes, membrane potential. Pores, channels and transporters. Membrane fusion. Membrane spectroscopy. Biogenesis of biomembranes.
Syllabus -
Last update: T_FUUK (24.05.2004)

Fundamental concepts, chemical composition of biological membranes.

Membrane lipids. Thermodynamic principles. Water structure and hydrophobic

effect. Thermodynamic aspects of lipid aggregation/lipid polymorphism.

Phase transitions in lipid aggregates. Model lipid membranes, planar

membranes, liposomes. Membrane proteins, purification of membrane proteins,

experimental methods used to study protein structure, structure of membrane

proteins, the synthesis of membrane proteins and endoplasmic

reticulum. Lipid-protein interactions, membrane "fluidity". The

interaction of small molecules with biomembranes. Electric properties of

cell membranes, membrane potential. Pores, channels and transporters.

Membrane fusion. Membrane spectroscopy, fluorescence, NMR, EPR -

principles, instrumentation, applications.

 
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